Studies on the susceptibility of terrestrial wild bird and the propagation to highly pathogenic avian influenza virus

• Project/Area Number: 22380167
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Applied veterinary science
• Research Institution: Tottori University
• Principal Investigator: ITO Toshihiro 鳥取大学, 農学部, 教授 (00176348)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000); Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2011: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000); Fiscal Year 2010: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
• Keywords: 人獣共通感染症 / 獣医学 / 微生物 / ウイルス / 鳥インフルエンザ / 陸生野鳥 / インフルエンザウイルス / 感受性 / 伝播 / 病原性 / 感覚性

Research Abstract

In this study, the infection experiment supposing various infection routes of highly pathogenic avian influenza virus in field was conducted.
The results obtained showed that (1) the virus spreads from infected wild waterfowl to terrestrial wild bird through the water of lake
(2) the infected terrestrial wild bird invades in a henhouse, and a virus spreads by contacting with a chicken
but (3) between terrestrial wild birds, it is hard to consider a possibility that infection will spread one after another.
These results support the notion that the invasion preventive measures of the terrestrial wild bird into a henhouse are very important on the epidemic prevention of highly pathogenic avian influenza avian influenza.

Research Products

• [Journal Article] Incursion and Spread of H5N1 Highly Pathogenic Avian Influenza Virusesamong Wild Birds in 2010- 11 Winter in Japan. (2013)
  • Author(s): Soda, K., Ito, H., Usui, T., Nagai, Y., Ozaki, H., Yamaguchi, T., and Ito, T
• [Journal Article] Pathogenicity of an H5N1 Highly Pathogenic Avian Influenza Virus Isolated in the 2010-2011 Winter in Japan to Mandarin Ducks (2013)
  • Author(s): oda, K., Usui, T., Uno, Y., Yoneda, K., Yamaguchi, T., and Ito, T.
  • Journal Title: J. Vet. Med. Sci Volume: 75
  • NAID: 130003362108
• [Journal Article] The Pathogenicity and Host Immune Response Associated with H5N1 Highly Pathogenic Avian Influenza Virus in Quail (2013)
  • Author(s): Uno, Y., Usui, T., Soda, K., Fujimoto, Y., Takeuchi, T., Ito, H., Ito, T., and Yamaguchi, T.
  • Journal Title: J. Vet. Med. Sci. Volume: 75 Pages: 451-457
  • NAID: 130002502192
• [Journal Article] The Pathogenicity and Host Immune Response Associated with H5N1 Highly Pathogenic Avian Influenza Virus in Quail (2013)
  • Author(s): Uno, Y.
  • Journal Title: Journal of Veterinary Medical Science Volume: 75 Issue: 4 Pages: 451-457
  • DOI: 10.1292/jvms.12-0433
  • NAID: 130002502192
  • ISSN: 0916-7250, 1347-7439
  • Peer Reviewed
• [Journal Article] Pathogenicity of an H5N1 Highly Pathogenic Avian Influenza Virus Isolated in the 2010–2011 Winter in Japan to Mandarin Ducks (2013)
  • Author(s): Soda, K.
  • Journal Title: Journal of Veterinary Medical Science Volume: 75 Issue: 5 Pages: 619-624
  • DOI: 10.1292/jvms.12-0487
  • NAID: 130003362108
  • ISSN: 0916-7250, 1347-7439
  • Peer Reviewed
• [Journal Article] Incursion and Spread of H5N1 Highly Pathogenic Avian Influenza Viruses among Wild Birds in 2010–11 Winter in Japan (2013)
