| Budget Amount *help |
¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2012: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
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| Research Abstract |
Although the mitotic spindle is an established target for the cancer chemotherapy, current anti-cancer drugs led to the serious side-effects caused by the disturbance of the microtubule functions in post-mitotic cells. In this study, by the extensive expression study as well as the functional analysis, we identified the genes that were highly expressed in human cancers and the tumor growth were suppressed when their functions were inhibited. Our analysis demonstrated that these genes were potential targets for the cancer chemotherapy
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