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Development of high-sensitivity and ultra-low volume infrared gasspectroscopy system for breath analysis

Research Project

Project/Area Number 22360135
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Electron device/Electronic equipment
Research InstitutionTohoku University

Principal Investigator

MATSUURA Yuji  東北大学, 大学院・医工学研究科, 教授 (10241530)

Co-Investigator(Kenkyū-buntansha) KATAGIRI Takashi  東北大学, 大学院・工学研究科, 准教授 (90415125)
KINO Saiko  東北大学, 大学院・医工学研究科, 教育研究支援者 (30536082)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2012: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2010: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Keywordsセンシング / 呼気分析 / 赤外分光法 / ラマン分光法 / 中空光ファイバ / ガス分光分析
Research Abstract

To detect minor components in breath, a spectroscopic measurement system using a quantum cascade laser and a hollow optical fiber was developed. By optimizing the optic system and signal processing method, quantitative measurement of ppm-order gas component was successfully demonstrated. Subsequently, to devlop a cavity-ring-down spectroscopy system having further high sensitivity, hollow optical waveguides with inner dielectric layers were fabricated. By forming multiple dielectric layers on the inside, the transmission losses are largely decreased compared to common hollow waveguides with a single dielectric layer.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (42 results)

All 2013 2012 2011 2010 Other

All Journal Article (11 results) (of which Peer Reviewed: 11 results) Presentation (29 results) Book (2 results)

  • [Journal Article] Design and optimization of hollow-optical-fiber gas cell for infrared spectroscopy Opt2013

    • Author(s)
      Y. Takahashi, S. Kino, Y. Matsuura
    • Journal Title

      Eng

      Volume: 52 Issue: 1 Pages: 1-5

    • DOI

      10.1117/1.oe.52.1.013601

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fabrication method of small-diameter hollow waveguides for terahertz waves2012

    • Author(s)
      S. Sato, T. Katagiri, Y. Matsuura
    • Journal Title

      J. Opt. Soc. Am

      Volume: B29 Issue: 11 Pages: 3006-3009

    • DOI

      10.1364/josab.29.003006

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Remote Fourier transform-infrared spectral imaging system with hollow-optical fiber bundle2012

    • Author(s)
      C. Huang, T. Katagiri, Y. Matsuura
    • Journal Title

      Appl. Opt

      Volume: 51 Issue: 29 Pages: 6913-6916

    • DOI

      10.1364/ao.51.006913

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 医療用光ファイバーの基礎2011

    • Author(s)
      松浦祐司
    • Journal Title

      日本レーザー医学会誌

      Volume: 31 Pages: 407-412

    • NAID

      10027810275

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 内視鏡下光診断のための中空光ファイバ応用システム2011

    • Author(s)
      松浦祐司
    • Journal Title

      レーザー研究

      Volume: 39 Pages: 118-122

    • NAID

      10027781811

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 医療用中空光ファイバとその応用システム2011

    • Author(s)
      松浦祐司
    • Journal Title

      応用物理

      Volume: 80 Pages: 1078-1081

    • NAID

      10030157981

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 中空光ファイバ減衰全反射プローブによる水中塩分濃度の赤外分光測定2011

    • Author(s)
      田中雄樹, 木野彩子, 松浦祐司
    • Journal Title

      レーザー研究

      Volume: 39 Pages: 938-941

    • NAID

      10030152083

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Flexible hollow optical fiber bundle for infrared thermal imaging, Biomed2010

    • Author(s)
      Y. Matsuura, K. Naito
    • Journal Title

      Opt. Express

      Volume: 2 Pages: 65-65

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 中空光ファイバの基礎2010

    • Author(s)
      松浦祐司
    • Journal Title

      Medical Photonics

      Volume: 1 Pages: 11-15

    • URL

      http://www.medicalphotonics.jp/pdf/mp0002/0002_011.pdf

    • Related Report
      2012 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 中空光ファイバの医療応用2010

    • Author(s)
      松浦祐司
    • Journal Title

      Medical Photonics

      Volume: 1 Pages: 16-21

    • URL

      http://www.medicalphotonics.jp/pdf/mp0002/0002_016.pdf?

