Development of imaging materials utilizing near-infrared luminescence of lanthanide complex

• Project/Area Number: 22350065
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Functional materials chemistry
• Research Institution: Osaka City University
• Principal Investigator: SHINODA Satoshi 大阪市立大学, 大学院・理学研究科, 教授 (00285280)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥14,430,000 (Direct Cost: ¥11,100,000、Indirect Cost: ¥3,330,000); Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2011: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2010: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
• Keywords: 分子認識 / 近赤外発光 / 希土類錯体 / 近赤外光 / イメージング / 多核錯体 / タンパク質 / センシング / 水溶性 / エネルギー移動 / 希土類 / 生体アニオン / アミノ酸 / ライブラリー / らせん構造

Research Abstract

Multinuclear complexes containing lanthanide ions and transition metal ions were synthesized, and anion recognition and sensitized near-infrared lanthanide luminescence were realized with these complexes by utilizing characteristic properties of both meta

Research Products

• [Journal Article] Dynamic Cyclen-Metal Complexes for Molecular Sensing and Chirality Signaling (2013)
  • Author(s): S. Shinoda
  • Journal Title: Chem. Soc. Rev. Volume: 42 Issue: 4 Pages: 1825-1835
  • DOI: 10.1039/c2cs35295h
  • Peer Reviewed
• [Journal Article] Induced Circular-Dichroism Chirality Probes for Selective Amino Acid Detection through Screening of a Dynamic Combinatorial Library of Lanthanide Complexes (2012)
  • Author(s): S. Shinoda, K. Terada, and H. Tsukube
  • Journal Title: Chem.-Asian J. Volume: 7 Issue: 2 Pages: 400-405
  • DOI: 10.1002/asia.201100618
  • Peer Reviewed
• [Journal Article] Ytterbium-Substituted Transferrin and Lactoferrin for Near-Infrared Luminescent pH Indication (2012)
  • Author(s): S. Shinoda, K. Terada, M. Eiraku Masaki, Y. Kataoka, and H. Tsukube
  • Journal Title: New J. Chem. Volume: 36 Issue: 8 Pages: 1545-1547
  • DOI: 10.1039/c2nj40201g
  • Peer Reviewed
• [Journal Article] Development of Analytical and Separation Systems Using Ternary Complexation Characteristics of Tris(β-diketonato)lanthanides (2012)
  • Author(s): 篠田哲史,築 部 浩
  • Journal Title: BUNSEKI KAGAKU Volume: 61 Issue: 3 Pages: 169-176
  • DOI: 10.2116/bunsekikagaku.61.169
  • NAID: 10030135215
  • ISSN: 0525-1931
  • Peer Reviewed
• [Journal Article] トリス(β-ジケトナト)ランタノイド錯体の三元錯体形成特性を活用する分離分析システムの構築(review) (2012)
  • Author(s): 篠田哲史、築部浩
  • Journal Title: 分析化学(Bunseki Kagaku) Volume: 61 Pages: 169-176
  • Peer Reviewed
• [Journal Article] Dynamically Capped Rotaxanes: Metal Coordination vs. Acid-Base Pairing in the Chiral End-Capping (2011)
  • Author(s): S. Shinoda, T. Maeda, H. Miyake, and H. Tsukube
  • Journal Title: Supramol. Chem. Volume: 23 Issue: 3-4 Pages: 244-248
  • DOI: 10.1080/10610278.2010.521838
  • Peer Reviewed
• [Journal Article] Luminescent Double-Decker Type Guanine Octets with Trivalent Lanthanide Cations: In situ Self-Assembling and Stability Evaluation in Homogeneous Organic Media (2011)
  • Author(s): S. Shinoda, T. Noguchi, M. Ikeda, Y. Habata, and H. Tsukube
  • Journal Title: J. Inclusion Phenom. Macrocycl. Chem. Volume: 71 Issue: 3-4 Pages: 523-527
  • DOI: 10.1007/s10847-011-9937-2
  • Peer Reviewed
