Development of Health and Environment Checking Sensors Inspired from Biological Functions

• Project/Area Number: 22350028
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Inorganic chemistry
• Research Institution: Nagoya Institute of Technology
• Principal Investigator: MASUDA Hideki 名古屋工業大学, 工学研究科, 教授 (50209441)
• Co-Investigator(Kenkyū-buntansha): OZAWA Tomohiro 名古屋工業大学, 工学研究科, 准教授 (70270999) ; FUNAHASHI Yasuhiro 大阪大学, 理学研究科, 教授 (00321604) ; INOMATA Tomohiko 名古屋工業大学, 工学研究科, 助教 (40397493)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥19,760,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥4,560,000); Fiscal Year 2012: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2011: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2010: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
• Keywords: NOセンサー / VOCセンサー / 微生物センサー / 健康センサー / 環境センサー / 金属錯体 / 生物機構 / 生物機能

Research Abstract

By mimicking specific functions of biological systems using metal complexes, we developed NO sensor as health checking one and VOC and microbe sensors as environment checking one.

Research Products

• [Journal Article] Highly selective binding of nitric oxide by Co"' and Fe" complexes (2013)
  • Author(s): Z. Zhang, T. Suwabe, M. Ishikawa, Y. Funahashi, T. Inomata, T. Ozawa and H. Masuda
  • Journal Title: Dalton Trans Volume: 42(13) Pages: 4470-4478
  • Peer Reviewed
• [Journal Article] Preparation, Characterization, and Reactivity of Dinitrogen Molybdenum Complexes with Bis(diphenylphosphino)amine Derivative Ligands that Form a Unique 4-Membered P-N-P Chelate Ring (2013)
  • Author(s): Takahiko Ogawa, Yuji Kajita, Yuko Wasada-Tsutsui, Hiroaki Wasada, and Hideki Masuda
  • Journal Title: Inorg. Chem Volume: 52 Pages: 182-195
  • Peer Reviewed
• [Journal Article] Preparations of CoIII and FeIII Complexes Showing a Highly Selective Binding Ability for NO Molecule (2013)
  • Author(s): Zizheng Zhang, Tatsuya Suwabe, Mai Ishikawa, Yasuhiro Funahashi, Tomohiko Inomata, Tomohiro Ozawa, and Hideki Masuda
  • Journal Title: Dalton Trans Volume: 42 Pages: 4470-4478
  • Peer Reviewed
• [Journal Article] Characterization and Application of Ru2+ Complex with Square-Planar Quadridentate Ligand Containing Arylamines for Dye-Sensitized Solar Cells (2013)
  • Author(s): T. Inomata_, K. Yamamoto, Y. Funahashi, T. Ozawa, H. Masuda
  • Journal Title: Jpn. J. Apl. Phys Volume: 52
  • NAID: 210000141770
  • Peer Reviewed
• [Journal Article] Adsorption Behavior of Microbes on a QCM Chip Modified with an Artificial Siderophore-FeIII Complex (2012)
  • Author(s): T. Inomata, H. Eguchi, Y. Funahashi, T. Ozawa, and H. Masuda
  • Journal Title: Langmulr Volume: 28(2) Pages: 1611-1617
  • Peer Reviewed
• [Journal Article] Aggregation behavior of differently substituted Ru(II)-complex dyes as sensitizers for electrodeposited ZnO solar cells. (2012)
  • Author(s): Asdim, K. Ichinose, T. Inomata, H. Masuda, T. Yoshida
  • Journal Title: J. Photochem. Photobiol. A Volume: 242 Pages: 67-71
  • Peer Reviewed
