| Budget Amount *help |
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
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| Research Abstract |
Recently, application of plant viruses to nanotechnology have attracted much attention due to their fascinating nanostructures with discrete nano-space. However, it remains difficult to rationally design artificial viral capsid. In this project, we found that a synthesized viral β-annulus peptide (24 residues) showed spontaneous self-assembly into hollow nanocapsules (synthetic viral capsid) with the size of 30-50 nm in water. Moreover, we have succeeded in synthesizing magnetite and encapsulating M13 phage DNA into the artificial capsids.
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