Budget Amount *help |
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2012: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2010: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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Research Abstract |
A method to determine subtype of influenza viruses by using surface plasmons localized in microscopic region on a flat metal surface was developed. In this method, refractive index variation arisen from interactions between viruses and their monoclonal antibodies was measured. Theoretical calculation revealed that measurement region had a size of ~180nm in radius, and could be occupied by ~7 viruses. The detection of influenza viruses with certain subtype was successfully demonstrated.
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