• [Journal Article] Mixed-Metal Complexes Incorporating Platinum and Lanthanide Centers for Selective Binding and Chirality Sensing of Succinates (2011)
  • Author(s): S. Shinoda, A. Mizote, M. Eiraku Masaki, M. Yoneda, H. Miyake, and H. Tsukube
  • Journal Title: Inorg. Chem. Volume: 50 Issue: 13 Pages: 5876-5878
  • DOI: 10.1021/ic200853u
  • Peer Reviewed
• [Journal Article] Luminescent lanthanide complexes as analytical tools in anion sensing, pH indication and protein recognition (2011)
  • Author(s): S. Shinoda and H. Tsukube
  • Journal Title: Analyst Volume: 136 Issue: 3 Pages: 431-435
  • DOI: 10.1039/c0an00808g
  • Peer Reviewed
• [Journal Article] Luminescent Lanthanide Complexes as Analytical Tools in Anion Sensing, pH Indication and Protein Recognition (2011)
  • Author(s): S.Shinoda, H.Tsukube
  • Journal Title: Analyst Volume: 136 Pages: 431-435
  • Peer Reviewed
• [Journal Article] Combinatorial Screening of Lanthanide Complex Library for Luminescence Sensing of Amino Acids (2010)
  • Author(s): S. Shinoda, K. Yano, and H. Tsukube
  • Journal Title: Chem. Commun. Volume: 46 Issue: 18 Pages: 3110-3112
  • DOI: 10.1039/c000542h
  • Peer Reviewed
• [Journal Article] 希土類錯体の近赤外発光を利用した基質センシング (2010)
  • Author(s): 篠田哲史
  • Journal Title: 光化学 Volume: 41 Pages: 140-143
  • NAID: 10027623449
  • URL: http://photochemistry.jp/journal_j/index.htm
  • Peer Reviewed
• [Journal Article] Combinatorial Screening of Lanthanide Complex Library for Luminescence Sensing of Amino Acids (2010)
  • Author(s): S.Shinoda, K.Yano, H.Tsukube
  • Journal Title: Chem.Commun. Volume: 46 Pages: 3110-3112
  • Peer Reviewed
• [Journal Article] Luminescent Double-Decker Type Guanine Octets with Trivalent Lanthanide Cations
  • Author(s): S.Shinoda, T.Noguchi, M.Ikeda, Y.Habata, H.Tsukube
  • Journal Title: J.Inclusion Phenom.Macrocycl.Chem. Volume: (印刷中)
  • Peer Reviewed
• [Presentation] 近赤外発光 pH 指示薬としてのイッテルビウム置換トランスフェリンおよびラクトフェリン第28回近赤外フォーラム (2013)
  • Author(s): 篠田哲史
  • Organizer: 第28回近赤外フォーラム
  • Place of Presentation: 沖縄, 日本
• [Presentation] イッテルビウム錯体の光反応を利用したドーパミンの近赤外発光検出 (2013)
  • Author(s): 篠田哲史, 徳田千晴
  • Organizer: 第28回近赤外フォーラム
  • Place of Presentation: 沖縄, 日本
• [Presentation] キレート配位子と希土類イオンによるライブラリーを用いた芳香族アミノ酸の発光センシング (2012)
  • Author(s): 篠田哲史, 徳田千晴, 築部浩
  • Organizer: 日本化学会第92春季年会
  • Place of Presentation: 慶応大学(神奈川県)
  • Year and Date: 2012-03-25
• [Presentation] サイクレン-希土類錯体の不斉配位化学を活用したグリシン誘導体アニオンへのキラリティー転写 (2012)
  • Author(s): 安枝裕貴, 篠田哲史, 築部浩
  • Organizer: 日本化学会第92春季年会
  • Place of Presentation: 慶応大学(神奈川県)
  • Year and Date: 2012-03-25
• [Presentation] Zn(II) Porphyrin-Appended Lanthanide Complex as a Dual Emissive Molecular Sensor (2012)
  • Author(s): S. Shinoda and S. Sakai
  • Organizer: International Symposium on Rare Earths 2012 in Okinawa for the 30th Anniversary of The Rare Earth Society of Japan
  • Place of Presentation: 沖縄, 日本
• [Presentation] Chirality Transfer between a Lanthanide Complex and a Carboxylate Anion on Ternary Complexation (2012)
  • Author(s): S. Shinoda, Y. Yasueda, H. Miyake, and H. Tsukube
  • Organizer: 8th International Conference on f-Elements
  • Place of Presentation: ウディネ, イタリア
• [Presentation] サイクレン-希土類錯体とカルボン酸アニオン間の相互キラリティー転写 (2012)
