• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Molecular mechanism of infection/inflammation-associatedcarcinogenesis and cancer prevention

Research Project

Project/Area Number 22390121
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Hygiene
Research InstitutionMie University

Principal Investigator

MURATA Mariko  三重大学, 大学院・医学系研究科, 教授 (10171141)

Co-Investigator(Kenkyū-buntansha) OIKAWA Shinji  三重大学, 大学院・医学系研究科, 准教授 (10277006)
HIRAKU Yusuke  三重大学, 大学院・医学系研究科, 講師 (30324510)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
Fiscal Year 2012: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2011: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2010: ¥9,490,000 (Direct Cost: ¥7,300,000、Indirect Cost: ¥2,190,000)
Keywords炎症 / 発がん / 活性酸素・窒素 / 8-ニトログアニン / 幹細胞 / 感染症 / 慢性炎症 / 発がん機構 / DNA損傷 / 活性酸素 / カーボンナノチューブ / エンドサイトーシス / 代謝酵素 / エピゲノム異常
Research Abstract

Chronic inflammation induced by biological, chemical, and physical factors has been found to be associated with the increased risk of cancer. We revealed that the nuclear localization of COX-2, which was reported to function as a transcription factor, was significantly associated with the up-regulation of stem cell marker in cancer tissues with parasite infection. COX-2 activation may be involved in stem cell proliferation/differentiation in inflammation-mediated carcinogenesis. 8-Nitroguanine was formed in stem cell marker-positive cells in inflammation-associated cancer tissues. Inflammation may increase the number of mutant stem cells, in which iNOS-dependent DNA damage occurs via NF-κB activation, leading to tumor development.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (123 results)

All 2013 2012 2011 2010 Other

All Journal Article (46 results) (of which Peer Reviewed: 46 results) Presentation (71 results) Book (5 results) Remarks (1 results)

  • [Journal Article] Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma2012

    • Author(s)
      Mo Y, Midorikawa K, Zhang Z, Zhou X, Ma N, Huang G, Hiraku Y, Oikawa S, Murata M
    • Journal Title

      Cancer Lett

      Volume: 323(2) Pages: 147-54

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis2012

    • Author(s)
      Murata M, Thanan R, Ma N, Kawanishi S
    • Journal Title

      J Biomed Biotechnol

      Volume: 2012 Pages: 623019-623019

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Proton pump inhibitors suppress iNOS-dependent DNA damage in Barrett's esophagus by increasing Mn-SOD expression.2012

    • Author(s)
      Thanan R, Ma N, Iijima K, Abe Y, Koike T,Shimosegawa T, Pinlaor S,Hiraku Y, Oikawa S, Murata M, Kawanishi S
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 421(2) Pages: 280-5

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inflammation-induced protein carbonylation contributes to poor prognosis of cholangiocarcinoma.2012

    • Author(s)
      Thanan R, Oikawa S, Yongvanit P, Hiraku Y, Ma N, Pinlaor S, Pairojkul C, Wongkham C, Sripa B, Khuntikeo N, Kawanishi S, Murata M
    • Journal Title

      Free Radic. Biol. Med

      Volume: 52(8) Pages: 1465-72

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nuclear localization of COX-2 in relation to the expression of stemness markers in urinary bladder cancer.2012

    • Author(s)
      Thanan R, Murata M, Ma N, Hiraku Y, Oikawa S, Hammam O, Wishahi M, El Leithy T, Kawanishi S
    • Journal Title

      Mediat. Inflamm

      Volume: 2012 Pages: 165879-165879

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Proton pump inhibitors suppress iNOS-dependent DNA damage in Barrett's esophagus by increasing Mn-SOD expression2012

    • Author(s)
      Thanan R, Ma N, Iijima K, Abe Y, Koike T, Shimosegawa T, Pinlaor S, Hiraku Y, Oikawa S, Murata M, Kawanishi S
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 421 Pages: 280-285

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure2012

    • Author(s)
      Huang S, Guo S, Guo F, Yang Q, Xiao X, Murata M, Ohnishi S, Kawanishi S, Ma N
    • Journal Title

      Eur. J . Histochem

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nitrative DNA damage induced by multi-walled carbon nanotube via endocytosis in human lung epithelial cells2012

    • Author(s)
      Guo F, Ma N, Horibe Y, Kawanishi S, Murata M, Hiraku Y
    • Journal Title

      Toxicol. Appl. Pharmacol

      Volume: 260(2) Pages: 183-92

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inflammation-induced protein carbonylation contributes to poor prognosis of cholangiocarcinoma2012

    • Author(s)
      Thanan, R.
    • Journal Title

      Free Radic.Biol.Med.

