Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2012: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2011: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2010: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
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Research Abstract |
We studied the molecular mechanisms of synaptic plasticity in this project. Inparticular, we focused on the GRIP protein on AMPA receptor trafficking, which plays a key role insynaptic plasticity expression. It turned out that GRIP is located in exocyst and play an importantfunction in AMPA receptor cell surface expression. In addition, we have established a system toaccurately introduce exogenous gene into hippocampus to study synaptic plasticity in vivo.
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