  • Author(s): 安枝裕貴, 篠田哲史, 三宅弘之, 築部 浩
  • Organizer: 第29回希土類討論会
  • Place of Presentation: 札幌, 日本
• [Presentation] キレート配位子と希土類イオンによるライブラリーを用いた芳香族アミノ酸の発光センシング (2012)
  • Author(s): 篠田哲史, 徳田千晴, 築部 浩
  • Organizer: 日本化学会第92 春季年会
  • Place of Presentation: 横浜, 日本
• [Presentation] サイクレン-希土類錯体の不斉配位化学を活用したグリシン誘導体アニオンへのキラリティー転写 (2012)
  • Author(s): 安枝裕貴, 篠田哲史, 築部 浩
  • Organizer: 日本化学会第92春季年会
  • Place of Presentation: 横浜, 日本
• [Presentation] タンパク-希土類錯体の近赤外発光による水溶液のpHセンシング (2011)
  • Author(s): 篠田哲史, 寺田径子, 築部浩
  • Organizer: 第27回近赤外フォーラム
  • Place of Presentation: 文部科学省研究交流センター(茨木県)
  • Year and Date: 2011-11-11
• [Presentation] Luminescent Lanthanide Complexes as Analytical Tools (2011)
  • Author(s): S.Shinoda
  • Organizer: 3rd Asian Conference on Coordination Chemistry
  • Place of Presentation: New Delhi, India(招待講演)
  • Year and Date: 2011-10-19
• [Presentation] 希土類イオンに置換したトランスフェリン類によるアニオンの発光センシング (2011)
  • Author(s): 篠田哲史, 正木深雪, 寺田径子, 築部浩
  • Organizer: 第5回バイオ関連化学シンポジウム
  • Place of Presentation: つくば国際会議場(茨城県)
  • Year and Date: 2011-09-13
• [Presentation] Two-Step Chirality Induction on Metal-Cyclen Complexes (2011)
  • Author(s): H.Ito, S.Shinoda, H.Tsukube
  • Organizer: 23rd International Symposium on Chiral Discrimination
  • Place of Presentation: Livapool, UK
  • Year and Date: 2011-07-12
• [Presentation] Luminescence and Circular Dichroism Sensing of Anionic Substrates in Aqueous Solutions (2011)
  • Author(s): S.Shinoda, H.Tsukube
  • Organizer: 23th Rare Earth Research Conference
  • Place of Presentation: Santa Fe, New Mexico, USA(招待講演)
  • Year and Date: 2011-06-22
• [Presentation] サイクレンー希土類錯体による水中でのキラリティースイッチング (2011)
  • Author(s): 篠田哲史, 御前仁美, 築部浩
  • Organizer: モレキュラー・キラリティー2011
  • Place of Presentation: 東京工業大学(東京都)
  • Year and Date: 2011-05-21
• [Presentation] TPEN型6座配位子と硝酸ランタン(III)との錯体形成:実験化学と計算化学の融合 (2011)
  • Author(s): 篠田哲史, 御前仁美, 矢野径子, 築部浩, 松田彩, 森寛敏
  • Organizer: 第28回希土類討論会
  • Place of Presentation: タワーホール船堀(東京都)
  • Year and Date: 2011-05-12
• [Presentation] タンパク-希土類錯体の近赤外発光による水溶液のpHセンシング (2011)
  • Author(s): 篠田哲史, 寺田径子, 築部 浩
  • Organizer: 第27回近赤外フォーラム
  • Place of Presentation: 東京, 日本
• [Presentation] Luminescent Lanthanide Complexes as Analytical Tools (2011)
  • Author(s): S. Shinoda
  • Organizer: 3rd Asian Conference on Coordination Chemistry
  • Place of Presentation: ニューデリー, インド
• [Presentation] 希土類イオンに置換したトランスフェリン類によるアニオンの発光センシング (2011)
  • Author(s): 篠田哲史, 正木深雪, 寺田径子, 築部 浩
  • Organizer: 第5回バイオ関連化学シンポジウム
  • Place of Presentation: つくば, 日本
• [Presentation] Luminescence and Circular Dichroism Sensing of Anionic Substrates in Aqueous Solutions (2011)
  • Author(s): S. Shinoda and H. Tsukube
  • Organizer: 23th Rare Earth Research Conference
  • Place of Presentation: サンタフェ, アメリカ
• [Presentation] サイクレンー希土類錯体による水中でのキラリティースイッチング (2011)
  • Author(s): 篠田哲史, 御前仁美, 築部 浩
  • Organizer: モレキュラー・キラリティー2011
  • Place of Presentation: 東京, 日本
• [Presentation] アニオンの配位を利用した希土類錯体キラリティーのスイッチング (2011)
  • Author(s): 篠田哲史, 御前仁美, 築部 浩
  • Organizer: 日本化学会第91回春季年会
  • Place of Presentation: 日本
• [Presentation] 9 配位希土類錯体の発光および円二色性のpH依存性 (2011)
  • Author(s): 篠田哲史, 安枝裕貴, 築部 浩
  • Organizer: 日本化学会第91回春季年会
  • Place of Presentation: 日本
• [Presentation] 9配位希土類錯体の発光および円二色牲のpH依存性 (2011)