      Volume: (印刷中) Issue: 8 Pages: 1465-1472

    • DOI

      10.1016/j.freeradbiomed.2012.01.018

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nuclear Localization of COX-2 in relation to the Expression of Stemness Markers in Urinary Bladder Cancer2012

    • Author(s)
      Thanan R, Murata M, Ma N, Hammam O, Wishahi M, El Leithy T, Hiraku Y, Oikawa S, Kawanishi S
    • Journal Title

      Mediators Inflamm

      Volume: 2012 Pages: 165879-165879

    • DOI

      10.1155/2012/165879

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Proton pump inhibitors suppress iNOS-dependent DNA damage in Barrett's esophagus by increasing Mn-SOD expression.2012

    • Author(s)
      Thanan R
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 421 Issue: 2 Pages: 280-285

    • DOI

      10.1016/j.bbrc.2012.03.152

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nitrative DNA damage induced by multi-walled carbon nanotube via endocytosis in human lung epithelial cells2012

    • Author(s)
      Guo, F.
    • Journal Title

      Toxicol.Appl.Pharmacol.

      Volume: (印刷中) Issue: 2 Pages: 183-192

    • DOI

      10.1016/j.taap.2012.02.010

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma.2012

    • Author(s)
      Mo Y
    • Journal Title

      Cancer Lett

      Volume: 323 Issue: 2 Pages: 147-154

    • DOI

      10.1016/j.canlet.2012.03.042

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nitrative DNA damage induced by multi-walled carbon nanotube via endocytosis in human lung epithelial cells2012

    • Author(s)
      Guo, F., Ma, N., Horibe, Y., Kawanishi, S., Murata, M., Hiraku, Y.
    • Journal Title

      Toxicol.Appl.Pharmacol.

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inflammation-induced protein carbonylation contributes to poor prognosis of cholangiocarcinoma2012

    • Author(s)
      Thanan, R., Oikawa, S., Yongvanit, P., Hiraku, Y., Ma, N., Pinlaor, S., Pairojkul, C., Wongkham, C., Sripa, B., Khuntikeo, N., Kawanishi, S., Murata, M.
    • Journal Title

      Free Radic.Biol.Med.

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nuclear localization of COX-2 in relation to the expression of stemness markers in urinary bladder cancer2012

    • Author(s)
      Thanan, R., Murata, M., Ma, N., Hiraku, Y., Oikawa, S., Hammam, O., Wishahi, M., El Leithy, T., Kawanishi, S.
    • Journal Title

      Mediat.Inflamm.

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis (review)2012

    • Author(s)
      Murata M., Thanan R., Ma N., Kawanishi S.
    • Journal Title

      J.Biomed.Biotechnol.

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 8-Nitroguanine : A potential biomarker to evaluate the risk of inflammation-related carcinogenesis2012

    • Author(s)
      Ma, N., Murata, M., Ohnishi, S., Thanan, R., Hiraku, Y., Kawanishi, S.
    • Journal Title

      Biomarker

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanisms of oxidative DNA damage induced by carcinogenic arylamines.2011

    • Author(s)
      Murata M、Kawanishi S
    • Journal Title

      Front Biosci

      Volume: 1(16) Pages: 1132-43

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nitrative and oxidative DNA damage caused by K-ras mutation in mice2011

    • Author(s)
      Ohnishi S, Saito H, Suzuki N, Ma N, Hiraku Y, Murata M, Kawanishi, S
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 413 Pages: 236-240

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nitrative and oxidative DNA damage as potential survival biomarkers for nasopharyngeal carcinoma.2011

    • Author(s)
      Huang Y-J, Zhang B-B, Ma N, Murata M、Tang A-Z, Huang G-W
    • Journal Title

      Med Oncol

      Volume: 28 Pages: 377-84

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nitrative DNA damage and Oct3/4 expression in urinary bladder cancer with Schistosomahaematobium infection2011

    • Author(s)
      Ma N, Thanan, R, Kobayashi H, Hammam O, Wishahi M, Leithy TE,Hiraku Y、Amro el K, Oikawa S, Ohnishi S, Murata M、Kawanishi S
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 414 Pages: 344-349

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Astrocytic neuroprotection through induction of cytoprotective molecules; a proteomic analysis of mutant P301S tau-transgenic mouse2011

    • Author(s)
      Yata K, Oikawa S, Sasaki R, Shindo A, Yang R, Murata M, Kanamaru K, Tomimoto H
    • Journal Title

      Brain Res

      Volume: 1410 Pages: 12-23

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Proteomic identification of hippocampal proteins vulnerable to oxidative stress in excitotoxin-induced acute neuronal injury2011

    • Author(s)
      Furukawa A, Kawamoto Y, Chiba Y, Takei S, Hasegawa-Ishii S, Kawamura N, Yoshikawa K, Hosokawa M, Oikawa S, Kato M, Shimada A
    • Journal Title

      Neurobiol Dis

      Volume: 43 Pages: 706-714

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nitrative and oxidative DNA damage caused by K-ras mutation in mice2011

    • Author(s)
      Ohnishi, S.
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 413 Issue: 2 Pages: 236-240

    • DOI

      10.1016/j.bbrc.2011.08.076

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nitrative DNA damage and Oct3/4 expression in urinary bladder cancer with Schistosoma haematobium infection2011

    • Author(s)
      Ma N, et al
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 414 Issue: 2 Pages: 44-349

    • DOI

      10.1016/j.bbrc.2011.09.073

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanisms of oxidative DNA damage induced by carcinogenic arylamines2011

    • Author(s)
      Murata M, Kawanishi S
    • Journal Title

      Front Biosci

      Volume: 16 Issue: 1 Pages: 1132-43

    • DOI

      10.2741/3739

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nitrative and oxidative DNA damage as potential survival biomarkers for nasopharyngeal carcinoma2011

    • Author(s)
      Huang Y-J., Zhang B-B., Ma N., Murata M., Tang A-z., Huang G-W.
    • Journal Title

      Med.Oncol.

