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The microRNAsfor the diagnosis and treatment of uppergastro-intestinal malignancy - application of appatite-nanocarrier -

Research Project

Project/Area Number 22300169
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionKeio University

Principal Investigator

SUZUKI Hidekazu  慶應義塾大学, 医学部, 准教授 (70255454)

Co-Investigator(Kenkyū-buntansha) SAITO Yoshimasa  慶應義塾大学, 薬学部, 准教授 (90360114)
AKAIKE Toshihiro  東京工業大学, 生命理工学部, 教授 (30101207)
KANAI Yae  国立がん研究センター, 研究所, 副所長 (00260315)
ONISHI Yasuyuki  実験動物中央研究所, 研究員 (70201382)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
Fiscal Year 2012: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
KeywordsマイクロRNA / アパタイトナノキャリア / がん遺伝子 / 胃がん / 担がん動物 / 細胞内導入 / 胃癌 / シスプラチン / 5-FU / NOGマウス / 癌幹細胞 / 食道腺癌 / 癌遺伝子 / 担癌動物
Research Abstract

The microRNAs (miRNAs) regulate both tumor development and progression by acting on tumor promoter or suppressor genes. Here, a delivery mechanism to introduce miRNA into the cytoplasm by using apatite nanoparticle is applied. 1) An miRNA microarray analy

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (128 results)

All 2013 2012 2011 2010 Other

All Journal Article (63 results) (of which Peer Reviewed: 63 results) Presentation (58 results) Book (5 results) Remarks (2 results)

  • [Journal Article] Helicobacter pyloriinfection in functional dyspepsia.2013

    • Author(s)
      Suzuki, H., Moayyedi, P.
    • Journal Title

      Nat. Rev. Gastroenterol. Hepatol.

      Volume: 10(3) Issue: 3 Pages: 168-74

    • DOI

      10.1038/nrgastro.2013.9

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The role of microRNAin gastric malignancy.2013

    • Author(s)
      Nishizawa, T., Suzuki, H
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 14(5) Issue: 5 Pages: 9487-9496

    • DOI

      10.3390/ijms14059487

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The tumor suppressor microRNA -29c is downregulated and restored by celecoxib in human gastric cancer cells2013

    • Author(s)
      Saito Y, Suzuki H, Imaeda H, Matsuzaki J, et al.
    • Journal Title

      International Journal of Cancer

      Volume: 132 Issue: 8 Pages: 1751-1760

    • DOI

      10.1002/ijc.27862

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors.2013

    • Author(s)
      Manabu Nakashita
    • Journal Title

      Dig. Dis. Sci.

      Volume: 58 Pages: 354-62

    • DOI

      10.1007/s10620-012-2350-x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Minimally invasive surgery for esophageal epiphrenic diverticulum – the results of our experience and 133 patients in 25 published series.2013

    • Author(s)
      Yuki Hirano
    • Journal Title

      Surgery Today

      Volume: 43 Issue: 1 Pages: 1-7

    • DOI

      10.1007/s00595-012-0386-3

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of ursodeoxycholic acid and endoscopic sphincterotomy in long-term stenting for common bile duct stones.2013

    • Author(s)
      Toshihiro Nishizawa
    • Journal Title

      J. Gastroenterol. Hepatol.

      Volume: 28 Issue: 1 Pages: 63-7

    • DOI

      10.1111/jgh.12012

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Improvement of reflux symptom related quality of life after <i>Helicobacter pylori</i> eradication therapy2013

    • Author(s)
      Kenro Hirata
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 52 Issue: 2 Pages: 172-178

    • DOI

      10.3164/jcbn.12-107

    • NAID

      130004466704

    • ISSN
      0912-0009, 1880-5086
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Musashi-1 post-transcriptionally enhances phosphotyrosine-binding domain- containing m-Numb protein expression in regenerating gastric mucosa.2013

    • Author(s)
      Tetsufumi Takahashi
    • Journal Title

      PLoS One

      Volume: 8 Issue: 1 Pages: 1-13

    • DOI

      10.1371/journal.pone.0053540

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impaired heme oxygenase-1 induction in the gastric antrum induces disruption of the interstitial cells of Cajal network in a rat model of streptozotocin-induced diabetes.2013

    • Author(s)
      Sachiko Mogami
    • Journal Title

      Neurogastroenterol. Motil.

      Volume: in press Issue: 7 Pages: 609-609

    • DOI

      10.1111/nmo.12122

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Validation of the GerdQ questionnaire for the management of gastro-oesophageal reflux disease in Japan2013

    • Author(s)
      Suzuki H, Matsuzaki J, Okada S, et al.
    • Journal Title

      United European Gastroenterology Journal

      Volume: (印刷中) Issue: 3 Pages: 175-183

    • DOI

      10.1177/2050640613485238

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FecA1, a bacterial iron transporter, determines the survival of Helicobacter pylori in the stomach2012

