Fusion Process of MEMS and Nanostructure using Programmable Self Assembl

• Project/Area Number: 22310081
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Microdevices/Nanodevices
• Research Institution: Kyoto University
• Principal Investigator: TABATA Osamu 京都大学, 大学院・工学研究科, 教授 (20288624)
• Co-Investigator(Kenkyū-buntansha): ENDO Masayuki 京都大学, 学内共同利用施設等, 助教授 (70335389)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000); Fiscal Year 2012: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000); Fiscal Year 2011: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000); Fiscal Year 2010: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
• Keywords: マイクロファブリケーション / ナノ構造作製 / 自己組織化 / DNA / MEMS / NEMS / セルフ・アセンブル / 原子間力顕微鏡 / 1分子イメージング / DNAナノ構造 / セルフアセンブル / 融合プロセス / ナノ構造

Research Abstract

Fundamental technology was developed to construct a system whichhas high order non-periodic nanoscale structure fused with MEMS. The nanoscale structure was fabricated by self-assembly of a DNA nanostructure constructed by DNA origami technology.

Research Products

• [Journal Article] Photo-controllable DNA Origami Nanostructures Assembling into Predesigned Multiorientational Patterns (2013)
  • Author(s): Y. Yang, M. Endo, K. Hidaka, H. Sugiyama
  • Journal Title: Guanine quartets: Structure and application Volume: 1 Pages: 73-85
  • DOI: 10.1039/9781849736954-00073
  • ISBN: 9781849734608
  • Peer Reviewed
• [Journal Article] Control of the two-dimensional crystallization of DNA origami with various loop arrangements (2013)
  • Author(s): A. Rajendran, M. Endo, K. Hidaka, H. Sugiyaia
  • Journal Title: Chem. Commun. Volume: 49 Issue: 7 Pages: 686-688
  • DOI: 10.1039/c2cc37257f
  • Peer Reviewed
• [Journal Article] DNA Origami : Synthesis and Self-Assembly (2012)
  • Author(s): A.Rajendran, M.Kndo, H.Sugiyama
  • Journal Title: Curr.Protoc.Nucleic Acid Chem. Volume: 48 Issue: 1
  • DOI: 10.1002/0471142700.nc1209s48
  • Peer Reviewed
• [Journal Article] Photo-controllable DNA Origami Nanostructures Assembling into Predesigned Multiorientational Patterns (2012)
  • Author(s): Y. Yang, M. Endo, K. Hidaka, H. Sugiyama
  • Journal Title: Journal of the American Chemical Society Volume: 134 Issue: 51 Pages: 20645-20653
  • DOI: 10.1021/ja307785r
  • Peer Reviewed
• [Journal Article] Single-Molecule Visualization of the Hybridization and Dissociation of Photoresponsive Oligonucleotides and Their Reversible Switching Behavior in a DNA Nanostructure (2012)
  • Author(s): M. Endo, Y. Yang, Y. Suzuki, K. Hidaka, H. Sugiyama
  • Journal Title: Angewandte Chemie, International Edition Volume: 51 Issue: 42 Pages: 10518-10522
  • DOI: 10.1002/anie.201205247
  • Peer Reviewed
• [Journal Article] Sequence-Selective Single-Molecule Alkylation with a Pyrrole-Imidazole Polyamide Visualized in a DNA Nanoscaffold (2012)
  • Author(s): T. Yoshidome, M. Endo, G. Kashiwazaki, K. Hidaka, T. Bando, H. Sugiyama
  • Journal Title: J. Am. Chem. Soc Volume: 134 Issue: 10 Pages: 4654-4660
  • DOI: 10.1021/ja209023u
  • Peer Reviewed
• [Journal Article] Transcription Regulation System Mediated by Mechanical Operation of DNA Nanostructure (2012)
  • Author(s): M. Endo, R. Miyazaki, T. Emura, K. Hidaka, H. Sugiyama
  • Journal Title: J. Am. Chem. Soc Volume: 134 Issue: 6 Pages: 2852-2855
  • DOI: 10.1021/ja2074856
  • Peer Reviewed
• [Journal Article] A DNA-based molecular motor that can navigate a network of tracks (2012)
  • Author(s): S Wickham, J Bath, Y Katsuda, M Endo, K Hidaka, H Sugiyama, AJ Turberfield