      Volume: 28 Pages: 377-84

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanisms of oxidative DNA damage induced by carcinogenic arylamines.2011

    • Author(s)
      Murata M, Kawanishi S.
    • Journal Title

      Front.Biosci.

      Volume: 16 Pages: 1132-1143

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduction of periductal fibrosis in liver fluke-infected hamsters after long-term curcumin treatment2010

    • Author(s)
      Pinlaor S, Prakobwong S, Hiraku Y, Pinlaor P, Laothong U, Yongvanit P
    • Journal Title

      Eur. J. Pharmacol

      Volume: 638 Pages: 134-141

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Protective effect of melatonin against Opisthorchis viverrini-induced oxidative and nitrosative DNA damage and liver injury in hamsters2010

    • Author(s)
      Laothong U, Pinlaor P, Hiraku Y, Boonsiri P, Prakobwong S, Khoontawad J, Pinlaor S
    • Journal Title

      J. Pineal Res

      Volume: 49 Pages: 271-282

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] DNA damage and estrogenic activity induced by the environmental pollutant 2-nitrotoluene and its metabolite2010

    • Author(s)
      Watanebe C, Egami T, Midorikawa K, Hiraku Y, Oikawa S, Kawanishi S, Murata M
    • Journal Title

      Environmental Health and Preventive Medicine

      Volume: 15 Pages: 319-326

    • NAID

      10029519330

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Role of Peroxisome Proliferator-activated Receptor-alpha in Hepatobiliary Injury Induced by Ammonium Perfluorooctanoate in Mouse Liver2010

    • Author(s)
      Minata M, Harada KH, Karrman A, Hitomi T, Hirosawa M, Murata M、Gonzalez FJ, Koizumi A
    • Journal Title

      Ind Health

      Volume: 48(1) Pages: 96-107

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Proteomic analysis of aging brain in SAMP10 mouse: a model of age-related cerebral degeneration2010

    • Author(s)
      Furukawa A, Oikawa S, Hasegawa-Ishii S, Chiba Y, Kawamura N, Takei S, Yoshikawa K, Hosokawa M, Kawanishi S, Shimada A
    • Journal Title

      Mech Ageing Dev

      Volume: 131(6) Pages: 379-88

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma2010

    • Author(s)
      Wang S, Xiao X, Zhou X, Huang T, Du C, Yu N, Mo Y, Lin L, Zhang J, Ma N, Murata M, Huang G, Zhang Z
    • Journal Title

      BMC Cancer

      Volume: 9;10 Pages: 617-617

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preferential induction of apoptosis in regulatory T cells by tributyltin: possible involvement in the exacerbation of allergic diseases2010

    • Author(s)
      Tada-Oikawa S, Murata M, Kato T
    • Journal Title

      Nippon Eiseigaku Zasshi

      Volume: 65(4) Pages: 530-5

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oxidatively generated DNA damage induced by 3-amino-5-mercapto-1,2,4-triazole, a metabolite of carcinogenic amitrole.2010

    • Author(s)
      Furukawa A, 査読有Oikawa S, Harada K, Sugiyama H, Hiraku Y, Murata M, Shimada A, Kawanishi S
    • Journal Title

      Mutat Res.

      Volume: 694(1-2) Pages: 7-12

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] High incidence of tumors in diabetic thrombin activatable fibrinolysis inhibitor and apolipoprotein E double deficient mice2010

    • Author(s)
      Beppu T, Gil-Bernabe P, Boveda-Ruiz D, D'Alessandro-Gabazza C, Matsuda Y, Toda M, Miyake Y, Shiraki K,Murata M、Murata T, Yano Y, Morser J, Gabazza EC, Takei Y.
    • Journal Title

      J Thromb Haemost.

      Volume: 8(11) Pages: 2514-22

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Romidepsin (FK228), a potent histone deacetylase inhibitor, induces apoptosis through the generation of hydrogen peroxide.2010

    • Author(s)
      Mizutani H,Hiraku Y,Tada-Oikawa S, Murata M, Ikemura K, Iwamoto T, Kagawa Y, Okuda M, Kawanishi S.
    • Journal Title

      Cancer Sci

      Volume: 101(10) Pages: 2214-9

    • NAID

      10027832563

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Proteomic identification of peroxiredoxin 6 for host defense against Opisthorchis viverriniinfection2010

    • Author(s)
      Khoontawad J, Wongkham C, Hiraku Y,Yo ngvanit P, Prakobwong S, Boonmars T, Pinlaor P, Pinlaor S
    • Journal Title

      Parasite Immunol

      Volume: 32 Pages: 314-323

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The role of iNOS-mediated DNA damage in infection- and asbestos-induced carcinogenesis2010

    • Author(s)
      Hiraku Y, Kawanishi S, Ichinose T, Murata M.
    • Journal Title

      Ann. NY Acad. Sci

      Volume: 1203 Pages: 15-22

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] DNA damage and estrogenic activity induced by the environmental pollutant 2-nitrotoluene and its metabolite.2010

    • Author(s)
      Watanabe C, Egami T, Midorikawa K, Hiraku Y, Oikawa S, Kawanishi S, Murata M.
    • Journal Title

      Environ.Health Prev.Med.