  • Author(s): Soda, K.
  • Journal Title: Journal of Veterinary Medical Science Volume: 75 Issue: 5 Pages: 605-612
  • DOI: 10.1292/jvms.12-0512
  • NAID: 130003362109
  • ISSN: 0916-7250, 1347-7439
  • Peer Reviewed
• [Journal Article] Isolation and characterization of H6N1 and H9N2 avian influenza viruses from Ducks in Hanoi (2012)
  • Author(s): Hotta K, Takakuwa H, Le QM, Phuong SL, Murase T, Ono E, Ito T, Otsuki K, Yamashiro T
  • Journal Title: Vietnam. Virus Res Volume: 163 Pages: 448-453
• [Journal Article] Reintroduction of H5N1 highly pathogenic avian influenza virus by migratory water birds.causing poultry outbreaks in 2010-2011 winter season in Japan. (2012)
  • Author(s): Sakoda Y, Ito H, Uchida Y, Okamatsu M, Yamamoto N, Soda K, Nomura N, Kuribayashi S, Shichinohe S, Sunden Y, Umemura T, Usui T, Ozaki H, Yamaguchi T, Murase T, Ito T, Saito T, Takada A, Kida H.
  • Journal Title: J. Gen. Virol. Volume: 93 Pages: 541-550
• [Journal Article] Adaptation of a duck influenza A virus in quail (2012)
  • Author(s): Yamada S, Shinya K, Takada A, Ito T, Suzuki T, Suzuki Y, Le QM, Ebina M, Kasai N, Kida H, Horimoto T, Rivailler P, Chen LM, Donis RO, Kawaoka Y
  • Journal Title: J.Virol. Volume: 86 Pages: 1411-1420
• [Journal Article] Reintroduction of H5N1 highly pathogenic avian influenza virus by migratory water birds, causing poultry outbreaks in 2010-2011 winter season in Japan (2012)
  • Author(s): Sakoda, Y.
  • Journal Title: J.Gen.Virol. Volume: 93(3) Issue: 3 Pages: 541-550
  • DOI: 10.1099/vir.0.037572-0
  • Peer Reviewed
• [Journal Article] Isolation and characterization of H6N1 and H9N2 avian influenza viruses from Ducks in Hanoi, Vietnam (2012)
  • Author(s): Hotta, K.
  • Journal Title: Virus Res. Volume: 163(2) Issue: 2 Pages: 448-453
  • DOI: 10.1016/j.virusres.2011.11.004
  • Peer Reviewed
• [Journal Article] Highly pathogenic avian influenza virus infection in feral raccoons, Japan (2011)
  • Author(s): Horimoto T, Maeda K, Murakami S, Kiso M, Iwatsuki-Horimoto K, Sashika M, Ito T,Suzuki K, Yokoyama M, Kawaoka Y.
  • Journal Title: Emerg.Infectious Dis Volume: 17 Pages: 714-717
• [Journal Article] Highly pathogenic avian influenza virus infection in feral raccoons, Japan (2011)
  • Author(s): Horimoto T, Maeda K, Murakami S, Kiso M, Iwatsuki-Horimoto K, Sashika M, Ito T, Suzuki K, Yokoyama M, and Kawaoka Y
  • Journal Title: Emerg Infect Dis Volume: 17 Issue: 4 Pages: 714-717
  • DOI: 10.3201/eid1704.101604
  • Peer Reviewed
• [Journal Article] Adaptation of a duck influenza A virus in quail (2011)
  • Author(s): Yamada S, Shinya K, Takada A, Ito T, Suzuki T, Suzuki Y, Le QM, Ebina M, Kasai N, Kida H, Horimoto T, Rivailler P, Chen LM, Donis RO, Kawaoka Y
  • Journal Title: J Virol Volume: 86(3) Issue: 3 Pages: 1411-1420
  • DOI: 10.1128/jvi.06100-11
  • Peer Reviewed
• [Journal Article] Avian Influenza Virus and Paramyxovirus Isolation from Migratory Waterfowl and Shorebirds in San-In District of Western Japan from 2001 to 2008 (2010)
  • Author(s): Fujimoto Y, Ito H, Shivakoti S, Nakamori J, Tsunekuni R, Otsuki K, Ito T
  • Journal Title: J. Vet. Med. Sci. Volume: 72 Pages: 963-967