    • Related Report
      2012 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Flexible hollow optical fiber bundle for infrared thermal imaging2010

    • Author(s)
      Y.Matsuura, K.Naito
    • Journal Title

      Biomed.Opt.Express

      Volume: 2 Pages: 65-70

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 中空光ファイバとその医療応用2013

    • Author(s)
      松浦祐司
    • Organizer
      光波シンセシス研究会
    • Place of Presentation
      仙台
    • Year and Date
      2013-02-28
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] Hollow waveguide with multiple dielectric layer for infrared cavity-ring-down spectroscopy2013

    • Author(s)
      R. Ichikawa, T. Katagiri, Y. Matsuura
    • Organizer
      SPIE Conference on Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIII
    • Place of Presentation
      San Francisco, USA.
    • Year and Date
      2013-02-02
    • Related Report
      2012 Final Research Report
  • [Presentation] 赤外キャビティリングダウン分光用多層薄膜クラッド中空導波路の製作2012

    • Author(s)
      市川遼,片桐崇史,松浦祐司
    • Organizer
      電子情報通信学会光エレクトロニクス研究会(OPE)
    • Place of Presentation
      東京
    • Year and Date
      2012-11-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 多層誘電薄膜を内装した赤外キャビティリングダウン分光用中空導波路2012

    • Author(s)
      市川遼,片桐崇史,松浦祐司
    • Organizer
      第548会伝送工学研究会
    • Place of Presentation
      仙台
    • Year and Date
      2012-10-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 多層誘電薄膜を内装した赤外キャビティリングダウン分光用中空導波路2012

    • Author(s)
      市川遼,片桐崇史,松浦祐司
    • Organizer
      電子情報通信学会ソサイエティ大会
    • Place of Presentation
      富山
    • Year and Date
      2012-09-13
    • Related Report
      2012 Final Research Report
  • [Presentation] 中空光ファイバガスセルを用いた紫外ガス吸収分光の研究2012

    • Author(s)
      出仙勇毅,松浦祐司
    • Organizer
      平成24年度電気関係学会東北支部連合大会
    • Place of Presentation
      秋田
    • Year and Date
      2012-08-30
    • Related Report
      2012 Final Research Report
  • [Presentation] 中空光ファイバの基礎と医療応用2012

    • Author(s)
      松浦祐司
    • Organizer
      2012年電子情報通信学会総合大会
    • Place of Presentation
      岡山
    • Year and Date
      2012-03-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 赤外キャビティリングダウン分光用超低損失中空導波路の製作2012

    • Author(s)
      市川遼
    • Organizer
      2012年電子情報通信学会総合大会
    • Place of Presentation
      岡山
    • Year and Date
      2012-03-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] 中空光ファイバガスセルを用いた呼気分析-量子カスケードレーザーを用いたNOガス測定-2012

    • Author(s)
      高橋侑右
    • Organizer
      レーザー学会学術講演会第32回年次大会
    • Place of Presentation
      仙台
    • Year and Date
      2012-02-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 呼気分析のための中空光ファイバ型長光路マイクロボリュームガスセル2011

    • Author(s)
      高橋侑右
    • Organizer
      電子情報通信学会2011年ソサイエティ大会
    • Place of Presentation
      札幌
    • Year and Date
      2011-09-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] 赤外キャビティリングダウン分光用中空光導波路ガスセルの製作2011

    • Author(s)
      市川遼
    • Organizer
      平成23年度電気関係学会東北支部連合大会
    • Place of Presentation
      仙台
    • Year and Date
      2011-08-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] Small-volume cavity cell using hollow optical fiber for Raman scattering-based gas detection2011

    • Author(s)
      Y. Okita, T. Katagiri, Y. Matsuura
    • Organizer
      SPIE Conference on Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2011-01-23
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] Matsuura, Hollow fiber-based Raman tweezers, SPIE Conference on Optical Fibers2011

    • Author(s)
      T. Katagiri, Y. Morisaki, Y.
    • Organizer
      Sensors, and Devices for Biomedical Diagnostics and Treatment XI
    • Place of Presentation
      San Francisco, USA.
    • Year and Date
      2011-01-23
    • Related Report
      2012 Final Research Report
  • [Presentation] Flexible hollow-fiber bundle for body temperature imaging, SPIE Conference on Optical Fibers2011

    • Author(s)
      Y. Matsuura, K. Naito
    • Organizer
      Sensors, and Devices for Biomedical Diagnostics and Treatment XI
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2011-01-23
    • Related Report
      2012 Final Research Report
  • [Presentation] Hollow fiber-based Raman tweezers2011