    • Author(s)
      Tsugawa H, Suzuki H, Matsuzaki J, et al
    • Journal Title

      Free Radic Biol Med

      Volume: 52 Issue: 6 Pages: 1003-1010

    • DOI

      10.1016/j.freeradbiomed.2011.12.011

    • Related Report
      2012 Annual Research Report 2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low-density lipoprotein receptorrelated protein-1 (LRP-1) mediates autophagy and apoptosis caused by Helicobacter pyloriVacA2012

    • Author(s)
      Yahiro, K., Suzuki, H., et al.
    • Journal Title

      J. Biol. Chem

      Volume: 287(37) Issue: 37 Pages: 31104-15

    • DOI

      10.1074/jbc.m112.387498

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of a novel microRNA promoter microarray for ChIP-on chip assay to identify epigenetically regulated microRNAs2012

    • Author(s)
      Saito Y, Suzuki H, Taya T, Nishizawa M, Tsugawa H, Matsuzaki J, et al.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 426 Issue: 1 Pages: 33-37

    • DOI

      10.1016/j.bbrc.2012.08.012

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Overexpression of miR-142-5p and miR-155 in Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma Resistant to Helicobacter pylori Eradication2012

    • Author(s)
      Saito y, Suzuki H, Tsugawa H, Imaeda H, Matsuzaki J, et al.
    • Journal Title

      PLoS One

      Volume: 7 Issue: 11 Pages: e47396-e47396

    • DOI

      10.1371/journal.pone.0047396

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reactive Oxygen Species-Induced Autophagic Degradation of Helicobacter pylori CagA Is Specifically Suppressed in Cancer Stem-like Cells2012

    • Author(s)
      Tsugawa H, Suzuki H, Saya H, Hatakeyama M, Hirayama T, Hirata K, Nagano 0, Matsuzaki J, et al.
    • Journal Title

      Cell Host & Microbe

      Volume: 12 Issue: 6 Pages: 764-777

    • DOI

      10.1016/j.chom.2012.10.014

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] CDX1 directs gastric intestinal metaplasia via induction of stemness-associated reprogramming factors SALL4 and KLF52012

    • Author(s)
      Fujii, Y.
    • Journal Title

      Proc. Natl. Acad. Sci.USA

      Volume: 109 Issue: 50 Pages: 20584-20589

    • DOI

      10.1073/pnas.1208651109

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced gastric ghrelin production and secretion in rats with gastric outlet obstruction.2012

    • Author(s)
      Iwasaki E
    • Journal Title

      Dig Dis Sci

      Volume: 57 Issue: 4 Pages: 858-864

    • DOI

      10.1007/s10620-011-1953-y

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduced ghrelin production induced anorexia after rat gastric ischemia and reperfusion2012

    • Author(s)
      Mogami S, Suzuki H, Fukuhara S, Matsuzaki J, et al
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 302 Issue: 3 Pages: G359-G364

    • DOI

      10.1152/ajpgi.00297.2011

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Proton pump inhibitor-amoxicillin-clarithromycin versus proton pump inhibitor-amoxicillin-metronidazole as first-line <i>Helicobacter pylori</i> eradication therapy2012

    • Author(s)
      Toshihiro Nishizawa
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 51 Issue: 2 Pages: 114-116

    • DOI

      10.3164/jcbn.D-11-00029R1

    • NAID

      130004879303

    • ISSN
      0912-0009, 1880-5086
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of sitafloxacin-based rescue therapy for Helicobacter pylori after failures of first- and second-line therapies.2012

    • Author(s)
      Juntaro Matsuzaki
    • Journal Title

      Antimicrob. Agent Chemother.

      Volume: 56 Issue: 3 Pages: 1643-45

    • DOI

      10.1128/aac.05941-11

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Capsule endoscopy assists in the complete deworming of parasites.2012

    • Author(s)
      Shinsuke Kobayashi
    • Journal Title

      J. Gastroenterol. Hepatol.

      Volume: 27 Issue: 7 Pages: 1253-1253

    • DOI

      10.1111/j.1440-1746.2012.07154.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Classification of functional dyspepsia based on concomitant bowel symptoms2012

    • Author(s)
      Matsuzaki J, Suzuki H, Asakura K, et al
    • Journal Title

      Neurogastroenterol Motil

      Volume: 24 Issue: 4 Pages: 1643-1645

    • DOI

      10.1111/j.1365-2982.2011.01859.x

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of β-(1,3-1,6)-D-glucan on irritable bowel syndrome-related colonic hypersensitivity2012

    • Author(s)
      Asano, T., Suzuki, H., et al
    • Journal Title

      Biochem.Biophys.Res.Com.

      Volume: 420(2) Issue: 2 Pages: 444-449

    • DOI

      10.1016/j.bbrc.2012.03.015

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dual therapy for third-line H. pylori eradication and urea breath test prediction.2012

    • Author(s)
      Toshihiro Nishizawa
    • Journal Title

      World J. Gastroenterol.

