Nematic ordered cellulose templates mediating 3 dimensional order-patterned deposition accompanied with synthesis of calcium phosphates
| Project/Area Number |
22380097
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Wood science
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| Research Institution | Kyushu University |
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Principal Investigator |
KONDO Tetsuo 九州大学, 大学院・農学研究院, 教授 (30202071)
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| Co-Investigator(Renkei-kenkyūsha) |
TATSUMI Daisuke 九州大学, 大学院・農学研究院, 准教授 (60293908)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2010: ¥14,430,000 (Direct Cost: ¥11,100,000、Indirect Cost: ¥3,330,000)
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| Keywords | セルロース / テンプレート / バイオファブリケーション / ホスト-ゲスト バイオミネラリゼーション / ヒドロキシアパタイト / ホスト-ゲスト バイオミネラリゼーション |
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| Research Abstract |
This study attempts to propose a sortof biomimic mineralization using the template. It combines morphologically controlling process with synthesis of the calcium phosphate as a major component of bones. This process was successfully mediated by the modified NOC template having a pair of roles of the ion supply sources and scaffolds for 3D-ordering architecture of the calcium phosphate as a biomineral in the key functions for biomineralization. Secondly, the ordered cellulosefilm scaffold, NOC, also induced establishment of a three-dimensional, hierarchical structure of epidermal cells by cell attachment and subsequent culture. Furthermore, the NOC film, as a semipermeable template, was also employed to allow three-dimensional proliferation of epidermal cell layers in the perpendicular direction. The template provedto be a suitable as a three-dimensional cell culture device, resulting in the proposal that the construction processes of these three-dimensional cell layers followed the basic concept of skin formation
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Report
(4 results)
Research Products
(40 results)
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[Journal Article] Regulated patterns of bacterial movements based on their secreted cellulose nanofibers interacting interfacially with ordered chitin templates2012
Author(s)
Kondo, T., Kasai, W., Nojiri, M., Hishikawa, Y., Togawa, E., Romanovicz, D. and R. Malcolm Brown, Jr.
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Journal Title
J. Biosci. Bioeng.
Volume: 114(1)
Pages: 113-120
NAID
Related Report
Peer Reviewed
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