| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2012: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2011: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2010: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Research Abstract |
We had found that avirulence factors possess the suppressor function in addition to the common eliciting function of cultivar-specific resistance responses. PthA, a canker-forming effector with homology to the avirulence effector (AvrBs3) group commonly found in xanthomonads, was found to possess the suppressor function too. Here we found that PthA can bind specifically to the precursor for pectin methyl esterase (PME) of Citrus led to the new strategy to create the canker-resistant Citrus by the introduction of the PME precursors of other plant sources together with the introduction of mutation into the citrus PME precursor or gene silencing of PME precursor gene of Citrus by RNA interference. We suggest this modification of the suppressor activities of avirulence effectors by modification of their binding protein in the host plants as a new strategy for the construction of disease-resistant plants.
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