Endocrine and metabolic studies on single nucleotide polymorphism of GH gene in Japanese Black cattle
| Project/Area Number |
22380143
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Tohoku University |
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Principal Investigator |
KATOH Kazuo 東北大学, 大学院・農学研究科, 教授 (60091831)
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| Co-Investigator(Kenkyū-buntansha) |
SANO Hiroaki 岩手大学, 農学部, 教授 (20196306)
ROH Sang-gun 東北大学, 大学院・農学研究科, 准教授 (90322130)
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| Co-Investigator(Renkei-kenkyūsha) |
HIRAYAMA Takuji 琉球大学, 農学部, 助教 (00274887)
HAGINO Akihiko 東北大学, 大学院・農学研究科, 助教 (80156249)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥19,760,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥4,560,000)
Fiscal Year 2012: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2010: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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| Keywords | 黒毛和種牛 / 遺伝子多型 / 成長ホルモン / 脂肪細胞 / インスリン / 不飽和脂肪酸 / GH分泌 / 脂肪酸合成 |
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| Research Abstract |
1) We successfully established an applied method of Dot-plot-SNP for analyzing GH single nucleotide polymorphisms (SNPs), 2) In the studies on gene expression of fatty acid synthesis enzymes (FASN, SCD and SREBP-1), adipocytes isolated from the animal with type CC demonstrated greater sensitivity to GH stimulation than those with another type, 3) Glucose-clamp analysis demonstrated greater insulin sensitivity in the animals with the type AA than that with type BB.
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Report
(4 results)
Research Products
(55 results)
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[Journal Article] Proliferating bovine intramuscular preadipocyte cell synthesize leptin2013
Author(s)
Yonekura, S., Tokutake, Y., Hirota, S., Rose, M. T., Katoh, K. and Aso, H
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Journal Title
Domestic Animal Endocrinology
Volume: (in press)
Related Report
Peer Reviewed
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[Journal Article] A high-protein diet induces dissociation between plasma concentrations of growth hormone and ghrelin in wethers2012
Author(s)
Takahashi, T., Kobayashi, Y., Haga, S., Ohtani, Y., Sato, K., Obara, Y., Hagino, A., Roh, S.G. and Katoh, K
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Journal Title
Journal of Animal Science
Volume: 90
Pages: 4807-13
Related Report
Peer Reviewed
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[Journal Article] Photoperiod regulates corticosterone rhythms byaltered adrenal sensitivity via melatonin-independent mechanisms in fischer 344 rats and C57BL/6J mice2012
Author(s)
Otsuka, T., Goto, M., Kawai, M., Togo, Y., Sato, K., Katoh, K., Mitsuhiro Furuse, M., Yasuo, S
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Journal Title
PLOS ONE
Volume: 7
Issue: 6
Pages: e39090-e39090
DOI
Related Report
Peer Reviewed
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[Journal Article] The regulation of chemerin and CMKLR1 genes expression by TNF-α,adiponectin and chemerin analog in bovine differentiated adipocytes2012
Author(s)
Suzuki, Y., Song, S.H., Ardiyanti, A., Kato, T., So, K.H., Katoh, K. and Roh, S.G.
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Journal Title
AJAS
Volume: 25
Issue: 9
Pages: 1316-1321
DOI
Related Report
Peer Reviewed
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[Journal Article] Contributions of FASN and SCD gene polymorphisms on fatty acid composition in muscle from Japanese Black cattle2012
Author(s)
Yokota, S., Sugita, H., Ardiyanti, A., Shoji, N., Nakajima, H., Otomo, Y., Suda, Y., Katoh, K. and Suzuki, K
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Journal Title
Animal Genetics
Volume: 43
Issue: 6
Pages: 431-433
DOI
Related Report
Peer Reviewed
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[Journal Article] Effects at early stage of life of elevated milk replacer feeding on growth rate, plasma IGF-I concentration and intestinal nutrient transporter expression in Holstein bull calves2012
Author(s)
Orihashi, T., Mashiko, T., Sera, K., Roh, S.-G., Katoh, K., and Obara, Y
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Journal Title
Animal Science Journal
Volume: 83
Issue: 1
Pages: 77-82
DOI
Related Report
Peer Reviewed
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[Journal Article] Effects of sodium-butyrate -supplementation in milk formula on plasma concentrations of GH and insulin, and on rumen papilla development in calves2011
Author(s)
Kato, S., Sato, K., Chida, H., Roh, S.-G., Ohwada, S., Sato, S., Guilloteau, P. and Katoh, K
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Journal Title
Journal of Endocrinology
Volume: 211
Issue: 3
Pages: 241-248
DOI
Related Report
Peer Reviewed
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