      Volume: 15 Pages: 319-326

    • NAID

      10029519330

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] トリブチルスズによる制御性T細胞のアポトーシス誘導-アレルギー疾患増悪への関与-2010

    • Author(s)
      及川(多田)佐枝子、村田真理子、加藤琢磨
    • Journal Title

      日本衛生学雑誌

      Volume: 65 Pages: 530-535

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oxidatively generated DNA damage induced by 3-amino-5-mercapto-1,2,4-triazole, a metabolite of carcinogenic amitrole.2010

    • Author(s)
      Furukawa A, Oikawa S, Harada K, Sugiyama H, Hiraku Y, Murata M, Shimada A, Kawanishi S.
    • Journal Title

      Mutat.Res.

      Volume: 694 Pages: 7-12

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High incidence of tumors in diabetic thrombin activatable fibrinolysis inhibitor and apolipoprotein E double deficient mice.2010

    • Author(s)
      Beppu T, Gil-Bernabe P, Boveda-Ruiz D, D'Alessandro-Gabazza C, Matsuda Y, Toda M, Miyake Y, Shiraki K, Murata M, Murata T, Yano Y, Morser J, Gabazza EC, Takei Y.
    • Journal Title

      J.Thromb.Haemost.

      Volume: 8 Pages: 2514-2522

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The role of iNOS-mediated DNA damage in infection and asbestos-induced carcinogenesis2010

    • Author(s)
      Hiraku Y, Kawanishi S, Ichinose T, Murata M
    • Journal Title

      Ann.NY Acad.Sci.

      Volume: 1203 Pages: 15-22

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] シンポジウム2健康長寿社会における学会活動の方向性、がんとエピジェネティクス2013

    • Author(s)
      村田真理子
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢市
    • Related Report
      2012 Final Research Report
  • [Presentation] Melatonin protects against Opisthorchis viverrini-associated cholangiocarcinoma and liver injury in hamsters.2013

    • Author(s)
      Umawadee Laothong, Yusuke Hiraku, ShinjiOikawa, Mariko Murata, Somchai Pinlaor
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢市
    • Related Report
      2012 Final Research Report
  • [Presentation] Identification of dysregulated microRNA in nasopharyngeal carcinoma2013

    • Author(s)
      Shumin Wang, Yingxi Mo, Kaoru Midorikawa, Zhe Zhang, Guangwu Huang, Ning Ma, Yusuke Hiraku, Shinji Oikawa, Mariko Murata.
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢市
    • Related Report
      2012 Final Research Report
  • [Presentation] Up-regulation of GLRX3 is associated with invasion and metastasis in nasopharyngeal carcinoma2013

    • Author(s)
      Bo Hou, Yingxi Mo, Zhe Zhang, Ning Ma, Yusuke Hiraku, Shinji Oikawa, Kaoru Midorikawa, Mariko Murata
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢市
    • Related Report
      2012 Final Research Report
  • [Presentation] Nitrative DNA damage induced by multi-walled carbon nanotube in cultured cells: a comparison with oxidative DNA damage2013

    • Author(s)
      Feiye Guo, Ning Ma, Shosuke Kawanishi, Mariko Murata, Yusuke Hiraku.
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢市
    • Related Report
      2012 Final Research Report
  • [Presentation] 多層カーボンナノチューブによるDNA損傷:肺上皮細胞における8-ニトログアニン生成2013

    • Author(s)
      平工雄介、Feiye Guo、馬寧、川西正祐、村田真理子
    • Organizer
      第12回分子予防環境医学研究会
    • Place of Presentation
      つくば市
    • Related Report
      2012 Final Research Report
  • [Presentation] 多層カーボンナノチューブによるDNA損傷:肺上皮細胞における8-ニトログアニン生成2013

    • Author(s)
      平工雄介
    • Organizer
      第12回分子予防環境医学研究会
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 虚血再灌流後のサル海馬CA1と歯状回(DG)における酸化損傷タンパク質の比較2013

    • Author(s)
      栗本将多
    • Organizer
      第1回日本酸化ストレス学会東海支部
    • Place of Presentation
      名古屋市立大学(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Nitrative DNA damage induced by multi-walled carbon nanotube in cultured cells: a comparison with oxidative DNA damag2013

    • Author(s)
      Feiye Guo
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢大学医学部(金沢市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 東南アジアにおける生活習慣病の現状について:その5年後2013

    • Author(s)
      翠川薫
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢大学医学部(金沢市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 虚血再灌流後のサル海馬CA1と歯状回(DG)における酸化損傷タンパク質の比較2013

    • Author(s)
      栗本将多
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢大学医学部(金沢市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Up-regulation of GLRX3 is associated with invasion and metastasis in nasopharyngeal carcinoma2013

