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Control of body weight based on the interaction between energy metabolism and sleep

Research Project

Project/Area Number 22300233
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionUniversity of Tsukuba

Principal Investigator

KUMPEI Tokuyama  筑波大学, 体育系, 教授 (00207565)

Co-Investigator(Kenkyū-buntansha) SATOH Makoto  筑波大学, 医学医療系, 教授 (50242409)
NAGASAKA Shoichiro  自治医科大学, 医学部, 准教授 (00296112)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2012: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2010: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Keywordsヒューマン・カロリメータ / 肥満 / 睡眠 / 運動処方 / 生活習慣 / 食習慣 / 運動 / 睡眠時無呼吸 / 間接熱量測定
Research Abstract

Late evening meal delays onset of sleep, enhances average blood glucose over 24 h, but does not support that late evening meal reduces 24 h energy expenditure.Compared with exercise performed in the postprandial state, exercise performed in the post-absorptive state oxidized more fat and saved more carbohydrate in the body, without affecting 24 h energy expenditure. Nonexercise activity thermogenesis plays an important role in long-range negative correlation and hence long-term blood glucose control in healthy young adults. Thus difference in life style affect 24 h energy metabolism and sleep. Patients with sleep apnea syndrome oxidized less fat during sleep, and their energy expenditure was slightly higher than that of control subjects.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (27 results)

All 2013 2012 2011 2010 Other

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (10 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Lack of negative correlation in glucose dynamics by NEAT restriction in healthy adults.2013

    • Author(s)
      Ogata H, K.Nakamura, M.Sato, K. Tokuyama, S.Nagasaka, N.Ebine, K.Kiyono, Y.Yamamoto.
    • Journal Title

      Med Sci Sports Exerc

      Volume: 45巻 Pages: 60-6

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of exercise performed before or after breakfast on 24h fat oxidation.2013

    • Author(s)
      Shimada K, Y.Yamamoto, K.Iwayama, K.Nakamura, S.Yamaguchi, M.Hibi, Y.Nabekura, K.Tokuyama.
    • Journal Title

      Metabolism

      Volume: 63巻 Pages: 793-800

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver.2013

    • Author(s)
      Otoda T, T.Takamura, H.Misu, T.Ota, S. Murata, H.Hayashi, H.Takayama, A. Kikuchi, T.Kanamori, K.R.Shima, F.Lan, T.Takeda, S.Kurita, K.Ishikura, Y.Kita, K.Iwayama, K.Kato, M.Uno, Y.Takeshita, M.Yamamoto, K.Tokuyama, S.Iseki, K. Tanaka, S.Kaneko.
    • Journal Title

      Diabetes

      Volume: 62巻 Pages: 811-824

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of breakfast skipping on diurnal variation of energy metabolism and blood glucose.2013

    • Author(s)
      Kobayashi F
    • Journal Title

      Obesity Research and Clinical Practice

      Volume: 45 Issue: 3 Pages: e249-e257

    • DOI

      10.1016/j.orcp.2013.01.001

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of exercise performed before or after breakfast on 24h fat oxidation. Metabolism.2013

    • Author(s)
      Shimada K
    • Journal Title

      Metabolism

      Volume: 62 Issue: 6 Pages: 793-800

    • DOI

      10.1016/j.metabol.2012.12.008

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lack of negative correlation in glucose dynamics by NEAT restriction in healthy adults.2013

    • Author(s)
      Ogata H
    • Journal Title

      Med Sci Sports Exerc.

      Volume: 45 Issue: 1 Pages: 60-66

    • DOI

      10.1249/mss.0b013e31826c2dfc

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Human calorimetry: Energy expenditure and substrate utilization measurements using a respiratory chamber.2013

    • Author(s)
      Hibi M
    • Journal Title

      J Physical Fitness Sports Medicine.

      Volume: 2 Pages: 93-99

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The lack of long-range negative correlations in glucose dynamics is associated with worse glucose control in diabetes mellitus patients.2012

    • Author(s)
      Ogata H, K.Tokuyama, S.Nagasaka, T.Tsuchita, I.Kusaka, S.Ishibashi, H.Suzuki, N.Yamada, K.Hamano, K.Kiyono, Z.R.Struzik, Y.Yamamoto
    • Journal Title

      Metabolism

      Volume: 61巻 Pages: 1041-1050

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Exercise in a metabolic chamber - effects of exercise on 24 h fat oxidation.2012

    • Author(s)
      Iwayama K
    • Journal Title

      J Physical Fitness Sports Medicine.