      Volume: 18 Issue: 21 Pages: 2735-2738

    • DOI

      10.3748/wjg.v18.i21.2735

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of Solifenacin on Irritable Bowel Syndrome With Diarrhea : Open-label Prospective Pilot Trial.2012

    • Author(s)
      Fukushima Y, Suzuki H, Matsuzaki J, et al.
    • Journal Title

      Journal of Neurogastroenterology and Motility

      Volume: 18 Issue: 3 Pages: 317-323

    • DOI

      10.5056/jnm.2012.18.3.317

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High frequency of overlap between functional dyspepsia and overactive bladder2012

    • Author(s)
      Matsuzaki J, Suzuki H, Fukushima Y, et al.
    • Journal Title

      Neurogastroenterology and Motility

      Volume: 24 Issue: 9 Pages: 821-827

    • DOI

      10.1111/j.1365-2982.2012.01939.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transmural pressure loading enhances gastric mucosal proliferation.2012

    • Author(s)
      Hiromasa Nakamizo
    • Journal Title

      Dig. Dis. Sci.

      Volume: 57 Pages: 2545-2554

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Questionnaire-Based Survey on Screening for gastric and colorectal cancer by physicians in East Asian countries in 2010.2012

    • Author(s)
      Yuji Naito
    • Journal Title

      Digestion

      Volume: 86 Issue: 2 Pages: 94-106

    • DOI

      10.1159/000339342

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Questionnaire-based survey conducted in 2011 concerning endoscopic management of Barrett’s esophagus in East Asian countries.2012

    • Author(s)
      Norihisa Ishimura
    • Journal Title

      Digestion

      Volume: 86 Issue: 2 Pages: 136-146

    • DOI

      10.1159/000339778

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Are solifenacin and ramosetron really ideal to treat irritable bowel syndrome?: Author’s Reply.2012

    • Author(s)
      Hidekazu Suzuki
    • Journal Title

      J. Neurogastroenterol. Motil.

      Volume: 18 Issue: 4 Pages: 459-459

    • DOI

      10.5056/jnm.2012.18.4.459

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of a unique nsaid, fluoro-loxoprofen with gastroprotective activity.2012

    • Author(s)
      Suemasu S., et al.
    • Journal Title

      Biochem Pharmacol.

      Volume: 84 Issue: 11 Pages: 1470-1481

    • DOI

      10.1016/j.bcp.2012.09.016

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular approaches and modern clinical strategies for the management of Helicobacter pylori infection in Japan.2012

    • Author(s)
      Hidekazu Suzuki
    • Journal Title

      Keio J. Med.

      Volume: 61 Pages: 109-119

    • NAID

      10031140763

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced gastric ghrelin induced c-kit protein expression in rats with gastric outlet obstruction.2012

    • Author(s)
      Eisuke Iwasaki
    • Journal Title

      Dig. Dis. Sci.

      Volume: 57 Issue: 12 Pages: 3308-3309

    • DOI

      10.1007/s10620-012-2451-6

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biliary Findings Assist in Predicting Enlargement of Intraductal Papillary Mucinous Neoplasms of the Pancreas2012

    • Author(s)
      Matsuzaki J, Suzuki H, Okuda S, et al.
    • Journal Title

      Clininal Gastroenterology and Hepatology

      Volume: (印刷中) Issue: 5 Pages: 548-554

    • DOI

      10.1016/j.cgh.2012.11.027

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Capsule endoscopy assists in the complete deworming of parasites2012

    • Author(s)
      Kobayashi, S., Suzuki, H., et al
    • Journal Title

      J.Gastroenterol.Hepatol.

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Minimally invasive surgery for esophageal epiphrenic diverticulum-the results of our experience and 133 patients in 25 published series2012

    • Author(s)
      Hirano, Y., Suzuki, H., et al
    • Journal Title

      Surgery Today

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular approaches and modem clinical strategies for the management of Helicobacter pylori infection in Japan2012

    • Author(s)
      Suzuki, H., et al
    • Journal Title

      Keio J.Med.

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Roles of oxidative stress in stomach disorders2011

    • Author(s)
      Suzuki, H., et al.
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 50 Issue: 1 Pages: 35-39

    • DOI

      10.3164/jcbn.11-115SR

    • NAID

      130004466668

    • ISSN
      0912-0009, 1880-5086
    • Related Report
      2012 Annual Research Report 2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two amino acids mutation of Ferric uptake regulator (Fur) determines Helicobacter pylori resistance to metronidazole.2011

    • Author(s)
      Tsugawa, H., Suzuki, H., Saito, Y., et al.
    • Journal Title

      Antioxid. Redox Signal

      Volume: 14(1) Issue: 1 Pages: 15-23

    • DOI

      10.1089/ars.2010.3146

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dysfunctional gastric emptying with downregulation of muscle-specific microRNAs in Helicobacter pylori -infected mice.2011

    • Author(s)
      Saito, Y., Suzuki, H., et al.
    • Journal Title

      Gastroenterology

      Volume: 140(1) Issue: 1 Pages: 189-198

    • DOI

      10.1053/j.gastro.2010.08.044

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Etiological difference between ultrashort-segment Barrett's esophagus and short-segment Barrett's esophagus in Japan2011

    • Author(s)
      Matsuzaki, J., Suzuki, H., Saito, Y., et al.
    • Journal Title

