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Investigation of visual information transmission by retinal prosthesis

Research Project

Project/Area Number 22300188
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionOsaka University

Principal Investigator

MIYOSHI Tomomitsu  大阪大学, 医学(系)研究科(研究院), 助教 (70314309)

Co-Investigator(Kenkyū-buntansha) SAWAI Hajime  大阪大学, 医学系研究科, 准教授 (20202103)
Co-Investigator(Renkei-kenkyūsha) TAMURA Shinichi  大阪大学, 名誉教授 (30029540)
Project Period (FY) 2010-04-01 – 2013-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2012: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Keywords人工感覚器 / 人工網膜 / 電気刺激 / 機械学習 / 誘発電位 / 生理学 / 神経科学 / 機能評価 / リハビリテーション
Research Abstract

Evaluation of the cortical response evoked by retinal electrical stimulation is important to understand the information by prosthetic input to brain. However, previous studies analyzed cortical response mainly with field response or multi-unit response in relation to the visual topological map. In this study, electrophysiological response to retinal stimulation was recorded from the cat cerebral cortex and analyzed with mathematical methods. As the results, we were able to predict the stimulating retinal electrode from electrocorticogram dataset evoked by retinal stimulation with machine learning method. The accuracy of prediction may be improved by refinement of dataset preparation and increase of training dataset, although it was not so remarkable at this moment. This accuracy of prediction may be useful to evaluate electrodes and stimulating parameters of retinal prosthesis.

Report

(4 results)
  • 2013 Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (19 results)

All 2014 2013 2012 2010

All Journal Article (13 results) (of which Peer Reviewed: 6 results,  Open Access: 2 results) Presentation (6 results)

  • [Journal Article] Multiplexed spatiotemporal communication model in artificial neural networks2014

    • Author(s)
      Tamura S, Nishitani Y, Kamimura T, Hosokawa C, Miyoshi T, Sawai H, Mizuno-Matsumoyo Y, Chen Y-W
    • Journal Title

      Automation, Control and Intelligent Systems

      Volume: 1 Pages: 121-130

    • Related Report
      2013 Final Research Report
  • [Journal Article] Characteristics of retinal reflectance changes induced by transcorneal electrical stimulation in cat eyes2014

    • Author(s)
      Morimoto T, Kanda H, Miyoshi T, Hirohara Y, Mihashi T, Kitaguchi Y, Nishida K, Fujikado T
    • Journal Title

      PLoS ONE

      Volume: 9

    • Related Report
      2013 Final Research Report
  • [Journal Article] Multiplexed spatiotemporal communication model in artificial neural networks.2014

    • Author(s)
      Tamura, S., Nishitani, Y., Kamimura, T., Hosokawa, C., Miyoshi, T., Sawai, H., Mizuno-Matsumoyo, Y., CHen, Y-W.
    • Journal Title

      Automation, Control and Intelligent Systems

      Volume: 1 Issue: 6 Pages: 121-130

    • DOI

      10.11648/j.acis.20130106.11

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characteristics of retinal reflectance changes induced by transcorneal electrical stimulation in cat eyes2014

    • Author(s)
      Morimoto Takeshi, Kanda H, Miyoshi T, Hirohara Y, Mihashi T, Kitaguchi Y, Nishida K, Fujikado T
    • Journal Title

      PLOS ONE

      Volume: 9 Issue: 3 Pages: 1-11

    • DOI

      10.1371/journal.pone.0092186

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Spatiotemporal receptive field structures in retinogeniculate connections of cat2013

    • Author(s)
      Suematsu N, Naito T, Miyoshi T, Sawai H, Sato H
    • Journal Title

      Frontiers in System Neuroscience

      Volume: 7 Pages: 103-103

    • Related Report
      2013 Final Research Report
  • [Journal Article] Spatiotemporal receptive field structures in retinogeniculate connections of cat2013

    • Author(s)
      Suematsu N, Naito T, Miyoshi T , Sawai H, Sato H
    • Journal Title

