| Project/Area Number |
22380169
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Clinical veterinary science
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| Research Institution | Rakuno Gakuen University (2012-2013)
Hokkaido University (2010-2011) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
門平 睦代 帯広畜産大学, 畜産学部, 教授 (20313976)
今内 覚 北海道大学, 大学院・獣医学研究科, 准教授 (40396304)
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| Co-Investigator(Renkei-kenkyūsha) |
KADOHIRA Mutsuyo 帯広畜産大学, 畜産学部, 教授 (20313976)
KONNAI Satoshi 北海道大学, 大学院・獣医学研究科, 准教授 (40396304)
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| Project Period (FY) |
2010-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2013: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2010: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
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| Keywords | 牛ウイルス性下痢ウイルス / BVDV / 持続感染牛 / PI / 胎子感染 / サイトカイン / プロファイル / 防疫対策 / 持続感染 / 公共牧場 / CXCR-4 / サイトカインプロファイル |
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| Research Abstract |
In order to estimate the spread manner of bovine viral diarrhea virus (BVDV) in and among the dairy herd, epidemiological and immunological analyzes were done for the BVDV detected and free herd discriminated by the bulk tank milk tests. Although the correlation between the geographical place of farm and outbreak of BVDV was recognized, prevalent viruses were not common based on the genetical analysis of the detected virus gene. On the immunological analyzes, BVDV might prefer to localize in ovary fluid in the infected cattle. Moreover, it was strongly suspected that BVDV might bias the immune status of infected cattle for the easy transmission of virus in uterus.
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