Realtime CARS imaging of cellular response by stimulation of laser ablation
| Project/Area Number |
22360027
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|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied optics/Quantum optical engineering
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| Research Institution | Osaka University |
|---|
Principal Investigator |
HASHIMOTO Mamoru 大阪大学, 大学院・基礎工学研究科, 准教授 (70237949)
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|---|
| Co-Investigator(Kenkyū-buntansha) |
FUKUSHIMA Shuichiro 大阪大学, 大学院・基礎工学研究科, 助教 (40362644)
NIIOKA Hirohiko 大阪大学, 大学院・基礎工学研究科, 助教 (70552074)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥19,760,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥4,560,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2010: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
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| Keywords | 応用光学 / 量子光工学 / 非線形光学 / ラマン分光 / 非線形ラマン / 結晶化 / レーザートラッピング / 光学顕微鏡 / 無染色イメージング / リアルタイム観測 / 分子イメージング / 非線形光学効果 / ラマン散乱分光 / 超短パルスレーザー / 生体医用光学 |
|---|
| Research Abstract |
We have developed a multifocus coherent anti-Stokes Raman scattering microscopy system combined with a laser-beam ablation system. The developed system visualizes sample response by laser stimulation without staining at vide-rate. The laser beam for ablation is controlled independently of observation. The developed system was applied to cellular response by membrane disruption and crystallizationmonitoring by photon pressure.
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Report
(4 results)
Research Products
(53 results)
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[Patent(Industrial Property Rights)] パルスレーザ光のタイミング調整装置,調整法及び光学顕微鏡2011
Inventor(s)
橋本守,南川丈夫,谷本尚生,小林実,藤田克昌,河田聡,荒木勉
Industrial Property Rights Holder
橋本守,南川丈夫,谷本尚生,小林実,藤田克昌,河田聡,荒木勉
Acquisition Date
2011-11-18
Related Report