  • Journal Title: Nature Nanotech Volume: 7 Issue: 3 Pages: 169-173
  • DOI: 10.1038/nnano.2011.253
  • Peer Reviewed
• [Journal Article] Single-Molecule Analysis Using DNA Origami (2012)
  • Author(s): A.Rajendran, M.Enao, H.Sugiyama
  • Journal Title: Angew.Chem.Int.Ed. Volume: 51 Issue: 4 Pages: 874-890
  • DOI: 10.1002/anie.201102113
  • Peer Reviewed
• [Journal Article] Zinc-Finger Proteins for Site-Specific Protein Positioning on DNA-Origami Structures (2012)
  • Author(s): E.Nakata, FF Liew, C Uwatoko, S Kiyonaka, Y Mori, Y Katsuda, M Endo, H Sugiyama, T Morii
  • Journal Title: Angew Chem Int Ed Volume: 51 Issue: 10 Pages: 2421-2424
  • DOI: 10.1002/anie.201108199
  • Peer Reviewed
• [Journal Article] DNA Origami : Synthesis and Self-Assembly (2012)
  • Author(s): A.Rajendran, M.Endo, H.Sugiyama
  • Journal Title: Current Protocols in Nucleic Acids Chem Volume: 48
  • Peer Reviewed
• [Journal Article] Photo-cross-linking-assisted thermal stability of DNA origami structures and its application for higher-temperature self-assembly (2011)
  • Author(s): A.Rajendran, M.Endo, Y.Eatsuda, K.Hidaka, H.Sugiyama
  • Journal Title: J.Am.Chem.Soc. Volume: 133 Issue: 37 Pages: 14488-91
  • DOI: 10.1021/ja204546h
  • Peer Reviewed
• [Journal Article] Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold (2011)
  • Author(s): M. Endo, Y. Yang, T. Emura, K. Hidaka, H. Sugiyama
  • Journal Title: Chem. Commun Volume: 47 Issue: 38 Pages: 10743-10745
  • DOI: 10.1039/c1cc13984c
  • Peer Reviewed
• [Journal Article] Recent Progress of DNA origami technology (2011)
  • Author(s): M.Endo, H.Sugiyama
  • Journal Title: Current Protocols in Nucleic Acids Chem Volume: 45
  • Peer Reviewed
• [Journal Article] Programmed Two-Dimensional Self-Assembly of Multiple DNA Origami Jigsaw Pieces. (2011)
  • Author(s): A.Rajendran, M.Endo, Y.Katsuda, K.Hidaka, H.Sugiyama
  • Journal Title: ACS Nano Volume: 5 Pages: 665-671
  • Peer Reviewed
• [Journal Article] Two-dimensional DNA origami assemblies using a four-way connector. (2011)
  • Author(s): M.Endo, T.Sugita, A.Rajendran, Y.Katsuda, T.Emura, K.Hidaka, H.Sugiyama
  • Journal Title: Chemical Communications Volume: 47 Pages: 3213-3215
  • Peer Reviewed
• [Journal Article] A Closer Look at DNA Nanotechnology - A bridge between nanomaterials and a nanosystem- (2010)
  • Author(s): O. Tabata
  • Journal Title: IEEE Nanotechnology Magazine Volume: Vol.4 Issue: 4 Pages: 13-17
  • DOI: 10.1109/mnano.2010.938652
  • Peer Reviewed
• [Journal Article] A bridge between nanomaterials and a nanosystem (2010)
  • Author(s): Osamu Tabata
  • Journal Title: IEEE Nanotechnology Magazine Volume: 4 Pages: 13-17
  • Peer Reviewed
• [Journal Article] Programmed-Assembly System Using DNA Jigsaw Pieces. (2010)
  • Author(s): M.Endo, T.Sugita, Y.Katsuda, K.Hidaka, H.Sugiyama
  • Journal Title: Chemistry, A European Journal, , (2010). Volume: 16 Pages: 5362-5368
  • Peer Reviewed
• [Presentation] DNA origami assembly on patterned silicon by AFM based lithography (2013)
  • Author(s): T. Akishiba, N. Tamura, T. Ichii, Y. Hirai, K. Sugano, T. Tsuchiya, H. Sugimura, O. Tabata
  • Organizer: The 26th IEEE International Conference on Micro Electro Mechanical Systems
  • Place of Presentation: Taipei, Taiwan
• [Presentation] DNAナノ構造変換を利用した転写の制御 (2012)
  • Author(s): 遠藤政幸、宮崎亮次、江村智
  • Organizer: 日本化学会第92春季年会
  • Place of Presentation: 横浜市
  • Year and Date: 2012-03-28
• [Presentation] AuNPs conjugate DNA origami nanotubes for nanophotonic application (2012)
  • Author(s): S.Z.Kiss, D.S.Hautzinger, O.