• [Journal Article] A Ternary Ruthenium(II) 2,2’:6’,2”-Terpyridine Complex Having Intramolecular π-π Stacking Interaction with Ancillary Benzyl Groups of the Mixed Ligand (2012)
  • Author(s): T. Aoki, Y. Wasada-Tsutsui, T. Inomata, T. Ozawa, Y. Funahashi, and H. Masuda
  • Journal Title: J. Chem. Chem. Eng Volume: 6 Pages: 363-367
  • Peer Reviewed
• [Journal Article] Enantioselective Synthesis of Imidazolines with Quaternary Stereocenters by Organocatalytic Reaction of N-(Heteroarenesulfonyl)imines with Isocyanoacetates (2012)
  • Author(s): S. Nakamura, Y. Maeno, M. Ohara, A. Yamamura, Y. Funahashi, and N. Shibata
  • Journal Title: Org. Lett Volume: 14 Pages: 2960-2963
  • Peer Reviewed
• [Journal Article] Synthesis and Characterization of a (-Peroxido)dicopper(II) Complex with N,N’,N”-Triisopropyl-cis,cis-1,3,5-triaminocyclohexane (R3TACH, R = iPr): Selective Preparation of (-Peroxido)dicopper(II) and Bis(m-oxido)dicopper(III) Species Regulated by Substituent Groups (2012)
  • Author(s): Jun Matsumoto, Yuji Kajita, and Hideki Masuda
  • Journal Title: Eur. J. Inorg. Chem Volume: 2012 Pages: 4149-4158
  • Peer Reviewed
• [Journal Article] Creation of a Binuclear Purple Copper Site within a de novo Coiled coil Protein (2012)
  • Author(s): Daigo Shiga, Yasuhiro Funahashi, Hideki Masuda, Akihiro Kikuchi, Masanori Noda, Susumu Uchiyama, Kiichi Fukui, Kenji Kanaori, Yu Takano, Haruki Nakamura, Misato Kamei, and Toshiki Tanaka
  • Journal Title: Biochemistry Volume: 51 Pages: 7901-7907
  • Peer Reviewed
• [Journal Article] Enantioselective Synthesis of ACHTUNGTRENUNGAG-041R by using N-Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts (2012)
  • Author(s): Noriyuki Hara, Shuichi Nakamura, Masahide Sano, Ryota Tamura, Yasuhiro Funahashi, and Norio Shibata
  • Journal Title: Chem. Eur. J Volume: 18 Pages: 9276-9280
  • Peer Reviewed
• [Journal Article] Electrochemical and photophysical study in solution and on ruthenium(II) polypyridyl complexes containing thiophenylethynylphenanthrolines self-assembled on gold surfaces (2012)
  • Author(s): M. Shiotsuka, H. Kondo, T. Inomata, K. Sto, and H. Masuda
  • Journal Title: Chem. Lett. Volume: 41 Pages: 1417-1419
  • NAID: 10031126548
  • Peer Reviewed
• [Journal Article] Tunig the geometries of a de novo blue copper protein by axial interractions (2012)
  • Author(s): D. Shiga, Y. Hamano, M. Kamei, Y. Funahashi, H. Masuda, M. Sakaguchi, T. Ogura, and T. Tanaka
  • Journal Title: J. Biological Inorganic Chemistry, Volume: 17 Pages: 1025-1031
  • Peer Reviewed
• [Journal Article] Adsorption Behavior of Microbes on a QCM Chip Modified with an Artificial Siderophore-Fe3+ Complex (2012)
  • Author(s): T.Inomata, H.Eguchi, Y.Funahashi, T.Ozawa, H.Masuda
  • Journal Title: Langmuir, 28(2), 1611-1617 (2012) Volume: 28 Pages: 1611-1617
  • Peer Reviewed
• [Journal Article] Visible Light-induced catalytic Oxidation Using Zeolite Encapsul asting Two Distinct Metal Complexes (2011)
  • Author(s): T Inomata, Y Nagai, N. Ohata, Y. Funahashi, T. Ozawa, and H Masuda
  • Journal Title: Jpn. J. Appl. Phys Volume: 50