      J. Gastroenterol.

      Volume: 46(3) Issue: 3 Pages: 332-8

    • DOI

      10.1007/s00535-010-0353-y

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Extragastric manifestations of Helicobacter pylori infection.2011

    • Author(s)
      Suzuki, H., et al.
    • Journal Title

      Helicobacter

      Volume: 16(Suppl.1) Issue: s1 Pages: 65-69

    • DOI

      10.1111/j.1523-5378.2011.00883.x

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of lansoprazole versus roxatidine on prevention of bleeding and ulcer healing after endoscopic submucosal dissection for superficial gastric neoplasia2011

    • Author(s)
      Imaeda, H., Suzuki, H., Saito, Y., et al.
    • Journal Title

      J. Gastroenterol.

      Volume: 46(11) Issue: 11 Pages: 1267-72

    • DOI

      10.1007/s00535-011-0447-1

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MicroRNAs in hepatobiliary and pancreatic cancers.2011

    • Author(s)
      Saito, Y., Suzuki, H., et al.
    • Journal Title

      Front. Gene.

      Volume: 2 Pages: 66-66

    • DOI

      10.3389/fgene.2011.00066

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Can Helicobacter pylori-associated dyspepsia be categorized as functional dyspepsia?2011

    • Author(s)
      Suzuki, H., et al
    • Journal Title

      J.Gastroenterol.Hepatol.

      Volume: 26(s3) Issue: s3 Pages: 42-45

    • DOI

      10.1111/j.1440-1746.2011.06629.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] What is the difference between Helicobacter pylori-associated dyspepsia and functional dyspepsia?2011

    • Author(s)
      Suzuki H, Matsuzaki J, Hibi T
    • Journal Title

      J Neurogastroentewl Motil

      Volume: 17 Issue: 2 Pages: 124-130

    • DOI

      10.5056/jnm.2011.17.2.124

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhancement of annoxicillin resistance after unsuccessful Helicobacter pylorieradication2011

    • Author(s)
      Nishizawa T, Suzuki H, Tsugawa H, Muraoka H, Matsuzaki J, et al
    • Journal Title

      Antimicrob Agents Chemother

      Volume: 52 Issue: 6 Pages: 3012-3014

    • DOI

      10.1128/aac.00188-11

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Proton pump inhibitors for the treatment of functional dyspepsia2011

    • Author(s)
      Suzuki, H., et al
    • Journal Title

      Ther.Adv.Gastroenterol.

      Volume: 4(4) Issue: 4 Pages: 219-226

    • DOI

      10.1177/1756283x11398735

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Trainee participation during colonoscopy adversely affects the rates of polyp and adenoma detection2011

    • Author(s)
      Nishizawa, T., Suzuki, H., et al
    • Journal Title

      Digestion

      Volume: 84(3) Issue: 3 Pages: 245-246

    • DOI

      10.1159/000330736

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bovine antibody-based oral immunotherapy for reduction of intragastric Helicobacter pylori colonization : a randomized clinical trial2011

    • Author(s)
      den Hoed, C.M., Suzuki, H., et al
    • Journal Title

      Can.J.Gastroenterol.

      Volume: 25(4) Pages: 207-213

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Helicobacter pylori resistance to rifabutin in the last 7 years2011

    • Author(s)
      Nishizawa T, Suzuki H, Matsuzaki J, et al
    • Journal Title

      Antimicrob Agents Chemother

      Volume: 55 Issue: 11 Pages: 5374-5375

    • DOI

      10.1128/aac.05437-11

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metronidazole-based quadruple versus standard triple therapy : which is better as first-line therapy for Helicobacter pylori eradication?2011

    • Author(s)
      Suzuki H, Matsuzaki, Hibi T
    • Journal Title

      Expert Rev Clin Pharmacol

      Volume: 4 Issue: 5 Pages: 579-582

    • DOI

      10.1586/ecp.11.34

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Overlap syndrome of functional dyspepsia and irritable bowel syndrome-are both diseases mutually exclusive?-2011

    • Author(s)
      Suzuki, H., Hibi, T.
    • Journal Title

      J.Neurogastroenterol.Motil.

      Volume: 17(4) Issue: 4 Pages: 360-365

    • DOI

      10.5056/jnm.2011.17.4.360

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dysfunctional gastric emptying with down-regulation of muscle-specific MicroRNAs in Helicobacter pylori-infected mice2011

    • Author(s)
      Saito, Y., Suzuki, H, et al.
    • Journal Title

      Gastroenterology

      Volume: 140(1) Pages: 189-198

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two amino acids mutation of ferric uptake regulator determines Helicobacter pylori Resistance to Metronidazole.2011

    • Author(s)
      Tsugawa, H., Suzuki, H., et al.
    • Journal Title

      Antioxidants and Redox signaling

      Volume: 14(1) Pages: 15-23

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced bacterial efflux system is the first step to the development of metronidazole resistance in Helicobacter pylori.2011

    • Author(s)
      Tsugawa, H., Suzuki, H., et al.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 404(2) Pages: 656-660

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Etiological difference between ultrashort- and short-segment Barrett's esophagus2011