    • Author(s)
      Bo Hou
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢大学医学部(金沢市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] シンポジウム2健康長寿社会における学会活動の方向性、がんとエピジェネティクス2013

    • Author(s)
      村田真理子
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢大学医学部(金沢市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Melatonin protects against Opisthorchis viverrini-associated cholangiocarcinoma and liver injury in hamsters2013

    • Author(s)
      Umawadee Laothong
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢大学医学部(金沢市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 上咽頭癌におけるmicroRNA調節異常の検討2012

    • Author(s)
      王淑民、莫穎禧、翠川薫、張哲、黄光武、馬寧、平工雄介、及川伸二, 村田真理子.
    • Organizer
      第41回日本環境変異原学会
    • Place of Presentation
      静岡市
    • Related Report
      2012 Final Research Report
  • [Presentation] ビルハルツ住血吸虫感染による膀胱癌におけるDNA損傷と幹細胞マーカー2012

    • Author(s)
      大西志保、馬寧、タナン レイヌー、小林 果、平工雄介、及川伸二、村田真理子、川西正祐
    • Organizer
      フォーラム2012 衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋市
    • Related Report
      2012 Final Research Report
  • [Presentation] バレット食道におけるプロトンポンプ阻害剤のMn-SOD発現を介したDNA損傷への効果2012

    • Author(s)
      村田真理子,平工雄介,及川伸二,タナン レイヌー,ピラオール ソムチャイ,馬寧,川西正祐
    • Organizer
      フォーラム2012 衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋市
    • Related Report
      2012 Final Research Report
  • [Presentation] カーボンナノチューブによる細胞内ニトロ化DNA損傷2012

    • Author(s)
      平工雄介、Feiye Guo、馬寧、川西正祐、村田真理子
    • Organizer
      フォーラム2012 衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋市
    • Related Report
      2012 Final Research Report
  • [Presentation] Association of asbestos fiber contents with oxidative and nitrative DNA damage in human lung2012

    • Author(s)
      平工雄介、馬寧、川西正祐、村田真理子
    • Organizer
      第71回日本癌学会総会
    • Place of Presentation
      札幌市
    • Related Report
      2012 Final Research Report
  • [Presentation] Genome-wide DNA Methylation study of Nasopharyngeal Carcinoma in Chinese patients with Epstein-Barr virus infection2012

    • Author(s)
      Yingxi Mo, Kaoru Midorikawa, Ning Ma, Xiaoying Zhou, Guangwu Huang, Zhe Zhang, Yusuke Hiraku, Shinji Oikawa, Mariko Murata.
    • Organizer
      第71回日本癌学会総会
    • Place of Presentation
      札幌市
    • Related Report
      2012 Final Research Report
  • [Presentation] Nitrative DNA damage induced by multi-walled carbon nanotube with different lengths in cultured cells2012

    • Author(s)
      Feiye Guo, Ning Ma, Shosuke Kawanishi, Mariko Murata, Yusuke Hiraku
    • Organizer
      第71回日本癌学会総会
    • Place of Presentation
      札幌市
    • Related Report
      2012 Final Research Report
  • [Presentation] Stromal expression of alpha-smooth muscle actin correlates with SDF-1 in nasopharyngeal carcinoma2012

    • Author(s)
      Shumin Wang, Ning Ma, Shosuke Kawanishi, Yusuke Hiraku, Shinji Oikawa, Ying Xie, Zhe Zhang, Guangwu Huang, Mariko Murata
    • Organizer
      第71回日本癌学会総会
    • Place of Presentation
      札幌市
    • Related Report
      2012 Final Research Report
  • [Presentation] 食品中に含まれる有効成分の安全性評価:酸化促進作用によるDNA損傷性とエストロゲン感受性乳癌細胞の増殖促進作用.2012

    • Author(s)
      大西志保、村田真理子、川西正祐
    • Organizer
      日本社会薬学会第31年会
    • Place of Presentation
      鈴鹿市
    • Related Report
      2012 Final Research Report
  • [Presentation] Cytosine methylation in EBV-mediated nasopharyngeal carcinoma in relati on to nitrative stress.2012

    • Author(s)
      Yingxi Mo, Ning Ma, Shumin Wang, Zhe Zhang, Ying Xie, Guangwu Huang, Kaoru Midorikawa, Yusuke Hiraku, Shinji Oikawa Shosuke Kawanishi, Mariko Murata
    • Organizer
      The 7th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Edinburgh, UK
    • Related Report
      2012 Final Research Report
  • [Presentation] Nitrative DNA damage in human lung tissues in association with asbestos exposure2012

    • Author(s)
      Yusuke Hiraku, Kiyoshi Sakai, Eiji Shibata, Michihiro Kamijima, Naomi Hisanaga, Ning Ma, Shosuke Kawanishi, Mariko Murata
    • Organizer
      The 7th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Edinburgh, UK
    • Related Report
      2012 Final Research Report
  • [Presentation] Arsenic-induced nitrative DNA damage in human HaCaT kerationcytes2012

    • Author(s)
      Ning Ma, Shiwen Huang, Feiye Guo, Songchao Guo, Mariko Murata, Shosuke Kawanishi
    • Organizer
      The 7th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Edinburgh, UK
    • Related Report
      2012 Final Research Report
  • [Presentation] Nitrative DNA damage in human lung epithelial cells treated with multi-walled carbon nanotube2012