  • Peer Reviewed
• [Journal Article] Nitrile Hydration by Co(lll)Complex with Oxygenated S Atoms Inserted into Mesoporous Silica (2011)
  • Author(s): T. Ozawa, T, Shibayama, T.Yano, Y. Funahashi, and H. Masuda
  • Journal Title: Jpn. J. Appl. Phys. Volume: 50
  • Peer Reviewed
• [Journal Article] Visible Light-induced catalytic Oxidation Using Zeolite Encapsulating Two Distinct Metal Complexes (2011)
  • Author(s): T.Inomata, Y.Nagai, N.Ohata, Y.Funahashi, T.Ozawa, H.Masuda
  • Journal Title: Jpn.J.Appl.Phys. Volume: 50 Issue: 1S1 Pages: 01AJ03-01AJ03
  • DOI: 10.1143/jjap.50.01aj03
  • NAID: 210000138282
  • Peer Reviewed
• [Journal Article] Magnetostructural Properties of a Twisted Bis(m-hydroxo) Dicopper(II) Core and Its Relevance to Formation of an Active Dioxygen Intermediate (2011)
  • Author(s): Y.Funahashi, T.Toyama, K.Yoshii, T.Nishikawa, M.Kishida, Y.Kajita, T.Inomata, T.Ozawa, Y.Wasada-Tsutsui, H.Masuda
  • Journal Title: Jpn.J.Appl.Phys., 50, 01AJ07-1-4 (2011) Volume: 50 Issue: 1S1 Pages: 01AJ07-01AJ07
  • DOI: 10.1143/jjap.50.01aj07
  • Peer Reviewed
• [Journal Article] Simplified bicyclic cage-type molecule as a C3-symmetric host : X-ray and FTIR characterization of encapsulation of a nitrile molecule (2010)
  • Author(s): Takumi Higa, Masato Fukui Kensuke Fukui, Yoshiki Naganuma, Yuji Kajita, Tomohiko Inomata, Tomohiro Ozawa, Yasuhiro Funahashi, Hideki Masuda
  • Journal Title: J.Incl.Phenom.Chem. Volume: 66 Pages: 171-177
  • Peer Reviewed
• [Journal Article] A Square-planar Ni(II) Complex with an N2S2 Donor Set Similar to the Active Centre of Nickel-containing Superoxide Dismutase and Its Reaction with Superoxide (2010)
  • Author(s): Daisuke Nakane, Shin-ichi Kuwasako, Michiharu Tsuge, Minoru Kubo, Yasuhiro Funahashi, Tomohiro Ozawa, Takashi Ogura, Hideki Masuda
  • Journal Title: Chem.Commun. Volume: 46 Pages: 2142-2144
  • Peer Reviewed
• [Journal Article] A Square-planar Ni(II)Complex with an Asymmetric N2S2 Donor Set as a Model for the Active Site of Nickel-containing SOD : Structural Conversion Driven by Addition of a Strong Donor Ligand in the High Oxidation State (2010)
  • Author(s): Daisuke Nakane, Yasuhiro Funahashi, Tomohiro Ozawa, Hideki Masuda
  • Journal Title: Chem.Lett. Volume: 39 Pages: 344-346
  • Peer Reviewed
• [Journal Article] Synthesis and Crystal Structures of Iron(II) Dichloride Complexes with α-isosparteine, β-isosparteine and 2-methylsparteine (2010)
  • Author(s): Beata Jasiewicz, Takanori Inazumi, Yoshiyuki Inagaki, Yuko Wasada-Tsutsui, Yasuhiro Funahashi, Hideki Masuda
  • Journal Title: J.Molecular Structure Volume: 984 Pages: 176-181
  • Peer Reviewed
• [Journal Article] Creation of a Type I Blue Copper Site within a de Novo Coiled-Coil Protein Scaffold (2010)
  • Author(s): Hideki Masuda, Akihiro Kikuchi, Masayuki Oda, Masanori Noda, Susumu Uchiyama, Kiichi Fukui, Kenji Kanamori, Kunihiko Tajima, Yu Takano, Haruki Nakamura, Toshiki Tanaka
  • Journal Title: J.Amer.Chem.Soc Volume: 132 Pages: 18191-18198
  • Peer Reviewed