    • Author(s)
      Matsuzaki, J., Suzuki, H., et al.
    • Journal Title

      Journal of Gastroenterology

      Volume: 46(3) Pages: 332-338

    • NAID

      10029027814

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhancement of amoxicillin resistance after unsuccessful Helicobacter pylori eradication2011

    • Author(s)
      Nishizawa, T., Suzuki, H., et al.
    • Journal Title

      Antimicrobial Agents and Chemotherapy

      Volume: (In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gallstones increase the prevalence of Barrett's esophagus.2010

    • Author(s)
      Matsuzaki, J., Suzuki, H., Saito, Y., et al.
    • Journal Title

      J. Gastroenterol.

      Volume: 45(2) Issue: 2 Pages: 171-8

    • DOI

      10.1007/s00535-009-0153-4

    • NAID

      10027214436

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Contribution of efflux pumps to clarithromycin resistance in Helicobacter pylori2010

    • Author(s)
      Hirata, K., Suzuki, H., Saito, Y., et al.
    • Journal Title

      J. Gastroenterol. Hepatol.

      Volume: 25(s1) Issue: s1

    • DOI

      10.1111/j.1440-1746.2009.06220.x

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ghrelin and oxidative stress in gastrointestinal tract2010

    • Author(s)
      Suzuki, H., et al
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 48 Issue: 2 Pages: 122-125

    • DOI

      10.3164/jcbn.10-16GFR

    • NAID

      130004466636

    • ISSN
      0912-0009, 1880-5086
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Serum lipid levels are positively associated with non-erosive reflux disease, but not with functional heartburn.2010

    • Author(s)
      Matsuzaki, J., Suzuki, H., et al.
    • Journal Title

      Neurogastroenterology and Motility

      Volume: 22(9) Pages: 965-970

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acid suppression by proton pump inhibitors enhances aquaporin-4 and kcnq1 expression in gastric fundic parietal cells in mouse.2010

    • Author(s)
      Matsuzaki, J., Suzuki, H., et al.
    • Journal Title

      Digestive Diseases and Sciences

      Volume: 55(12) Pages: 3339-3348

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Resistance to oxidative stress is a principal pathway for the survival and disease development of Helicobacter pylori. "Helicobacter pylori and Tissue Injury"2012

    • Author(s)
      Suzuki, H., et al.
    • Organizer
      7th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2012-09-11
    • Related Report
      2012 Final Research Report
  • [Presentation] Helicobacter pyloriand gastric cancer. Symposium 7 "Helicobacter pylori-Pathogenesis & Clinical Manifestation-"2012

    • Author(s)
      Suzuki, H.
    • Organizer
      The 14th Meeting of International Conference on Ulcer Research (ICUR)
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2012-07-13
    • Related Report
      2012 Final Research Report
  • [Presentation] Specific amino acid mutation of p53 enhanced the stability of intracellular cagAby inhibiting autophagy induction.2012

    • Author(s)
      Tsugawa, H., Suzuki, H., et al.
    • Organizer
      AGA Research Forum, DDW2012
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2012-05-12
    • Related Report
      2012 Final Research Report
  • [Presentation] Dysfunctional gastric emptying with downregulation of muscle-specific microRNAs in Helicobacter pylori -infected mice.2012

    • Author(s)
      Saito, Y., Suzuki, H., et al.
    • Organizer
      The 2nd Asian Pacific Topic Conference, Asian Pacific Helicobacter pylori Meeting 2012
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Related Report
      2012 Final Research Report
  • [Presentation] GERDQ is superior tool for the evaluation of GERD symptoms and unmet medical needs to the Carlsson-Dent questionnaire – a large scale survey –2012

    • Author(s)
      Hidekazu Suzuki
    • Organizer
      Digestive Disease Week 2012
    • Place of Presentation
      San Diego, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] GERDQ is an easy and useful tool for assessing the severity of gastroesophageal reflux disease and identifying patients with “unmet medical needs”.2012

    • Author(s)
      Sawako Okada
    • Organizer
      Digestive Disease Week 2012
    • Place of Presentation
      San Diego, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Dynamics of aquaporin-4 in gastric parietal cells in the hyperplastic gastric fundic mucosa of histamine type 2 receptor knockout mice.2012

    • Author(s)
      Seiichiro Fukuhara
    • Organizer
      Digestive Disease Week 2012
    • Place of Presentation
      San Diego, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Specific amino acid mutation of p53 enhanced the stability of intracellular cagA by inhibiting autophagy induction.2012

    • Author(s)
      Hitoshi Tsugawa
    • Organizer
      Digestive Disease Week 2012
    • Place of Presentation
      San Diego, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] MicroRNA-21 expression causes nuclear loss of the tumor suppressor PDCD4 in precancerous gastric adenomas.2012

    • Author(s)
      Kenro Hirata
    • Organizer
      Digestive Disease Week 2012
    • Place of Presentation
      San Diego, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] The extension of mucosal lesions, Helicobacter pylori infection status and API2-MALT1 positivity are associated with the therapeutic response for gastric MALT lymphoma.2012