    • Author(s)
      Feiye Guo, Ning Ma, Shosuke Kawanishi, Mariko Murata, Yusuke Hiraku
    • Organizer
      The 7th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Edinburgh, UK
    • Related Report
      2012 Final Research Report
  • [Presentation] Protein carbonylation in liver fluke-induced cholangiocarcinoma in relation to poor prognosis2012

    • Author(s)
      Raynoo Thanan, Shinji Oikawa, Puangrat Yongvanit, Yusuke Hiraku, Ning Ma, Somchai Pinlaor, Chawalit Pairojkul, Chaisiri Wongkham, Banchob Sripa, Shosuke Kawanishi and Mariko Murata.
    • Organizer
      Mahidol International Conference on Infection and Cancer
    • Place of Presentation
      Bangkok, Thailand
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] ヒト肺組織における石綿繊維量と酸化・ニトロ化DNA損傷およびDNA修復酵素発現との関連2012

    • Author(s)
      平工雄介
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 酸化ストレス暴露サル海馬歯状回におけるタンパク質の発現変動2012

    • Author(s)
      栗本将多
    • Organizer
      第65回日本酸化ストレス学会学術集会
    • Place of Presentation
      あわぎんホール徳島郷土文化会館(徳島市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 多層カーボンナノチューブによる細胞内8-ニトログアニン生成2012

    • Author(s)
      平工雄介
    • Organizer
      第12回日本NO学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Cytosine methylation in EBV-mediated nasopharyngeal carcinoma in relation to nitrative stress2012

    • Author(s)
      Yingxi Mo
    • Organizer
      The 7th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Edinburgh University(Edinburgh, UK)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Nitrative DNA damage in human lung tissues in association with asbestos exposure2012

    • Author(s)
      Yusuke Hiraku
    • Organizer
      The 7th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Edinburgh University(Edinburgh, UK)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Arsenic-induced nitrative DNA damage in human HaCaT kerationcytes2012

    • Author(s)
      Ning Ma
    • Organizer
      The 7th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Edinburgh University(Edinburgh, UK)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Nitrative DNA damage in human lung epithelial cells treated with multi-walled carbon nanotube2012

    • Author(s)
      Feiye Guo
    • Organizer
      The 7th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      Edinburgh University(Edinburgh, UK)
    • Related Report
      2012 Annual Research Report
  • [Presentation] プロテオミクス解析による酸化ストレス暴露サル海馬におけるタンパク質の変動解析2012

    • Author(s)
      栗本将多
    • Organizer
      第63回日本電気泳動学総会
    • Place of Presentation
      沖縄コンベンションセンター(宜野湾市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 食品中に含まれる有効成分の安全性評価:酸化促進作用によるDNA損傷性とエストロゲン感受性乳癌細胞の増殖促進作用2012

    • Author(s)
      大西志保
    • Organizer
      日本社会薬学会第31年会
    • Place of Presentation
      鈴鹿医療科学大学(鈴鹿市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 食品中に含まれる有効成分の安全性評価 その1:カテキン類によるDNA損傷性2012

    • Author(s)
      古川絢子
    • Organizer
      日本社会薬学会第31年会
    • Place of Presentation
      鈴鹿医療科学大学(鈴鹿市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Association of asbestos fiber contents with oxidative and nitrative DNA damage in human lung2012

    • Author(s)
      平工雄介
    • Organizer
      第71回日本癌学会総会
    • Place of Presentation
      ロイトン札幌(札幌市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Genome-wide DNA methylation study of nasopharyngeal carcinoma in Chinese patients with Epstein-Barr virus infection2012

    • Author(s)
      Yingxi Mo
    • Organizer
      第71回日本癌学会総会
    • Place of Presentation
      ロイトン札幌(札幌市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Nitrative DNA damage induced by multi-walled carbon nanotube with different lengths in cultured cells2012

    • Author(s)
      Feiye Guo
    • Organizer
      第71回日本癌学会総会
    • Place of Presentation
      ロイトン札幌(札幌市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Stromal expression of alpha-smooth muscle actin correlates with SDF-1 in nasopharyngeal carcinoma2012

    • Author(s)
      Shumin Wang
    • Organizer
      第71回日本癌学会総会
    • Place of Presentation
      ロイトン札幌(札幌市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 虚血再灌流後のサル海馬CA1と歯状回 (DG)における酸化損傷タンパク質の比較2012

    • Author(s)
      栗本将多
    • Organizer
      第21回「海馬と高次脳機能」学会
    • Place of Presentation
      金沢湯涌創作の森(金沢市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] バレット食道におけるプロトンポンプ阻害剤のMn-SOD発現を介したDNA損傷への効果2012

    • Author(s)
      村田真理子
    • Organizer
      フォーラム2012 衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋観光ホテル(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ビルハルツ住血吸虫感染による膀胱癌におけるDNA損傷と幹細胞マーカー2012

    • Author(s)
      大西志保
    • Organizer
      フォーラム2012 衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋観光ホテル(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] カーボンナノチューブによる細胞内ニトロ化DNA損傷2012