• [Presentation] Development of a high sensitive microbe sensor using artificial siderophore-modified Au substrate and nanoparticle (2013)
  • Author(s): T. Murase, T. Inomata, Y. Funahashi, T. Ozawa, H. Masuda
  • Organizer: 5th Interinational Symposium on Advanced Plasma Science and its Applications for Nitrides and Nanomaterials
  • Place of Presentation: Nagoya
• [Presentation] High sensitive VOCs sensor using a hydrophobic zeolite-based organic-inorganic hybrid compound suppressing moisture adsorption (2013)
  • Author(s): H. Yamawaki, Y. Taira, T. Inomata, Y. Funahashi, T. Ozawa, H. Masuda
  • Organizer: 5th Interinational Symposium on Advanced Plasma Science and its Applications for Nitrides and Nanomaterials
  • Place of Presentation: Nagoya
• [Presentation] Synthesis of a Fe(III)-N2O2 type complex with high NO selectivity (2013)
  • Author(s): M. Ishikawa, T. Suwabe, T. Inomata, Y, Funahashi, T. Ozawa, H. Masuda
  • Organizer: 5th Interinational Symposium on Advanced Plasma Science and its Applications for Nitrides and Nanomaterials
  • Place of Presentation: Nagoya
• [Presentation] 物質・エネルギー変換の未来を拓く高機能材料の開発 (2012)
  • Author(s): 増田秀樹
  • Organizer: 高分子学会ポリマーフロンティアサイエンス研究会
  • Place of Presentation: 東工大
  • Year and Date: 2012-04-13
• [Presentation] Density Functional Study of Binding of CO, NO, and O2 to Co-Centered N2S2 Coordination environment (2012)
  • Author(s): H. Wasada, Y. Wasada-Tsutsui, Z. Zizheng, T. Hashimoto, T. Yano, T. Inomata, Y. Funahashi, T. Ozawa, H. Masuda
  • Organizer: 14th International Congress of Quantum Chemistry
  • Place of Presentation: USA
• [Presentation] Four electron reduction of dioxygen by non-heme diiron(II) model complexes on gold electrode modified with an ionic liquid (2011)
  • Author(s): 増田秀樹
  • Organizer: France-Japan Coordination Chemistry Symposium
  • Place of Presentation: Rennes (France)
• [Presentation] Electro-chemical Reduction of Dioxygen by Diiron(II) Complex Modified-Gold Electrode in an Aqueous Media (2011)
  • Author(s): Hideki Masuda
  • Organizer: The 3^<rd> Japan-Korea Joint Symposium on Transition Metal Complexes
  • Place of Presentation: Okinawa
• [Presentation] Electro-chemical Reduction of Dioxygen by Diiron(II) Complex Modified-Gold Elctrode in an Aqueous Media (2011)
  • Author(s): Hideki Masuda
  • Organizer: IMS Symposium
  • Place of Presentation: Okazaki
• [Presentation] Electro-chemical Reduction of Dioxygen on Diiron(II) Complex Modified-Gold Elctrode in an Aqueous Media (2011)
  • Author(s): Hideki Masuda
  • Organizer: BMMP-11
  • Place of Presentation: 名古屋大学
• [Presentation] Design of Copper Complexes Activating Dioxygen Species as an Active Site Model of Copper-oxygenases (2010)
  • Author(s): Hideki Masuda
  • Organizer: PacifiChem2010
  • Place of Presentation: Hawaii
• [Presentation] 生物無機化学の挑戦 -分子認識・機能発現・デバイス化- (2009)
  • Author(s): 増田秀樹
  • Organizer: 第7回機能性分子シンポジウム
  • Place of Presentation: 筑波大学
  • Year and Date: 2009-10-31
• [Book] ケミカルエンジニアリング「健康・環境センサーの開発」 (2012)
  • Author(s): 増田秀樹、小澤智宏、猪股智彦
  • Publisher: 化学工業社