    • Author(s)
      Sawako Okada
    • Organizer
      Digestive Disease Week 2012
    • Place of Presentation
      San Diego, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Evaluation of CD44 variant expression as a recurrence marker of gastric cancer after endoscopic submucosal dissection.2012

    • Author(s)
      Kenro Hirata
    • Organizer
      The 10th annual meeting of the International Society for Stem Cell Research (ISSCR)
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Helicobacter pylori and gastric cancer. Symposium 7 “Helicobacter pylori -Pathogenesis & Clinical Manifestation-“2012

    • Author(s)
      Hidekazu Suzuki
    • Organizer
      The 14th Meeting of International Conference on Ulcer Research (ICUR)
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Dynamics of aquaporin-4 in gastric parietal cells in the gastric fundic mucosa of histamine type 2 receptor knockout mice with Helicobacter pylori infection.2012

    • Author(s)
      Seiichiro Fukuhara
    • Organizer
      The 14th Meeting of International Conference on Ulcer Research (ICUR)
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Impaired heme oxygenase-1 upregulation induced decreased interstitial cells of Cajal in streptozotocin-induced diabetes model.2012

    • Author(s)
      Sachiko Mogami
    • Organizer
      The 14th Meeting of International Conference on Ulcer Research (ICUR)
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] A comprehensive and active educational program for medical students to attract their interests toward research scientists at Keio University School of Medicine in Japan.2012

    • Author(s)
      Michito Hirakata
    • Organizer
      AMEE (Association for Medical Education in Europe) 2012
    • Place of Presentation
      Lyon, France
    • Related Report
      2012 Annual Research Report
  • [Presentation] High frequency of overlap between functional dyspepsia, irritable bowel syndrome and overactive bladder.2012

    • Author(s)
      Hidekazu Suzuki
    • Organizer
      2012 Joint International Neurogastroenterology and Motility Meeting (NGM2012)
    • Place of Presentation
      Bologna, Italy
    • Related Report
      2012 Annual Research Report
  • [Presentation] The GerdQ is a useful tool for evaluating the patients’ satisfaction and identifying the patients with “unmet medical needs”.2012

    • Author(s)
      Sawako Okada
    • Organizer
      2012 Joint International Neurogastroenterology and Motility Meeting (NGM2012)
    • Place of Presentation
      Bologna, Italy
    • Related Report
      2012 Annual Research Report
  • [Presentation] Improvement in the quality of life related to reflux symptoms after Helicobacter pylori eradication therapy.2012

    • Author(s)
      Kenro Hirata
    • Organizer
      2012 Joint International Neurogastroenterology and Motility Meeting (NGM2012)
    • Place of Presentation
      Bologna, Italy
    • Related Report
      2012 Annual Research Report
  • [Presentation] Resistance to oxidative stress is a principal pathway for the survival and disease development of Helicobacter pylori. “Helicobacter pylori and Tissue Injury”2012

    • Author(s)
      Hidekazu Suzuki
    • Organizer
      7th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection
    • Place of Presentation
      Honolulu, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Predictive Factors for the Increase in Size of Branch Duct-type Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Retrospective Cohort Study with a 6-year Follow-up.2012

    • Author(s)
      Hidekazu Suzuki
    • Organizer
      The American College of Gastroenterology Annual Scientific Meeting (ACG2012)
    • Place of Presentation
      Las Vegas, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Eradication of Helicobacter pylori with 10-day sitafloxacin-based triple therapy as a third- or fourth-line rescue therapy: preliminary results of open-label randomized trial.2012

    • Author(s)
      Hideki Mori
    • Organizer
      The American College of Gastroenterology Annual Scientific Meeting (ACG2012)
    • Place of Presentation
      Las Vegas, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Things to consider before submitting papers from Eastern authors to Western Journals – viewpoint of the Associate Editor of the “American Journal of Gastroenterology”.2012

    • Author(s)
      Hidekazu Suzuki
    • Organizer
      Seoul International Digestive Disease Symposium 2012 (SIDDS2012)
    • Place of Presentation
      Seoul, Korea
    • Related Report
      2012 Annual Research Report
  • [Presentation] High eradication rates of Helicobacter pylori with sitafloxacin-based 10 days-triple therapy as a third-line treatment.2012

    • Author(s)
      Hideki Mori
    • Organizer
      Seoul International Digestive Disease Symposium 2012 (SIDDS2012)
    • Place of Presentation
      Seoul, Korea
    • Related Report
      2012 Annual Research Report
  • [Presentation] The Role of Helicobacter pylori infection in the disease entity of functional dyspepsia.2012

    • Author(s)
      Hidekazu Suzuki
    • Organizer
      Seoul International Digestive Disease Symposium 2012 (SIDDS2012)
    • Place of Presentation
      Seoul, Korea
    • Related Report
      2012 Annual Research Report
  • [Presentation] Frequent overlap of overactive bladder with functional dyspepsia and/or irritable bowel syndrome2011

    • Author(s)
      Suzuki, H., et al
    • Organizer
      The American College of Gastroenterology Annual Scientific Meeting (ACG2011)
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2011-10-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] Proliferation of cdx2-expressing human esophageal cells is enhanced by bile acid with upregulation.2011