  • Author(s): 篠田哲史, 安枝裕貴, 築部浩
  • Organizer: 日本化学会第91回春季年会
  • Place of Presentation: 神奈川大学、横浜市、神奈川県
• [Presentation] キレート型6座配位子を有する希土類錯体の発光特性とアミノ酸センシング (2011)
  • Author(s): 篠田哲史, 矢野径子, 築部浩
  • Organizer: 日本化学会第91回春季年会
  • Place of Presentation: 神奈川大学、横浜市、神奈川県
• [Presentation] 希土類錯体の近赤外発光を利用したアミノ酸のセンシング (2010)
  • Author(s): 篠田哲史, 矢野径子, 築部 浩
  • Organizer: 第26回近赤外フォーラム
  • Place of Presentation: 東京, 日本
• [Presentation] Chirality Induction and Enhanced Near-Infrared Luminescence of Cyclen-Lanthanide Complexes by Chiral Carboxylate Anions (2010)
  • Author(s): S. Shinoda, H. Misaki, and H. Tsukube
  • Organizer: Molecular Sensors and Molecular Logic Gates (MSMLG-2010)
  • Place of Presentation: アンタリア, トルコ
• [Presentation] pHに応答した希土類錯体のキラリティー発現および発光増大 (2010)
  • Author(s): 篠田哲史, 御前仁美, 安枝裕貴, 築部 浩
  • Organizer: 第60回錯体化学討論会
  • Place of Presentation: 大阪, 日本
• [Presentation] Near-Infrared Luminescence Sensing of Biological Substrates Based on Lanthanide Coordination Chemistry (2010)
  • Author(s): S. Shinoda
  • Organizer: First International Conference on Luminescence of Lanthanides
  • Place of Presentation: オデッサ, ウクライナ
• [Presentation] pH-Controlled Anion Responsive Luminescence of Pyridine-Containing Cyclen-Eu^<3+> Complex (2010)
  • Author(s): S. Shinoda, Y. Yasueda, and H. Tsukube
  • Organizer: The 6th International Conference on Rare EarthDevelopment and Application
  • Place of Presentation: 北京,中国
• [Presentation] Dynamic Capping in Rotaxane Formation by Coordinate Bond (2010)
  • Author(s): T. Maeda, S. Shinoda, H. Miyake, and H. Tsukube
  • Organizer: 39th International Conference on Coordination Chemistry
  • Place of Presentation: アデレード,オーストラリア
• [Presentation] Combinatorial Optimization of Lanthanide Complexes as CD Probes for Amino Acids (2010)
  • Author(s): S. Shinoda, K. Yano, and H. Tsukube
  • Organizer: 22nd International Symposium on Chirality (ISCD-22, Chirality2010)
  • Place of Presentation: 札幌,日本
• [Presentation] CD Sensing of Dianions by Lanthanide-Platinum Multi-Nuclear Complex (2010)
  • Author(s): S. Shinoda, A. Mizote, M. Eiraku Masaki, M. Yoneda, H. Miyake, and H. Tsukube
  • Organizer: Joint Symposium of Post 5th International Symposium on Macrocyclic and Supramolecular Chemistry and the 6th Symposium on Host-Guest Chemistry
  • Place of Presentation: 大阪, 日本
• [Presentation] Dynamically Capped Rotaxanes by Coordination Bonds with Metal Complexes (2010)
  • Author(s): T. Maeda, S. Shinoda, H. Miyake, and H. Tsukube
  • Organizer: Joint Symposium of Post 5th International Symposium on Macrocyclic and Supramolecular Chemistry and the 6th Symposium on Host-Guest Chemistry
  • Place of Presentation: 大阪, 日本
• [Presentation] Anion-Enhanced Luminescence of Nona-Coordinated Cyclen-Eu3+Complex at Neutral pH (2010)
  • Author(s): S. Shinoda, Y. Yasueda, and H. Tsukube
  • Organizer: 5th International Symposium on Macrocyclic and Supramolecular Chemistry
  • Place of Presentation: 奈良,日本
• [Presentation] 希土類イオンの配位化学を活用した分子認識・センシング (2010)
  • Author(s): 篠田哲史
  • Organizer: 第27回希土類討論会
  • Place of Presentation: 北九州, 日本
• [Presentation] 希土類イオンの配位化学を活用した分子認識・センシング (2010)
  • Author(s): 篠田哲史
  • Organizer: 第27回希土類討論会
  • Place of Presentation: 北九州国際会議場、北九州市、福岡県(招待講演)