• [Book] ケミカルエンジニアリング (2012)
  • Author(s): 増田秀樹, 小澤智宏, 猪股智彦
  • Publisher: 健康・環境センサーの開発
• [Book] べ一シックマスター 無機化学 (2010)
  • Author(s): 増田秀樹、長嶋雲兵
  • Publisher: オーム社
• [Book] わかるXわかった無機化学 (2010)
  • Author(s): 齋藤勝裕、増田秀樹
  • Total Pages: 240
  • Publisher: オーム社
• [Book] ベーシックマスター無機化学 (2010)
  • Author(s): 増田秀樹、長嶋雲兵
  • Total Pages: 440
  • Publisher: オーム社
• [Remarks]
  • URL: http://www.ach.nitech.ac.jprinorg/masuda/Japanese/
• [Remarks]
• [Remarks]
  • URL: http://researcher.nitech.ac.jp/
• [Remarks]
  • URL: http://www.ach.nitech.ac.jp/~inorg/masuda/Japanese/index.html
• [Patent(Industrial Property Rights)] 人工シデロフォア錯体が修飾された微粒子、および当該微粒子が吸着したセンサー基板 (2013)
  • Inventor(s): 増田秀樹、小澤智宏、猪股智彦、村瀬貴範
  • Industrial Property Rights Holder: 名古屋工業大学
  • Filing Date: 2013-03-24
• [Patent(Industrial Property Rights)] Method for detecting low concentration gas (2013)
  • Inventor(s): 増田秀樹、猪股智彦、澤木啄
  • Industrial Property Rights Holder: 名古屋工業大学
  • Acquisition Date: 2013-02-05
  • Overseas
• [Patent(Industrial Property Rights)] 人工シデロフォア錯体が修飾された微粒子、および当該微粒子が被着したセンサー基板 (2013)
  • Inventor(s): 増田秀樹，小澤智宏、猪股智彦、村瀬貴範
  • Industrial Property Rights Holder: 増田秀樹，小澤智宏、猪股智彦、村瀬貴範
  • Industrial Property Rights Type: 特許
  • Filing Date: 2013-03-24
• [Patent(Industrial Property Rights)] 人工分子により修飾した走査型プローブ顕微鏡用探針、およびこれに用いる人工錯体分子 (2012)
  • Inventor(s): 増田秀樹、小澤智宏、猪股智彦、村瀬貴範
  • Industrial Property Rights Holder: 名古屋工業大学
  • Filing Date: 2012-12-28
• [Patent(Industrial Property Rights)] 人工分子により修飾した走査型プローブ顕微鏡用探針、およびこれに用いる人工錯体分子 (2012)
  • Inventor(s): 増田秀樹、小澤智宏、猪股智彦、村瀬貴範
  • Industrial Property Rights Holder: 増田秀樹、小澤智宏、猪股智彦、村瀬貴範
  • Industrial Property Rights Type: 特許
  • Filing Date: 2012-12-28
• [Patent(Industrial Property Rights)] 金属錯体内包ゼオライトの疎水化方法およびそれによって得られたセンサー (2011)
  • Inventor(s): 増田秀樹、猪股智彦、山脇大輝
  • Industrial Property Rights Holder: 名古屋工業大学
  • Filing Date: 2011-08-23
• [Patent(Industrial Property Rights)] イオン液体およびイオン液体修飾基材 (2011)
  • Inventor(s): 猪股智彦、北川竜也、船橋靖博、小澤智宏、増田秀樹
  • Industrial Property Rights Holder: 名古屋工業大学
  • Industrial Property Number: 2011-028243
  • Filing Date: 2011-02-14
• [Patent(Industrial Property Rights)] 金属錯体内包ゼオライトの疎水化方法およびそれによって得られたセンサー (2011)
  • Inventor(s): 猪股智彦, 山脇大輝, 増田秀樹
  • Industrial Property Rights Holder: 名古屋工業大学
  • Industrial Property Number: 2011-181036
  • Filing Date: 2011-08-23
• [Patent(Industrial Property Rights)] 高選択的NOセンシング素子 (2010)
  • Inventor(s): 増田秀樹、小澤智宏、舩橋靖博、猪股智彦、諏訪部達也
  • Industrial Property Rights Holder: 名古屋工業大学
  • Filing Date: 2010-06-25
• [Patent(Industrial Property Rights)] 高選択的NOセンシング素子 (2010)
  • Inventor(s): 増田秀樹、小澤智宏、舩橋靖博、猪股智彦、諏訪部達也
  • Industrial Property Rights Holder: 名古屋工業大学
  • Industrial Property Number: 2010-144463
  • Filing Date: 2010-06-25
• [Patent(Industrial Property Rights)] SOD活性亜鉛錯体類 (2010)
  • Inventor(s): 増田秀樹, 実川浩一郎, 和田章
  • Industrial Property Rights Holder: 名古屋工業大学
  • Acquisition Date: 2010-04-28
• [Patent(Industrial Property Rights)] ゼオライトを用いた抗菌剤 (2010)
  • Inventor(s): 増田秀樹 大畑奈弓
  • Industrial Property Rights Holder: 名古屋工業大学
  • Acquisition Date: 2010-12-17