    • Author(s)
      T.Katagiri, Y.Morisaki, Y.Matsuura
    • Organizer
      SPIE Conference on Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2011-01-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Flexible hollow-fiber bundle for body temperature imaging2011

    • Author(s)
      Y.Matsuura, K.Naito
    • Organizer
      SPIE Conference on Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2011-01-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Fabrication of silver-coated hollow fiber with an inner diameter of 100 micron or less2011

    • Author(s)
      K.Iwai, M.Miyagi, Y.Shi, Y.Matsuura
    • Organizer
      SPIE Conference on Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2011-01-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] 呼気分光分析のための中空光ファイバガスセルの最適化2011

    • Author(s)
      高橋侑右,木野彩子,松浦祐司
    • Organizer
      レーザー学会学術講演会第31回年次大会
    • Place of Presentation
      東京
    • Year and Date
      2011-01-09
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] 中空光ファイバ型ガスセルを用いた赤外ガス分光分析2010

    • Author(s)
      高橋侑右,木野彩子,松浦祐司
    • Organizer
      第22回電気関係学会東北支部連合大会
    • Place of Presentation
      青森
    • Year and Date
      2010-08-27
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] ラマンイメージング用中空光ファイババンドルの試作2010

    • Author(s)
      冨山達弘, 片桐崇史, 松浦祐司
    • Organizer
      第22回電気関係学会東北支部連合大会
    • Place of Presentation
      青森
    • Year and Date
      2010-08-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 呼気のリアルタイムラマン分析のための高感度中空光ファイバ型ガスセル2010

    • Author(s)
      沖田佳也,片桐崇史,松浦祐司
    • Organizer
      第71回応用物理学会学術講演会
    • Place of Presentation
      長崎
    • Year and Date
      2010-08-16
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] Remote-Raman spectroscopy of optically trapped particles by utilizing a hollow optical fiber2010

    • Author(s)
      T. Katagiri, Y. Matsuura
    • Organizer
      SPIE Conference on Optical Trapping and Optical Micromanipulation VII
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2010-08-04
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] Endoscopic optical diagnosis and surgery system based on hollow optical fiber (Invited Paper)2010

    • Author(s)
      Y. Matsuura
    • Organizer
      OECC2010
    • Place of Presentation
      札幌
    • Year and Date
      2010-07-09
    • Related Report
      2012 Final Research Report
  • [Presentation] Endoscopic optical diagnosis and surgery system based on hollow optical fiber2010

    • Author(s)
      Y.Matsuura, T.Watanabe, S.Kino
    • Organizer
      OECC2010
    • Place of Presentation
      Sapporo(Invited Paper)(招待講演)
    • Year and Date
      2010-07-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Hollow waveguide with multiple dielectric layer for infrared cavity-ring-down spectroscopy

    • Author(s)
      R. Ichikawa
    • Organizer
      SPIE Conference on Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIII
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] 多層誘電薄膜を内装した赤外キャビティリングダウン分光用中空導波路

    • Author(s)
      市川遼
    • Organizer
      電子情報通信学会2013年ソサイエティ大会
    • Place of Presentation
      富山大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] 中空光ファイバガスセルを用いた紫外ガス吸収分光の研究

    • Author(s)
      出仙勇毅
    • Organizer
      平成24年度電気関係学会東北支部連合大会
    • Place of Presentation
      秋田県立大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] 赤外分光キャビティーガスセルのための多層薄膜内装中空導波路の製作

    • Author(s)
      市川遼
    • Organizer
      第548会伝送工学研究会
    • Place of Presentation
      東北大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] 赤外キャビティリングダウン分光用多層薄膜クラッド中空導波路の製作

    • Author(s)
      市川遼
    • Organizer
      電子情報通信学会光エレクトロニクス研究会(OPE)
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Book] Optical Guided-wave Chemical and Biosensors II2010

    • Author(s)
      M. Zourob, A. Lakhtakia, Y. Matsuura, et al
    • Publisher
      Springer
    • Related Report
      2012 Final Research Report
  • [Book] Optical Guided-wave Chemical and Biosensors II2010

    • Author(s)
      Y.Matsuura, et al
    • Publisher
      Springer
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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