  • Organizer: The 7th IEEE International Conference on
  • Place of Presentation: 京都市
  • Year and Date: 2012-03-08
• [Presentation] Temperature dependency of DNA origami self-assembly rate (2012)
  • Author(s): C.Huang, T.Akishiba, N.
  • Organizer: The 7th IEEE International Conference on
  • Place of Presentation: 京都市
  • Year and Date: 2012-03-08
• [Presentation] DNA Nanotechnology-Fusion of nanostructure and MEMS- (2012)
  • Author(s): 田畑修
  • Organizer: 日本学術会議174委員会
  • Place of Presentation: 京都市
  • Year and Date: 2012-03-02
• [Presentation] DNA nanotechnology to bridge MEMS and nanomaterial (2012)
  • Author(s): O.Tabata
  • Organizer: Guardian Angels Workshop
  • Place of Presentation: Paris, France
  • Year and Date: 2012-02-02
• [Presentation] AuNPs conjugate DNA origami nanotubes for nanophotonic application (2012)
  • Author(s): S. Z. Kiss, D. S. Hautzinger, O. Tabata, and J. G. Korvink
  • Organizer: The 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
  • Place of Presentation: Kyoto, Japan
• [Presentation] DNA as an engineering material (2012)
  • Author(s): Osamu Tabata
  • Organizer: The 6th IEEE Asia-Pacific Conference on Transducers and Micro-Nano Technology
  • Place of Presentation: Naanjing, China
  • Invited
• [Presentation] DNAナノテクノロジーを用いたナノ構造とMEMSの融合に向けて (2012)
  • Author(s): 田畑 修
  • Organizer: 平成24年度電気学会マイクロマシン・センサシステム部門総合研究会(マイクロマシン・センサシステム研究会
  • Place of Presentation: 京都大学
  • Invited
• [Presentation] Integration of Nanostructure with MEMS (2011)
  • Author(s): O. Tabata
  • Organizer: Arab Forum
  • Place of Presentation: Cairo, Egypt
  • Year and Date: 2011-12-29
• [Presentation] DNA Mediated fusion of MEMS and Nanostructure (2011)
  • Author(s): O.Tabata
  • Organizer: Japan-Taiwan Joint Workshop
  • Place of Presentation: 京都市
  • Year and Date: 2011-11-29
• [Presentation] DNAナノ構造体の生体反応への応用 (2011)
  • Author(s): 遠藤政幸
  • Organizer: 創剤フォーラム若手研究会シンポジウム
  • Place of Presentation: 京都市
  • Year and Date: 2011-11-19
• [Presentation] AFM-based Imaging of the Movement of Biomolecules in the Designed DNA (2011)
  • Author(s): 遠藤政幸
  • Organizer: 5th Annual Symposium on Nanobiotechnology, Seoul
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2011-11-17
• [Presentation] Designed DNA Nanostructures for Assembly, Functionalization, and (2011)
  • Author(s): 遠藤政幸
  • Organizer: POSTECH AMS Symposium on Nanotechnology
  • Place of Presentation: Pohang, Korea
  • Year and Date: 2011-11-16
• [Presentation] Direct Observation of DNA recombination in the DNA nanoscaffold (2011)
  • Author(s): M.Endo, Y.Katsuda, K.Ou, K.