  • NAID: 130000264272
• [Journal Article] Characterization of H5N1 Highly Pathogenic Avian Influenza Virus Isolated from a Mountain Hawk Eagle in Japan (2010)
  • Author(s): Shivakoti, S.,Ito, H., Otsuki, K., and Ito, T.
  • Journal Title: J. Vet. Med. Sci Volume: 72 Pages: 459-463
  • NAID: 130000149949
• [Journal Article] Susceptibility of two species of wild terrestrial birds to infection with a highly pathogenic avian influenza virus of H5N1 subtype (2010)
  • Author(s): Fujimoto, Y., Ito, H., Shinya, K., Yamaguchi, T., Usui, T., Murase,T., Ozaki, H., Ono, E., Takakuwa, H., Otsuki, K., and Ito, T.
  • Journal Title: Avian Pathology Volume: 39 Pages: 95-98
• [Journal Article] Susceptibility of two species of wild terrestrial birds to infection with a highly pathogenic avian influenza virus of H5N1 subtype. (2010)
  • Author(s): Fujimoto, Y.
  • Journal Title: Avian Pathology Volume: 39 Pages: 95-98
  • Peer Reviewed
• [Journal Article] Characterization of H5N1 Highly Pathogenic Avian Influenza Virus Isolated from a Mountain Hawk Eagle in Japan. (2010)
  • Author(s): Shivakoti, S.
  • Journal Title: J.Vet.Med.Sci. Volume: 72 Pages: 459-463
  • Peer Reviewed
• [Journal Article] Avian Influenza Virus and Paramyxovirus Isolation from Migratory Water fowl and Shorebirds in San-In District of Western Japan from 2001 to 2008. (2010)
  • Author(s): Fujimoto, Y.
  • Journal Title: J.Vet.Med.Sci. Volume: 72 Pages: 963-967
  • Peer Reviewed
• [Presentation] 高病原性鳥インフルエンザの国内発生と野鳥との関わり (2012)
  • Author(s): 伊藤壽啓
  • Organizer: 鳥インフルエンザ公開シンポジウム
  • Place of Presentation: 宮崎市.
  • Year and Date: 2012-10-27
• [Presentation] 高病原性鳥インフルエンザ流行 (2012)
  • Author(s): 伊藤壽啓
  • Organizer: 第153回日本獣医学会学術集会微生物分科会シンポジウム.
  • Place of Presentation: 大宮市.
  • Year and Date: 2012-03-28
• [Presentation] 高病原性鳥インフルエンザ流行 (2012)
  • Author(s): 伊藤壽啓
  • Organizer: 第153回日本獣医学会学術集会微生物分科会シンポジウム
  • Place of Presentation: 大宮ソニックシティ(埼玉県)
  • Year and Date: 2012-03-28
• [Presentation] 日本での鳥インフルエンザの現状 (2012)
  • Author(s): 伊藤壽啓
  • Organizer: 平成23年度日本獣医師会獣医学術文学会年次大会文部科学省科研費市民公開シンポジウム
  • Place of Presentation: 札幌市
  • Year and Date: 2012-02-05
• [Presentation] 日本での鳥インフルエンザの現状 (2012)
  • Author(s): 伊藤壽啓
  • Organizer: 平成23年度日本獣医師会獣医学術文学会年次大会文部科学省科研費市民公開シンポジウム
  • Place of Presentation: 札幌コンベンションセンター(北海道)
  • Year and Date: 2012-02-05
• [Presentation] 野鳥における高病原性鳥インフルエンザウイルス疫学調査について (2011)
  • Author(s): 伊藤壽啓
  • Organizer: 第151回日本獣医学会学術集会特別企画日本野生動物医学会シンポジウム
  • Place of Presentation: 大阪市.
  • Year and Date: 2011-09-20
• [Presentation] 野鳥における高病原性鳥インフルエンザウイルス疫学調査について (2011)
  • Author(s): 伊藤壽啓
  • Organizer: 第151回日本獣医学会学術集会特別企画日本野生動物医学会シンポジウム
  • Place of Presentation: 大阪府立大学(大阪府)
  • Year and Date: 2011-09-20
• [Presentation] 鳥インフルエンザの疫学と対策 (2010)
  • Author(s): 伊藤壽啓
  • Organizer: 平成22年度全国鶏病技術研修会
  • Place of Presentation: 出雲市
  • Year and Date: 2010-10-15
• [Presentation] 鳥インフルエンザの疫学と対策 (2010)
  • Author(s): 伊藤壽啓
  • Organizer: 平成22年度全国鶏病技術研修会
  • Place of Presentation: 島根県出雲市
  • Year and Date: 2010-10-15
• [Presentation] 高病原性鳥インフルエンザの国内発生と野鳥との関わり
  • Author(s): 伊藤壽啓
  • Organizer: 鳥インフルエンザシンポジウム
  • Place of Presentation: 宮崎大学（宮崎県）
  • Invited