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Interaction in peripheral reflexes -Individual difference and training effects

Research Project

Project/Area Number 22300213
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionUniversity of Tsukuba

Principal Investigator

NISHIYASU Takeshi  筑波大学, 体育系, 教授 (90237751)

Co-Investigator(Kenkyū-buntansha) HONDA Yasushi  筑波大学, 体育系, 教授 (20165616)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2012: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2011: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
Keywords筋代謝受容器 / 動脈圧反射 / ハンドグリップ運動 / 筋代謝需要器 / 筋代謝受容器反射 / 下肢運動負荷装置 / 心臓副交感神経 / 運動後阻血 / 超音波ドップラー法 / 周波数領域解析
Research Abstract

It was hypothesized that both muscle metaboreflex and arterial barorefelx contribute to regulate the heart rate and blood pressure during exercise and then the two reflexes were interplayed. This study investigated how the interplays changes in the different stimulus levels in muscle metaboreflex and in the different muscles activated (forearm and calf). Further, it was investigated whether the interplays change by the specific exercise training.
1) The increases in heart parasympathetic activity and the sensitivity of the arterial baroreflex on heart rate change (BRS) do not occur with the weak activation of muscle metaboreflex and do occur the above the threshold activation. Above the threshold, there is no gradual increase in heart parasympathetic activity and BRS.
2) The responses in heart parasympathetic activity and BRS during activation of the muscle metaboreflex are different between the different muscles activated.
3) The function of the muscle metaboreflex induced by handgrip exercise is not changed by the specific exercise training in competitive Badminton players.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (36 results)

All 2013 2012 2011 2010 Other

All Journal Article (17 results) (of which Peer Reviewed: 17 results) Presentation (19 results) (of which Invited: 1 results)

  • [Journal Article] Changes in arterial blood pressure elicited by severe passive heating at rest is associated with hyperthermia-induced hyperventilation in humans2013

    • Author(s)
      Fujii N, Ichinose M, Honda Y, Tsuji B, Watanabe K, Kondo N, Nishiyasu T.
    • Journal Title

      Eur J Appl Physiol

      Volume: 113(1) Pages: 51-62

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Arterial baroreflex control of muscle sympathetic nerve activity under orthostatic stress in humans.2012

    • Author(s)
      Ichinose M, Nishiyasu T.
    • Journal Title

      Front Physiol.

      Volume: 3 Pages: 314-314

    • DOI

      10.3389/fphys.2012.00314

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cardiovascular regulation during exercise -contribution of peripheral reflexes2012

    • Author(s)
      Ichinose M, Watanabe K, Fujii N, Nishiyasu T.
    • Journal Title

      J Phys Fitness Sports Med

      Volume: 1(2) Pages: 437-445

    • NAID

      10031158974

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of initial core temperature on hyperthermic hyperventilation during prolonged submaximal exercise in the heat.2012

    • Author(s)
      Tsuji B, Honda Y, Fujii N, Kondo N, Nishiyasu T.
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol.

      Volume: 302(1)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationships between the extent of apnea-induced bradycardia and the vascular response in the arm and leg during dynamic two-legged knee extension exercise.2012

    • Author(s)
      Nishiyasu T, Tsukamoto R, Kawai K, Hayashi K, Koga S, Ichinose M.
    • Journal Title

      Am J Physiol Heart Circ Physiol.

      Volume: 302(3)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationships between the extent of apnea-induced bradycardia and the vascular response in the arm and leg during dynamic two-legged knee extension exercise.2012

    • Author(s)
      Nishiyasu T
    • Journal Title

      Am J Physiol Heart Circ Physiol.

      Volume: 302(3) Pages: 864-71

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cardiovascular regulation during exercise – contribution of peripheral reflexes2012

    • Author(s)
      Ichinose M
    • Journal Title

      J Phys Fitness Sports Med

      Volume: 1(2) Pages: 437-445

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationships between the extent of apnea-induced bradycardia and the vascular response in the arm and leg during dynamic two-legged knee extension exercise2012

    • Author(s)
      Nishiyasu T, Tsukamoto R, Kawai K, Hayashi K, Koga S, Ichinose M
    • Journal Title

      Am J Physiol Heart Circ Physiol. : 2012

      Volume: 302(3)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Short-term exercise-heat acclimation enhances skin vasodilation but not hyperthermic hyperpnea in humans exercising in a hot environment2012

    • Author(s)
      Fujii N, Honda Y, Ogawa T, Tsuji B, Kondo N, Koga S, Nishiyasu T
    • Journal Title

      Eur J Appl Physiol.

