| Project/Area Number |
22310082
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Microdevices/Nanodevices
|
|---|
| Research Institution | Kyoto Pharmaceutical University |
|---|
Principal Investigator |
TAKADA Kanji 京都薬科大学, 薬学部, 教授 (30102106)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
ITO Yukako 京都薬科大学, 薬学部, 講師 (30278444)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2012: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
|
|---|
| Keywords | マイクロファブリケーション / マイクロナノデバイス / 感染症 / マイクロアレイ / 薬学 / 免疫学 / マイクロ・ナノデバイス |
|---|
| Research Abstract |
Two- and three-layered dissolving microneedles was loaded with ovalbumin (OA) at the acral and second portion of the needles. As 3-layered MNs delivered anitigen to Langerhans cells that localize in the epiderm, stronger immunological reaction was induced. On the other hand, the target site of tetanus toxoid was revealed to be the Langerhans cells distributed mainly in the skin epiderm.
|
Report
(4 results)
Research Products
(64 results)
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[Book] ワクチン2012
Author(s)
高田寛治
Total Pages
900
Publisher
技術情報協会
Related Report
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