    • Author(s)
      平工雄介
    • Organizer
      フォーラム2012 衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋観光ホテル(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 多層カーボンナノチューブによる細胞内DNA損傷の解析(第2報) 繊維長の影響2012

    • Author(s)
      平工雄介
    • Organizer
      日本産業衛生学会東海地方会
    • Place of Presentation
      じゅうろくプラザ(岐阜市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 上咽頭癌におけるmicroRNA調節異常の検討2012

    • Author(s)
      王 淑民
    • Organizer
      第41回日本環境変異原学会
    • Place of Presentation
      グランシップ(静岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] プロテオミクス解析による虚血再灌流後のサル海馬歯状回におけるタンパク質の変動2012

    • Author(s)
      栗本将多、山嶋哲盛、村田真理子、及川伸二
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都
    • Related Report
      2011 Annual Research Report
  • [Presentation] 虚血再灌流後のサル黒質におけるカルボニル化タンパク質の同定2012

    • Author(s)
      及川伸二、栗本将多、小林果、村田真理子、山嶋哲盛
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒト肺組織における石綿繊維量とDNA損傷との関連2012

    • Author(s)
      平工雄介、酒井潔、柴田英治、上島通浩、久永直見、馬寧、川西正祐、村田真理子
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都
    • Related Report
      2011 Annual Research Report
  • [Presentation] 多層カーボンナノチューブによる細胞内ニトロ化DNA損傷:繊維長との関連2012

    • Author(s)
      Feiye Guo、馬寧、川西正祐、村田真理子、平工雄介
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都
    • Related Report
      2011 Annual Research Report
  • [Presentation] RRAD with tumor suppressive function is aberrantly methylated in nasopharyngeal carcinoma2012

    • Author(s)
      Yingxi Mo, Kaoru Midorikawa, Zhe Zhang, Xiaoying Zhou, Guangwu Huang, Ning Ma, Yusuke Hirakul, Shinji Oikawa, Mariko Murata
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都
    • Related Report
      2011 Annual Research Report
  • [Presentation] 上咽頭癌におけるTFPI-2プロモーター領域のメチル化によるがん抑制機能の不活化2012

    • Author(s)
      王淑民、莫穎禧、翠川薫、張哲、黄光武、馬寧、平工雄介、及川伸二、村田真理子
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都
    • Related Report
      2011 Annual Research Report
  • [Presentation] 多層カーボンナノチューブによる細胞内DNA損傷の解析2011

    • Author(s)
      平工雄介、Feiye Guo、村田真理子
    • Organizer
      日本産業衛生学会東海地方会
    • Place of Presentation
      豊明市
    • Year and Date
      2011-11-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] Parasite infection induces oxidative/nitrative DNA damage in stem-like cells in relation to carcinogenesis2011

    • Author(s)
      Raynoo Thanan, Mariko Murata, Ning Ma,Yusuke Hiraku, Shinji Oikawa Shosuke Kawanishi.
    • Organizer
      第70回日本癌学会総会
    • Place of Presentation
      名古屋市
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] 乳癌治療薬タモキシフェンによる子宮内膜発がん機構の検討2011

    • Author(s)
      中村朱里、翠川薫、平工雄介、及川伸二、福原潔、川西正祐、村田真理子
    • Organizer
      第81回日本衛生学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] ヒト肺上皮細胞におけるカーボンブラックナノ粒子によるニトロ化DNA損傷2011

    • Author(s)
      平工雄介、西川嘉広、馬寧、川西正祐、村田真理子
    • Organizer
      第11回日本NO学会学術集会
    • Place of Presentation
      町田市
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒト肺組織における酸化・ニトロ化DNA損傷と石綿曝露との関連2011

    • Author(s)
      平工雄介、酒井潔、柴田英治、上島通浩、久永直見、村田真理子
    • Organizer
      第84回日本産業衛生学会
    • Place of Presentation
      東京(優秀演題)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 多層カーボンナノチューブで処理したヒト肺上皮細胞におけるニトロ化DNA損傷2011

    • Author(s)
      Feiye Guo、馬寧、川西正祐、村田真理子、平工雄介
    • Organizer
      第70回日本癌学会総会
    • Place of Presentation
      名古屋市
    • Related Report
      2011 Annual Research Report
  • [Presentation] Epigenetic aberration of RRAD gene in nasopharyngeal carcinoma and NPC genome-wide methylation profile2011

    • Author(s)
      Yingxi Mo, Kaoru Midorikawa, Ning Ma, Yusuke Hiraku, Shinji Oikawa, Xue Xiao, Xiaoying Zhou, Guangwu Huang, Zhe Zhang, Mariko Murata
    • Organizer
      第70回日本癌学会総会
    • Place of Presentation
      名古屋市
    • Related Report
      2011 Annual Research Report
  • [Presentation] Epigenetic inactivation of paracrined-FSTL1 modulates macrophage functions in nasopharyngeal carcinoma2011