      Volume: 112(1) Pages: 295-307

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of initial core temperature on hyperthermic hyperventilation during prolonged submaximal exercise in the heat2012

    • Author(s)
      Tsuji B, Honda Y, Fujii N, Kondo N, Nishiyasu T
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol

      Volume: 302(1) Pages: 94-102

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of muscle metaboreflex function through graded reduction in forearm blood flow during rhythmic handgrip exercise in humans2011

    • Author(s)
      Ichinose M, Delliaux S, Watanabe K, Fujii N, Nishiyasu T.
    • Journal Title

      Am J Physiol Heart Circ Physiol.

      Volume: 301(2)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of muscle metaboreflex function through graded reduction in forearm blood flow during rhythmic handgrip exercise in humans2011

    • Author(s)
      Ichinose M, Delliaux S, Watanabe K, Fujii N, Nishiyasu T
    • Journal Title

      Am J Physiol Heart Circ Physiol.

      Volume: 301(2)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ect of CO_2 on the ventilatory sensitivity to rising body temperature during exerci2011

    • Author(s)
      Hayashi K, Honda Y, Miyakawa N, Fujii N, Ichinose M, Koga S, Kondo N, Nishiyasu T
    • Journal Title

      J Appl Physiol.

      Volume: 110(5) Pages: 1334-41

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Individual differences in the heart rate response to activation of the muscle metaboreflex in humans.2010

    • Author(s)
      Watanabe K, Ichinose M, Fujii N, Matsumoto M, Nishiyasu T.
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 299(5)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Individual differences in the heart rate response to activation of the muscle metaboreflex in humans.2010

    • Author(s)
      Watanabe K, Ichinose M, Fuji N, Matsumoto M, Nishiyasu T.
    • Journal Title

      Am J Physiol Heart Circ Physiol.

      Volume: 299(5)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effects of breathing a helium-oxygen gas mixture on maximal pulmonary ventilation and maximal oxygen consumption during exercisein acute moderate hypobaric hypoxia.2010

    • Author(s)
      Ogawa T, Calbet JA, Honda Y, Fujii N, Nishiyasu T.
    • Journal Title

      Eur J Appl Physiol.

      Volume: 110(4) Pages: 853-61

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-thermal modification of heat-loss responses during exercise inhumans.2010

    • Author(s)
      Kondo N, Nishiyasu T, Inoue Y, Koga S.
    • Journal Title

      Eur J Appl Physiol.

      Volume: 110(3) Pages: 447-58

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] バドミントン競技選手における血管内皮機能および反射性循環調節に関する研究-利き腕と非利き腕に着目して2012

    • Author(s)
      田原 麗衣,渡邊 和仁,一之瀬 真志,吹田 真士,前田 清司,西保 岳
    • Organizer
      第67回日本体力医学会
    • Place of Presentation
      岐阜
    • Year and Date
      2012-09-16
    • Related Report
      2012 Final Research Report
  • [Presentation] 動的足底屈運動時における下腿陰圧負荷が活動肢血流量および中心循環反応に及ぼす影響2012

    • Author(s)
      一之瀬真志、一之瀬智子、西保 岳
    • Organizer
      第67回日本体力医学会
    • Place of Presentation
      岐阜
    • Year and Date
      2012-09-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 自発的過換気による動脈血二酸化炭素分圧低下が高強度間欠的運動時のパフォーマンス及び呼吸代謝応答に及ぼす影響2012

    • Author(s)
      橋本 峻 、辻 文、藤井 直人、渡辺 和仁、西保 岳
    • Organizer
      第67回日本体力医学会
    • Place of Presentation
      岐阜
    • Year and Date
      2012-09-15
    • Related Report
      2012 Final Research Report
  • [Presentation] Thermal, respiratory, and cardiovascular integration during prolonged exercise in the heat2012

    • Author(s)
      Nishiyasu T. シンポジスト
    • Organizer
      The Systems Biology of Exercise: Cardio-respiratory and Metabolic Integration
    • Place of Presentation
      University of Leeds, Leeds, UK
    • Year and Date
      2012-08-16
    • Related Report
      2012 Final Research Report
  • [Presentation] Muscle Metaboreflex Modulates Dynamic Cardiovascular and Cerebrovascular Responses to Acute Hypotension in Humans2012

    • Author(s)
      Ichinose M, Watanabe K, Tsuji B, Nishiyasu T
    • Organizer
      ACSM
    • Place of Presentation
      San Francisco USA
    • Year and Date
      2012-06-02
    • Related Report
      2012 Final Research Report
  • [Presentation] 運動と環境適応とアロスタシス2011

    • Author(s)
      西保 岳、シンポジスト
    • Organizer
      脳・神経・内分泌から運動の意義を考える会
    • Place of Presentation
      下関
    • Year and Date
      2011-09-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 運動と環境適応とアロスタシス2011