  • Organizer: The 38th International Symposium on Nucleic Acid
  • Place of Presentation: 札幌市
  • Year and Date: 2011-11-09
• [Presentation] Integration of MEHS and DNA Origami for a Nanophotonic System Platform (2011)
  • Author(s): O.Tabata
  • Organizer: International Photonics and OptoElectronics
  • Place of Presentation: Wuhan, China
  • Year and Date: 2011-11-03
• [Presentation] Integration of MEMS and DNA Origami for a Nanophotonic System Platform (2011)
  • Author(s): O.Tabata
  • Organizer: 2011 Advanced Nanosystems and Nanomaterials
  • Place of Presentation: Wuhan, China
  • Year and Date: 2011-11-02
• [Presentation] Higher Order Nanosturucture Formation by DNA origami and integration (2011)
  • Author(s): O.Tabata
  • Organizer: Process Integration Symposium with Bio and Nano
  • Place of Presentation: 東京
  • Year and Date: 2011-10-18
• [Presentation] DNAナノマシーンの「分子運動の可視化 (2011)
  • Author(s): 遠藤政幸
  • Organizer: 第84回日本生化学会大会 シンポジウム1分子ロボ
  • Place of Presentation: 京都市
  • Year and Date: 2011-09-21
• [Presentation] DNAオリガミ上でのDNA分子の移動の精密な操作 (2011)
  • Author(s): 遠藤政幸、勝田陽介、日高久
  • Organizer: ケミカルバイオロジー学会第6回年会
  • Place of Presentation: 東京都
  • Year and Date: 2011-05-25
• [Presentation] Programmed assembly of DNA nanostructures using designed DNAorigami (2011)
  • Author(s): M.Endo, A.Rajendran, T.
  • Organizer: 8th Conference on the Foundations of Nanoscience
  • Place of Presentation: Utah、USA
  • Year and Date: 2011-04-19
• [Presentation] Configurable Assembly of DNA origami on MEMS by Microfluidic Device (2011)
  • Author(s): C. Huang, T. Saeki, M. Endo, H. Sugiyama, C.-H. Weng, G.-B. Lee, K. Sugano, T. Tsuchiya, and O. Tabata
  • Organizer: The 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
  • Place of Presentation: Kaohsiung, Taiwan
• [Presentation] Programmed self-assembly of DNA jigsaw pieces. (2010)
  • Author(s): M.Endo, H.Sugiyama
  • Organizer: 7th Conference on the Foundations of Nanoscience 2010
  • Place of Presentation: Snowbird, UT, USA
  • Year and Date: 2010-04-28
• [Presentation] DNAナノマシーンの操作と運動の可視化
  • Author(s): 遠藤 政幸
  • Organizer: 分子ロボティクス研究会
  • Place of Presentation: 京都大学
  • Invited
• [Presentation] DNA ナノ構造上でのDNA 組み換え反応の直接観察
  • Author(s): 遠藤 政幸、勝田 陽介、鈴木 勇輝、王 恵瑜、日高 久美、杉山 弘
  • Organizer: 日本ケミカルバイオロジー学会 第7回年会
  • Place of Presentation: 京都大学
• [Presentation] Direct visualization of single transcription on the designed DNA nanoscaffold
  • Author(s): Masayuki Endo
  • Organizer: 9th Conference on the Foundations of Nanoscience 2012
  • Place of Presentation: Snowbird, UT, USA
  • Invited
• [Remarks]
  • URL: http://www.nms.me.kyoto-u.ac.jp/
• [Remarks]
  • URL: http://www.icems.kyoto-u.ac.jp/j/ppl/grp/sugiyama.html
• [Remarks]
  • URL: http://www.nms.me.kyoto-u.ac.jp/research/Fabrication/
• [Remarks]
  • URL: http://kuchem.kyoto-u.ac.jp/chembio//research/dna.html