      Volume: 1 Pages: 307-316

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The lack of long-range negative correlations in glucose dynamics is associated with worse glucose control in diabetes mellitus patients2012

    • Author(s)
      Ogata, H., Ktokuyama, S.nagasaka, T.Tsuchita, I.Kusaka, S.Ishibashi, H.Suzuki, N.Yamada, K.Hamano, K.Kiyono, Z.R.Struzik, Y.Yamamoto
    • Journal Title

      Metabolism

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute effect of late evening meal on diurnal variation of blood glucose and energy metabolism.2011

    • Author(s)
      Sato M, K.Nakamura, H.Ogata, A.Miyashita, S.Nagasaka, N.Omi, S.Yamaguchi, M.Hibi, T.Umeda, S.Nakaji, K.Tokuyama
    • Journal Title

      Obesity Research and Clinical Practice

      Volume: 5巻

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Acute effect of late evening meal on diurnal variation of blood glucose and energy metabolism2011

    • Author(s)
      SatoM., K.Nakamura, H.Ogata, A.Miyashita, S.Nagasaka, N.Omi, S.Yamaguchi, M.Hibi, T.Umeda, S.Nakaji, K.Tokuyama
    • Journal Title

      Obesity Research and Clinical Practice

      Volume: 8

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute effect of late evening meal on diurnal variation of bloodg lucose and energy metabolism2011

    • Author(s)
      M, Sato, S.Nagasaka, 他8名, K. Tokuyama.
    • Journal Title

      Obesity Research, Clinical Practice

      Volume: 印刷中

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 食べ方と肥満:食事の摂り方がエネルギー代謝に及ぼす影響.2010

    • Author(s)
      佐藤真樹、宮下愛未、徳山薫平
    • Journal Title

      筑波大学体育科学系紀要

      Volume: 33 Pages: 17-24

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin and adipoRl regulate PGC-la and mitochondria by Ca^<2>+ and AMPK/SIRTI.2010

    • Author(s)
      Iwabu, M., 他17名 K.Tokuyama, 他7名
    • Journal Title

      Nature 464 : 1313-1319, 2010

      Volume: 464 Pages: 1313-1319

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 就寝前の短波長光暴露が睡眠と代謝に及ぼす影響.2012

    • Author(s)
      萱場桃子、岩山海渡、緒形ひとみ、瀬谷友美、徳山薫平、佐藤誠
    • Organizer
      日本睡眠学会第37回定期学術集会
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] 早朝空腹時の運動は24時間エネルギー代謝に影響するか.2012

    • Author(s)
      岩山海渡、嶋田健士郎、山本ゆき、中村和照、山口幸子、日比壮信、鍋倉賢治、徳山薫平
    • Organizer
      第67回日本体力医学会大会
    • Place of Presentation
      岐阜市
    • Related Report
      2012 Final Research Report
  • [Presentation] 早朝空腹時の運動は24時間エネルギー代謝に影響するか2012

    • Author(s)
      岩山海渡
    • Organizer
      第67回日本体力医学会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Metabolic rate and fuel utilization during sleep.2011

    • Author(s)
      Tokuyama K, H.Ogata, F.Igawa, K.Iwayama, Y.Katayose, M.Satoh.
    • Organizer
      Recent Advances and Controversies in Measuring Energy Metabolism.
    • Place of Presentation
      Maastricht, Netherlands
    • Related Report
      2012 Final Research Report
  • [Presentation] Matutinal training promotes 24h fat oxidation.2011

    • Author(s)
      Shimada K, Y.Yamamoto, K.Nakamura, K.Iwayama, Y.Nabekura, S.Yamaguchi, M.Hibi, K.Tokuyama.
    • Organizer
      Recent Advances and Controversies in Measuring Energy Metabolism.
    • Place of Presentation
      Maastricht, Netherlands.
    • Related Report
      2012 Final Research Report
  • [Presentation] ヒューマンカロリメータを用いた安静時代謝に関する基礎的検討.2011

    • Author(s)
      緒形ひとみ, 小林芙美, 岩山海渡, 日比壮信, 田中茂穂, 徳山薫平.
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路島
    • Related Report
      2012 Final Research Report
  • [Presentation] Metabolic rate and fuel utilization during sleep2011

    • Author(s)
      Tokuyama, K., H.Ogata, F.Igawa, K.Iwayama, Y.Katayose, M.Satoh
    • Organizer
      Recent Advances and Controversies in Measuring Energy Metabolism
    • Place of Presentation
      Maastricht, Netherlands(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Matutinal training promotes 24h fat oxidation2011

    • Author(s)
      Shimada, K., Y.Yamamoto, K.Nakamura
    • Organizer
      Recent Advances and Controversies in Measuring Energy Metabolism
    • Place of Presentation
      Maastricht, Netherlands
    • Related Report
      2011 Annual Research Report
  • [Presentation] 睡眠と睡眠時エネルギー消費量2011

    • Author(s)
      徳山薫平、佐藤誠
    • Organizer
      第32回日本肥満学会・イブニングセミナー
    • Place of Presentation
      淡路夢舞台国際会議場(兵庫県)(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 朝食摂取の有無がエネルギー代謝と覚醒度に及ぼす影響2010

    • Author(s)
      小林芙美, 他4名、佐藤誠, 徳山薫平
    • Organizer
      第64回日本栄養・食料学会
    • Place of Presentation
      徳島
    • Year and Date
      2010-05-22
    • Related Report
      2010 Annual Research Report
  • [Book] スポーツ運動科学:バイオメカニクスと生理学2010

    • Author(s)
      総監訳:宮永豊、監訳:, 他3名、徳山薫平
    • Total Pages
      959
    • Publisher
      西村書店
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.taiiku.tsukuba.ac.jp/-tokuyama/

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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