Creation of the Basic Technologies for "In Factory Tissue Engineering"
| Project/Area Number |
22300152
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | University of Toyama |
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Principal Investigator |
NAKAMURA Makoto 富山大学, 大学院・理工学研究部(工学), 教授 (90301803)
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| Co-Investigator(Kenkyū-buntansha) |
HORIE Mikio 東京工業大学, 精密工学研究所, 教授 (00126327)
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| Co-Investigator(Renkei-kenkyūsha) |
NIKAIDO Toshio 富山大学, 大学院・医学薬学研究部(医学), 教授 (50180568)
TAKEZAWA Toshiaki 独立行政法人農業生物資源研究所, 遺伝子組換え家畜研究センター, 主任研究員 (50301297)
SHIMADA Yutaka 富山大学, 京都大学, 大学院・医学薬学研究部(医学), ナノバイオ医薬創成科学, 准教授, 客員准教授 (30216072)
SUGIMOTO Naotoshi 金沢大学, 医学系, 准教授 (80272954)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2011: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
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| Keywords | バイオファブリケーション / 機械の手 / 工場生産 / バイオリアクター / 組織パーツ / 毛細血管 / 転写技術 / 印刷技術 / 人工臓器工学・再生医工学 / 細胞操作 / In factory tissue engineering / Biofabrication / Bioprinting / 再生医工学 / ロボティクス / 細胞組織 / 3次元造形 |
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| Research Abstract |
Many sequential processes are needed for manufacturing highly composite biological tissues which have micro-scaled and complicated structures. In this study, the concept of “In factory tissue engineering” was proposed, in which the tissues are produced through many processes where special manufacturing machines fabricate, assembly and process the biological products with cells, biomaterials and several tissue parts. Based on this concept, three major technologies were focused and developed; 1) manufacturing of tissue parts and tissue engineering materials, 2) assembly methods of tissue parts, 3) culture and control method for tissue formation.
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Report
(4 results)
Research Products
(125 results)
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[Journal Article] Polymer Brush with Pendent Glucosylurea Groups Constructed on a Glass Substrate by RAFT Polymerization,2012
Author(s)
Kitano H, Liu Y, Tokuwa K, Li L, Iwanaga S, Nakamura M, Kanayama N, Ohno K, Saruwatari Y,
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Journal Title
European Polymer Journal
Volume: 48
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Peer Reviewed
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[Presentation] 3D Fabrication technology using Bio- and Nano-materials.2012
Author(s)
Nakamura M, Shimatani T, FukaiN, Matsuba H, Ito H, Kawagishi T, OkinoS, Kuyo H, Sekiguchi N, Kanamaru R
Organizer
BioValley Life Sciences Week, Basel
Place of Presentation
Basel
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[Presentation] Application of printing technologies in producing complex tissues and organs.2012
Author(s)
Nakamura M, Arai K, Toda H, Yamamoto S, Kitano H, Nikaido T, Kobayashi Y, Watanabe T.
Organizer
Invited speaker： The Third Workshop of Synthetic Immunology: 2012, May18 - 19th, at Shiran Kaikan, Kyoto University, Kyoto, Japan
Place of Presentation
Kyoto
Related Report
Invited
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[Presentation] Computer-assisted designing and biofabrication of 3-D hydrogel structures towards thick 3-D tissue engineering,2011
Author(s)
Nakamura M, Arai K, Toda H, Iwanaga S, Ito K, Capi G, Nikaido T,
Organizer
Invited lecture, 2011 MRS fall symposium,
Place of Presentation
Boston, USA
Related Report
Invited
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[Presentation] 3D Fabrication technology using Bio- and Drug-Development from Bench to Enduser; and Nano-materials
Author(s)
Makoto Nakamura, Takao Shimatani, Nobue Fukai, Hiroko Matsuba, Hiroko Ito, Takahiro Kawagishi, Satoshi Okino, Hideo Kuyo, Noriaki Sekiguchi, Ryoji Kanamaru,
Organizer
シンポジウム講演：International Symposium on Biomedicine BioValley Life Sciences Week, Basel, September 22-29, 2012
Place of Presentation
Basel, Swizerland
Related Report
Invited
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