|Budget Amount *help
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2012: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
In order to examine the novel mechanism of neuropathic pain, especially interaction between spinal glial cells and neurons, we have used the rat model of neuropathic pain and explored the expression and the role of several molecules in nociceptive pathway. As a result, we have found several new findings and hypotheses about ATP receptors and lipid mediators in dorsal root ganglion neurons, spinal dorsal horn neurons and spinal glial cells. These results were published in international high-level journals.