| Budget Amount *help |
¥45,370,000 (Direct Cost: ¥34,900,000、Indirect Cost: ¥10,470,000)
Fiscal Year 2014: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Fiscal Year 2013: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Fiscal Year 2012: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Fiscal Year 2011: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Fiscal Year 2010: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
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| Outline of Final Research Achievements |
Plant immune signaling mediated by chitin receptor was the subject of this project. Molecular mechanism of ligand-induced receptor dimerization and activation was clarified by biochemical and NMR studies. CERK1 autophosphorylation sites required for chitin responses were also identified. A cytoplasmic receptor-like kinase (RLK), PBL27, was shown to regulate chitin-induced gene expression and callose accumulation. It was also suggested that the signaling receptor kinases choose downstream RLKs based on their substrate specificity. Structural basis for the switching of defense and symbiotic responses by the kinase domains of LysM receptors was clarified. Dual function of a LysM receptor, OsCERK1, in defense and mycorhizal symbiosis was revealed, indicating close evolutional relationships of LysM receptors serving for these apparently opposite responses.
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