    • Author(s)
      Xue Xiao, Xiaoying Zhou, Yingxi Mo, Guangwu Huang, Shumin Wang, Tingting Huang, Nana Yu, Chunping Du, Wensheng Wen, Mariko Murata, Ning Ma, Ingemar Ernberg, Zhe Zhang
    • Organizer
      第70回日本癌学会総会
    • Place of Presentation
      名古屋市
    • Related Report
      2011 Annual Research Report
  • [Presentation] Genome-wide profiling of DNA methylation identifies epigenetic targets and aberrant methylation of TFPI2 in nasopharyngeal carcinoma2011

    • Author(s)
      Yingxi Mo, Shuming Wang, Kaoru Midorikawa, Zhe Zhang, Guangwu Huang, Ning Ma, Yusuke Hiraku, Shinji Oikawa, Mariko Murata
    • Organizer
      40^<th> Annual Meeting of the Japanese Environmental Mutagen Society
    • Place of Presentation
      東京(ベストプレゼンテーション賞)
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒト肺上皮細胞におけるカーボンブラックによる8-ニトログアニン生成2011

    • Author(s)
      西川嘉広、馬寧、川西正祐、村田真理子、平工雄介
    • Organizer
      第81回日本衛生学会総会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] Oxidative modification of alpha 1-antitrypsin in intrahepatic cholangiocarcinoma2010

    • Author(s)
      Raynoo Thanan, Shinji Oikawa, Yusuke Hiraku, Ning Ma, Shosuke Kawanishi,Mariko Murata.
    • Organizer
      39th JEMS 2010 conference.日本環境変異原学会第39回大会
    • Place of Presentation
      つくば市
    • Related Report
      2012 Final Research Report
  • [Presentation] DNA damage in CD133-positive progenitor cells in liver fluke-induced cholangiocarcinoma.2010

    • Author(s)
      Raynoo Thanan, Mariko Murata, Yusuke Hiraku, Shinji Oikawa, Shosuke Kawanishi
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪市
    • Related Report
      2012 Final Research Report
  • [Presentation] Epstein-Barr virus感染上咽頭癌における酸化ストレスと脂肪組織酸化ストレス軽減効果2010

    • Author(s)
      村田真理子
    • Organizer
      第80回日本衛生学会総会、酸化ストレス研究会企画シンポジウム
    • Place of Presentation
      仙台市
    • Related Report
      2012 Final Research Report
  • [Presentation] DNA damage in CD133-positive progenitor cells in liver fluke-induced cholangiocarcinoma2010

    • Author(s)
      Thanan R, Murata M, Hiraku Y, Oikawa S, Kawanishi S
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪市
    • Related Report
      2010 Annual Research Report
  • [Presentation] Oxidative modification of alpha 1-antitrypsin in intrahepatic cholangiocarcinoma2010

    • Author(s)
      Thanan R, Oikawa S, Hiraku Y, Ma N, Kawanishi S, Murata M
    • Organizer
      日本環境変異原学会第39回大会
    • Place of Presentation
      つくば市
    • Related Report
      2010 Annual Research Report
  • [Presentation] iNOS-mediated DNA damage induced by nanoparticles : 8-nitroguanine formation in cultured cells treated with carbon black2010

    • Author(s)
      Hiraku Y, Ishiyama R, Matsunaga Y, Horibe Y, Ma N, Kawanishi S, Murata M
    • Organizer
      The 6th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      京都市
    • Related Report
      2010 Annual Research Report
  • [Presentation] Tumor microenvironment & Oncogenesis", Formation of 8-nitroguanine, a DNA lesion associated with inflammation-related carcinogenesis, in human lung in relation to asbestos exposure2010

    • Author(s)
      Hiraku Y, Sakai K, Shibata E, Kamijima M, Hisanaga N, Ma N, Kawanishi S, Murata M
    • Organizer
      The 10th International Conference of the International Mesothelioma Interest Group
    • Place of Presentation
      京都市
    • Related Report
      2010 Annual Research Report
  • [Book] 8-Nitroguanine: A potential biomarker to evaluate the risk of inflammation-related carcinogenesis2012

    • Author(s)
      Ma N, Murata M, Ohnishi S, Thanan R, Hiraku Y, Kawanishi S
    • Publisher
      Biomarker. Khan TK (ed.). InTech
    • Related Report
      2012 Final Research Report
  • [Book] In: Biomarker. Khan TK (ed.). InTech2012

    • Author(s)
      Ma N
    • Publisher
      8-Nitroguanine: A potential biomarker to evaluate the risk of inflammation-related carcinogenesis.
    • Related Report
      2012 Annual Research Report
  • [Book] 第1章 がんの生物学、腫瘍薬学(川西正祐、他 編)2010

    • Author(s)
      村田哲也、村田真理子
    • Publisher
      南山堂
    • Related Report
      2012 Final Research Report
  • [Book] 第5章 子どもの病気とその予防、子どもの保健-理論と実践-2010

    • Author(s)
      谷口アキ、村田真理子
    • Publisher
      日本小児医事出版社、第6版
    • Related Report
      2012 Final Research Report
  • [Book] 第1章がんの生物学、腫瘍薬学(川西正祐、他編)2010

    • Author(s)
      村田哲也、村田真理子
    • Publisher
      南山堂
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.medic.mie-u.ac.jp/eiseigaku/

    • Related Report
      2012 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi