| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2011: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
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| Research Abstract |
We worked on the research related with filamentous fungus Mortierella alpina which produces microbial oils rich in beneficial fatty acids such as arachidonic acid and eicosapentaenoic acid. First, we constructed a gene manipulation system of this fungus and enhanced the lipid productivities by metabolic engineering. This stain accumulates not only beneficial fatty acids but also unique sterols. Second, we evaluated enzyme genes involved in sterol biosynthetic pathways to improve sterol productivities by molecular breeding of this fungus.
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