| Budget Amount *help |
¥28,860,000 (Direct Cost: ¥22,200,000、Indirect Cost: ¥6,660,000)
Fiscal Year 2013: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2010: ¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
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| Outline of Final Research Achievements |
Phytophthora is a genus that infects and damages important crops such as potatoes and tomatoes. This phytopathogen sexually reproduces using mating hormones (alpha 1 and alpha 2), which are secreted by A1 and A2 mating types, respectively. The identification of the mating hormones had been a long-pending problem. In this project, we determined the chemical structures of these mating hormones, clarified the structure-activity relationship, biosynthetic process, and hormone universality. Furthermore, to identify the hormone receptors, fluorescent probes of alpha 1 were synthesized and found to selectively stain the A2 mating type, which could furnish alpha 1 receptor.
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