| Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
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| Research Abstract |
We construct well-designed neural networks by using either embryonic or induced pluripotent stem cells. Both topographic and biochemical cell growth cues are patterned to guide the growth and connation of derived axons and dendrites. In addition, aligned nanofibers-based topographic and microfluidic circuits as well as integrated microelectrode arrays are used for more active control and monitoring cellular network activities. If successful, the derived neuron chips can be useful as model system for advanced study of drug screening.
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