    • Author(s)
      西保岳
    • Organizer
      脳・神経・内分泌から運動の意義を考える会
    • Place of Presentation
      下関生涯学習プラザ(山口県)
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 運動時の循環調節-末梢性反射調節の複合作用-、自律神経と循環~トレーニングで循環調節は変わるか~2011

    • Author(s)
      西保 岳、シンポジスト
    • Organizer
      第19回日本運動生理学会
    • Place of Presentation
      徳島
    • Year and Date
      2011-08-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 筋代謝受容器反射活性時における動脈圧受容器反射による心拍調節機能:活動部位の違いに着目して2011

    • Author(s)
      渡邊 和仁、一之瀬 真志、藤井 直人、西保 岳
    • Organizer
      第19回日本運動生理学会
    • Place of Presentation
      徳島
    • Year and Date
      2011-08-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 運動時の循環調節-末梢性反射調節の複合作用-、自律神経と循環~トレーニングで循環調節は変わるか~2011

    • Author(s)
      西保岳
    • Organizer
      第19回日本運動生理学会
    • Place of Presentation
      徳島大学(徳島県)
    • Year and Date
      2011-08-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Spontaneous baroreflex control of heart rate during graded activation of the muscle metaboreflex in humans2011

    • Author(s)
      Watanabe K,Ichinose M, Delliaux S,Fujii N, Nishiyasu T
    • Organizer
      14th International Conference on Environmental Ergonomics (ICEE)
    • Place of Presentation
      Nafplio, Greece
    • Year and Date
      2011-07-13
    • Related Report
      2012 Final Research Report
  • [Presentation] Spontaneous baroreflex control of heart rate during graded activation of the muscle metaboreflex in humans2011

    • Author(s)
      Watanabe K, Ichinose M, Delliaux S,Fujii N, Nishiyasu T
    • Organizer
      BBSRCJapanese Partnership Symposium
    • Place of Presentation
      Leeds, UK(at University of Leeds)
    • Year and Date
      2011-07-08
    • Related Report
      2012 Final Research Report
  • [Presentation] Spontaneous baroreflex control of heart rate during activation of the muscle metaboreflex in the forearm and calf in humans2011

    • Author(s)
      Watanabe K, Ichinose M, Fujii N, Tsuji B, Sugihara A, Niwa T, Nishiyasu T
    • Organizer
      16th Annual Congress of the European College of Sport Science (ECSS)
    • Place of Presentation
      Liverpool, UK
    • Year and Date
      2011-07-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Spontaneous baroreflex control of heart rate during activation of the muscle metaboreflex in the forearm and calf in humans2011

    • Author(s)
      Kazuhito Watanabe, Masashi Ichinose, Naoto Fujii, Bun Tsuji, Akira Sugihara, Takehiro Niwa, Takeshi Nishiyasu
    • Organizer
      16th Annual Congress of the European College of Sport Science (ECSS)
    • Place of Presentation
      Arena and convention centre (Liverpool, UK.)
    • Year and Date
      2011-07-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] Cardiac autonomic function and baroreflex control of heart rate during graded activation of muscle metaboreflex in humans.2010

    • Author(s)
      Watanabe K, Ichinose M, Fujii N, Nishiyasu T
    • Organizer
      6^<th> BAMIS Seminar
    • Place of Presentation
      Tsukuba, Japan
    • Year and Date
      2010-09-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 筋代謝受容器反射の活性レベルの差異が循環調節に及ぼす影響2010

    • Author(s)
      渡邊和仁、一之瀬真志、藤井直人、西保岳
    • Organizer
      第65回日本体力医学会
    • Place of Presentation
      千葉商科大学
    • Year and Date
      2010-09-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Thermal, respiratory, and cardiovascular integration during prolonged exercise in the heat

    • Author(s)
      Takeshi Nishiyasu
    • Organizer
      The Systems Biology of Exercise: Cardio-respiratory and Metabolic Integration
    • Place of Presentation
      Leeds, UK
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Muscle Metaboreflex Modulates Dynamic Cardiovascular and Cerebrovascular Responses to Acute Hypotension in Humans.

    • Author(s)
      Masashi Ichinose
    • Organizer
      The Systems Biology of Exercise: Cardio-respiratory and Metabolic Integration
    • Place of Presentation
      Leeds, UK
    • Related Report
      2012 Annual Research Report
  • [Presentation] 動的足底屈運動時における下腿陰圧負荷が活動肢血流量および中心循環反応に及ぼす影響

    • Author(s)
      一之瀬真志
    • Organizer
      第67回日本体力医学会
    • Place of Presentation
      長良川国際会議場、岐阜
    • Related Report
      2012 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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