• [Presentation] Anion-Enhanced Luminescence of Nona-Coordinated Cyclen-EU^<3+>Complex at Neutral pH (2010)
  • Author(s): S.Shinoda, Y.Yasueda, H.Tsukube
  • Organizer: 5th International Symposium on Macrocyclic & Supramolecular Chemistry
  • Place of Presentation: 奈良県新公会堂、奈良市、奈良県
• [Presentation] CD Sensing of Dianions by Lanthanide-Platinum Multi-Nuclear Complex (2010)
  • Author(s): S.Shinoda, A.Mizote, M.E.Masaki M.Yoneda, H.Miyake, H.Tsukube
  • Organizer: Post 5th International Symposium on Macrocyclic & Supramolecular Chemistry
  • Place of Presentation: 大阪国際交流センター、大阪市、大阪府
• [Presentation] Combinatorial Optimization of Lanthanide Complexes as CD Probes for Amino Acids (2010)
  • Author(s): S.Shinoda, K.Yano, H.Tsukube
  • Organizer: 22nd International Symposium on Chirality
  • Place of Presentation: 札幌コンベンションセンター、札幌市、北海道
• [Presentation] pH-Controlled Anion Responsive Luminescence of Pyridine-Containing Cy en-Eu^<3+>Complex (2010)
  • Author(s): S.Shinoda, Y.Yasueda, H.Tsukube
  • Organizer: 6th International Conference on Rare Earth Development and Application
  • Place of Presentation: 北京国際会議場、北京、中国
• [Presentation] Near-Infrared Luminescence Sensing of Biological Substrates Based on Lanthanide Coordination Chemsitry (2010)
  • Author(s): S.Shinoda
  • Organizer: First International Conference on Luminescence of Lanthanides
  • Place of Presentation: オデッサエキシビションセンター、オデッサ、ウクライナ(招待講演)
• [Presentation] pHに応答した希土類錯体のキラリティー発現および発光増大 (2010)
  • Author(s): 篠田哲史, 御前仁美, 安枝裕貴, 築部浩
  • Organizer: 第60回錯体化学討論会
  • Place of Presentation: 大阪国際交流センター、大阪市、大阪府
• [Presentation] 希土類錯体の近赤外発光を利用したアミノ酸のセンシング (2010)
  • Author(s): 篠田哲史, 矢野径子, 築部浩
  • Organizer: 第26回近赤外フォーラム
  • Place of Presentation: 文部科学省研究交流センター、筑波市、茨城県
• [Presentation] サイクレン―希土類錯体とカルボン酸アニオン間の相互キラリティー転写
  • Author(s): 安枝裕貴,篠田哲史,三宅弘之, 築部 浩
  • Organizer: 第２９回希土類討論会
  • Place of Presentation: 北海道札幌市
• [Presentation] Chirality Transfer between a Lanthanide Complex and a Carboxylate Anion on Ternary Complexation
  • Author(s): S. Shinoda, Y. Yasueda, H. Miyake,H. Tsukube
  • Organizer: 8th International Conference on f-Elements
  • Place of Presentation: Udine, Italy
• [Presentation] Zn(II) Porphyrin-Appended Lanthanide Complex as a Dual Emissive Molecular Sensor
  • Author(s): S. Shinoda, S. Sakai
  • Organizer: International Symposium on Rare Earths 2012 in Okinawa for the 30th Anniversary of The Rare Earth Society of Japan
  • Place of Presentation: Okinawa, Japan
• [Presentation] 近赤外発光 pH 指示薬としてのイッテルビウム置換トランスフェリン およびラクトフェリン
  • Author(s): 篠田哲史
  • Organizer: 第２８回近赤外フォーラム
  • Place of Presentation: 沖縄県那覇市
  • Invited
• [Presentation] イッテルビウム錯体の光反応を利用したドーパミンの近赤外発光検出
  • Author(s): 篠田哲史、德田千晴
  • Organizer: 第２８回近赤外フォーラム
  • Place of Presentation: 沖縄県那覇市
• [Book] Encyclopedia in Metalloproteins (2013)
  • Author(s): Y. Kataoka, S. Shinoda, and H. Tsukube
  • Publisher: Springer
• [Book] Encyclopedia of Metalloproteins (2013)
  • Author(s): S. Shinoda, H. Tsukube
  • Total Pages: 1300
  • Publisher: Springer
• [Remarks]
  • URL: http://www.sci.osaka-cu.ac.jp/chem/func
• [Remarks]
  • URL: http://www.sci.osaka-cu.ac.jp/chem/FC
• [Remarks]
  • URL: http://www.sci.osaka-cu.ac.jp/chem/func/FC/Publication.html