      Frontiers in Systems Neuroscience

      Volume: 7 Pages: 1-13

    • DOI

      10.3389/fnsys.2013.00103

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical trial of chronic implantation of suprachoroidal-transretinal stimulation system for retinal prosthesis2012

    • Author(s)
      Fujikado T, Kamei M, Sakaguchi H, Kanda H, Morimoto T, Ikuno Y, Nishida K, Kishima H, Maruo T, Sawai H, Miyoshi T, Osawa K, Ozawa M
    • Journal Title

      Sensors and Materials

      Volume: 24 Pages: 181-187

    • Related Report
      2013 Final Research Report
  • [Journal Article] Detection of m-sequences from spike sequence in neuronal networks2012

    • Author(s)
      Nishitani Y, Hosokawa C, Mizuno-Matsumoto Y, Miyoshi T, Sawai H, Tamura S
    • Journal Title

      Computational Intelligence and Neuroscience

      Volume: Volume 2012(Article ID 862579)

    • Related Report
      2013 Final Research Report
  • [Journal Article] Random bin for analyzing neuron spike trains2012

    • Author(s)
      Tamura S, Miyoshi T, Sawai H, Mizuno-Matsumoto Y
    • Journal Title

      Computational Intelligence and Neuroscience

      Volume: Volume 2012(Article ID 153496)

    • Related Report
      2013 Final Research Report
  • [Journal Article] 網膜の情報処理2012

    • Author(s)
      三好智満
    • Journal Title

      Clinical Neuroscience

      Volume: 30 Pages: 887-889

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
  • [Journal Article] Clinical trial of chronic implantation of suprachoroidal-transretinal stimulation system for retinal prosthesis.2012

    • Author(s)
      Fujikado T, Kamei M, Sakaguchi H, Kanda H, Morimoto T, Ikuno Y, Nishida K, Kishima H, Maruo T, Sawai H, Miyoshi T, Osawa K, Ozawa M.
    • Journal Title

      Sensors and Materials

      Volume: 24 Pages: 181-187

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of M-Sequences from Spike Sequence in Neuronal Networks2012

    • Author(s)
      Nishitani Y, Hosokawa C, Mizuno-Matsumoto Y, Miyoshi M, Sawai H, Tamura S
    • Journal Title

      Computational Intelligence and Neuroscience

      Volume: 2012 Pages: 1-9

    • DOI

      10.1155/2012/862579

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Random bin for analyzing neuron spike trains.2012

    • Author(s)
      Tamura S, Miyoshi T, Sawai H, Mizuno-Matsumoto Y.
    • Journal Title

      Computational Intelligence and Neuroscience

      Volume: Volume 2012 Pages: 1-11

    • DOI

      10.1155/2012/153496

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Mechanism of receptive field generation in early visual pathway : simultaneous recording of retinal ganglion cells and lateral geniculate cells2014

    • Author(s)
      Miyoshi T. et al
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島
    • Related Report
      2013 Final Research Report
  • [Presentation] Mechanism of receptive field generation in early visual pathway: simultaneous recording of retinal ganglion cells and lateral geniculate cells.2014

    • Author(s)
      Miyoshi, T., Suematsu, N., Naito, T., Sawai, H., Sato, H.
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島
    • Related Report
      2012 Annual Research Report
  • [Presentation] 他脈絡膜上-経網膜刺激型人工網膜による反応の光学イメージング:閾値電流と埋植手術との関連2013

    • Author(s)
      三好智満
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] 脈絡膜上-経網膜刺激型人工網膜による反応の光学イメージング:閾値電流と埋植手術との関連2013

    • Author(s)
      三好智満
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
  • [Presentation] Intrinsic optical imaging of retinal response Transcorneal Electrical Stimulation2010

    • Author(s)
      Miyoshi T. et al
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Related Report
      2013 Final Research Report
  • [Presentation] Intrinsic optical imaging of retinal response Transcorneal Electrical Stimulation2010

    • Author(s)
      Miyoshi T., et al.
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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