    • Author(s)
      Matsuzaki, J., Suzuki, H., Saito, Y., and Akaike, T., et al.
    • Organizer
      UEGW2011
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2011-10-25
    • Related Report
      2012 Final Research Report
  • [Presentation] GerdQ is superior for the evaluation of age-dependent symptom aggravation and for the reflection of patients' satisfaction with prescribed medications to the carlsson-dent questionnaire2011

    • Author(s)
      Suzuki, H., et al
    • Organizer
      19th United European Gastroenterology Week 2011
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2011-10-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Are functional dyspepsia and irritable bowel syndrome mutually exclusive?2011

    • Author(s)
      Suzuki, H.
    • Organizer
      The 12th Recent update of Neurogastroenterology & Motility Symposium
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2011-06-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] H.pyloriの病原・薬剤耐性獲得機序-慢性持続性感染による宿主応答から-2011

    • Author(s)
      鈴木秀和, 津川仁, 日比紀文
    • Organizer
      第97回日本消化器病学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2011-05-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] Activation of the tumor suppressor microRNA-29cby the selective cyclooxygenase-2 inhibitor, celecoxib in human gastric cancer.2011

    • Author(s)
      Suzuki, H., Saito, Y., Kanai, Y., et al
    • Organizer
      AGA Research Forum DDW2011
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2011-05-09
    • Related Report
      2012 Final Research Report
  • [Presentation] Activation of the tumor suppressor microRNA-29c by the selective cyclooxygenase-2 inhibitor, celecoxib in human gastric cancer2011

    • Author(s)
      Suzuki, H., et al
    • Organizer
      AGA Research Forum "Targeted therapy and GI cancers" Digestive Disease Week 2011
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2011-05-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] H. pylori-Derived Oncoprotein, CagA, is Degraded by Autophagy in Human Gastric Epithelial Cells.2011

    • Author(s)
      Tsugawa, H., Suzuki, H., et al
    • Organizer
      AGA Research Forum DDW2011
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2011-05-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Enhanced Expression of MicroRNA-142-5p and MicroRNA-155 and Suppressed Expression of Tp53inp1 Would Be Novel Molecular Biomarkers for Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma, Resistant to H. pylori Eradication.2011

    • Author(s)
      Suzuki, H., Saito, Y., et al.
    • Organizer
      AGA Research Forum DDW2011
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2011-05-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Enhanced expression of microRNA-142-5p and microRNA-155 and suppressed expression of TP53INP1 would be novel molecular biomarkers for gastric mucosa-associated lymphoid tissue (MALT) lymphoma, resistant to H.pylori eradication2011

    • Author(s)
      Suzuki, H., et al
    • Organizer
      AGA Topic Forum "Biomarkers in GI cancers" Digestive Disease Week 2011
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2011-05-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] The selective cyclooxygenase-2 inhibitor celecoxib activates the tumor suppressor microRNA-29c in human gastric cancer.2011

    • Author(s)
      Saito, Y., Suzuki, H, et al.
    • Organizer
      第7回日本消化管学会, 4^<th> IGICS
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2011-02-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Upregulation of oncogenic microRNA-21followed by the downregulation of the tumor suppressor microRNA-29cin the progression of human gastric cancer.2010

    • Author(s)
      Suzuki, H., Saito, Y., Kanai, Y., et al
    • Organizer
      UEGW2010
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-10-25
    • Related Report
      2012 Final Research Report
  • [Presentation] Upregulation of oncogenic microRNA-21 followed by the downregulation of the tumor suppressor microRNA-29c in the progression of human gastric cancer.2010

    • Author(s)
      Suzuki, H.
    • Organizer
      18th United European Gastroenterology Week (UEGW2010)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-10-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Gastric cancer development - from the aspects of sonic hedgehog and microRNAs-.2010

    • Author(s)
      Suzuki, H.
    • Organizer
      Gachon International Gastric Cancer Symposium 2010
    • Place of Presentation
      Incheon, Korea
    • Year and Date
      2010-10-09
    • Related Report
      2012 Final Research Report
  • [Presentation] Gastric cancer development-from the aspects of sonic hedgehog and microRNAs-.2010

    • Author(s)
      Suzuki, H.
    • Organizer
      Gachon International Gastric Cancer Symposium 2010
    • Place of Presentation
      Incheon, Korea
    • Year and Date
      2010-10-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Nitric oxide involvement in gastric disorders.2010

    • Author(s)
      Suzuki, H. (invited), Saito, Y., et al
    • Organizer
      Symposium SP-04 "Nitrosative stress in the gastrointestinal tract", The 6thInternational Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-06-15
    • Related Report
      2012 Final Research Report
  • [Presentation] Nitric oxide involvement in gastric disorders.2010

    • Author(s)
      Suzuki, H
    • Organizer
      The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2010-06-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] Downregulation of the tumor suppressor microRNA-29c plays a critical role in the progression of human gastric cancer.2010

    • Author(s)
      Saito, Y., Suzuki, H, et al.
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-05-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] microRNA-21 plays a critical role in Helicobacter pylori-associated gastric cancer by suppressing BTG2.2010

