| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Outline of Final Research Achievements |
Sinorhizobium meliloti is a root-nodule bacterium that establishes symbiosis with leguminous plants and performs nitrogen fixation. In this study, we analyzed the regulon of its sigma factor RpoH1, which is essential for heat shock response and effective symtiosis, and identified a member of the regulon, SMc00302 (designated later as sufT) to have an essential role in symbiosis. Functional analysis of this gene showed that SufT homologs are distributed widely over prokaryotes and eukaryotes and the rhizobial SufT operates to enhance the iron-sulfur cluster biogenesis in the cell under iron-limiting conditions.
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