| Project/Area Number |
22330205
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Experimental psychology
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| Research Institution | 公益財団法人東京都医学総合研究所 (2012)
Tokyo Metropolitan Organization for Medical Research (2010-2011) |
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Principal Investigator |
WATANABE Masataka 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 特任研究員 (50092383)
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| Co-Investigator(Kenkyū-buntansha) |
KODAMA Tohru 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 副参事研究員 (20195746)
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| Co-Investigator(Renkei-kenkyūsha) |
HONNDA Yoshiko 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 研究員 (50142154)
KOJIMA Takashi 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 主任研究員 (30225429)
SAKAGAMI Masamichi 玉川大学, 脳科学研究所, 教授 (10225782)
TSUTSUI Ken-ichiro 東北大学, 大学院・生命科学研究科, 准教授 (90396466)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2012: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2010: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Keywords | 生理的報酬 / 学習獲得的報酬 / 内発的報酬 / 線条体 / 前頭連合野 / ニューロン活動 / 神経伝達物質 / オペラント課題 |
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| Research Abstract |
As reinforcers that strengthen learned responses, there are three different kinds of rewards (physiological, learned and intrinsic). We showed that physiological or learned rewards have different significance on the monkey depending on the social or intrinsic context in relation to whether they are delivered in the competitive situation or not, and demonstrated that monkey prefrontal neurons responded differently to the reward depending on the social context. We also showed that the magnitude of dopamine release in the monkey prefrontal cortex differed depending on whether the reward was delivered during the learning situation or not.
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