    • Author(s)
      Ikura, A., Suzuki, H, et al.
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-05-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] Gastric Cancer Screening in Japanese.2010

    • Author(s)
      Suzuki, H.
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-05-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] High prevalence of lower gastrointestinal (GI) symptoms in functionaldyspepsia : a factor and cluster analysis in the general population2010

    • Author(s)
      Suzuki, H., et al.
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-05-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] Sitafloxacin-based third-line eradication of H.pylori.2010

    • Author(s)
      Suzuki.H., et al.
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-05-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] Increased Expression of microRNA-21 is an early event in human gastric carcinogenesis.2010

    • Author(s)
      Hirata, K., Suzuki, H, et al.
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-05-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] Overexpression of miR-142-5p and miR-155 and suppression of tumor protein 53-induced nuclear protein 1 in gastric mucosa-associated lymphoid tissue lymphoma.2010

    • Author(s)
      Saito, Y., Suzuki, H., et al.
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-05-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Chronic infection with Helicobacter pylori induces downregulation of muscle-specific microRNAs and smooth muscle hypertrophy of the mouse stomach.2010

    • Author(s)
      Saito, Y., Suzuki, H., et al.
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-05-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Caudal-related homeobox 2 (Cdx2) suppresses stratification of esophageal squamous epithelial cells by down-regulating microRNA-221/2222010

    • Author(s)
      Matsuzaki, J., Suzuki, H, et al.
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-05-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] マイクロRNAを介した胃癌に対するエピジェネティック治療2010

    • Author(s)
      斎藤義正, 鈴木秀和, ら
    • Organizer
      第96回日本消化器病学会総会
    • Place of Presentation
      新潟市
    • Year and Date
      2010-04-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Gastric Cancer Screening in Japanese2010

    • Author(s)
      Suzuki, H.
    • Organizer
      ASGE Clinical Symposium DDW2010
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Overexpression of miR-142-5pand miR-155and suppression of tumor protein 53-induced nuclear protein 1 in gastric mucosa-associated lymphoid tissue lymphoma.2010

    • Author(s)
      Saito, Y., Suzuki, H., et al.
    • Organizer
      AGA Research Forum DDW2010
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Chronic infection with Helicobacter pylori induces downregulation of muscle-specific microRNAs and smooth muscle hypertrophy of the mouse stomach.2010

    • Author(s)
      Saito, Y., Suzuki, H., et al
    • Organizer
      AGA Research Forum DDW2010
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Induction of H. pylori resistance to metronidazole through enhanced expression of a bacterial efflux pump2010

    • Author(s)
      Tsugawa, H., Suzuki, H.Saito, Y., et al
    • Organizer
      AGA Research Forum DDW2010
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] The role of the Ferric uptake regulator (Fur) in Helicobacter pylori resistance to metronidazole.2010

    • Author(s)
      Tsugawa, H., Suzuki, H., Saito, Y., et al.
    • Organizer
      AGA Research Forum DDW2010
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Caudal-related homeobox 2 (Cdx2) suppresses stratification of esophageal squamous epithelial cells by down-regulating microRNA-221/2222010

    • Author(s)
      Matsuzaki, J., Suzuki, H., Saito, Y., et al.
    • Organizer
      DDW2010
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Downregulation of the tumor suppressor microRNA-29cplays a critical role in the progression of human gastric cancer.2010

    • Author(s)
      Saito, Y., Suzuki, H., et al.
    • Organizer
      DDW2010
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Final Research Report
  • [Book] eBook: Helicobacter pylori : a worldwide perspective 20122013

    • Author(s)
      Hidekazu Suzuki
    • Publisher
      Bentham Science Publishers
    • Related Report
      2012 Annual Research Report
  • [Book] eBook: OXIDATIVE STRESS AND DIETARY ANTIOXIDANTS2013

    • Author(s)
      Hidekazu Suzuki
    • Publisher
      Academic Press
    • Related Report
      2012 Annual Research Report
  • [Book] ヘリコバクターピロリ感染症の徹底検証2012

    • Author(s)
      鈴木秀和編集
    • Total Pages
      93
    • Publisher
      ライフ・サイエンス社
    • Related Report
      2011 Annual Research Report
  • [Book] Free Radical Biology in Digestive Diseases2011

    • Author(s)
      Suzuki, H., Nishizawa, T., Tsugawa, H., Hibi, T.(eds.) Naito, Y., Suematsu, M., Yoshikawa, T., Karger, Basel
    • Publisher
      Front. Gastrointest. Res.
    • Related Report
      2012 Final Research Report
  • [Book] Chapter 5: MicroRNAs in Gastric Cancer. MicroRNAs in Cancer Translational Research2011

    • Author(s)
      Suzuki, H., Saito, Y., Hibi, T.(eds.) William C.S. Cho
    • Publisher
      Springer
    • Related Report
      2012 Final Research Report
  • [Remarks] http://www.keio-med.jp/gastro/ugt/index.html

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      https://k-ris.keio.ac.jp/scripts/update/slogin.htm

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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