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Investigation of pathogenesis and establishment of a new diagnostic system for hand-arm vibration syndrome

Research Project

Project/Area Number 22390125
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Hygiene
Research InstitutionYamaguchi University

Principal Investigator

HARADA Noriaki  山口大学, 大学院・医学系研究科, 教授 (70116747)

Co-Investigator(Kenkyū-buntansha) TANIGAWA Kazuko  宇部フロンティア大学, 人間社会学部, 教授 (00321224)
MIYASHITA Kazuhisa  和歌山県立医科大学, 医学部, 教授 (50124889)
KUROZAWA Youichi  鳥取大学, 医学部, 教授 (50161790)
ISHITAKE Tatuya  久留米大学, 医学部, 教授 (60232295)
MAHBUB Hossain Md  山口大学, 大学院・医学系研究科, 講師 (80535336)
戸ヶ里 泰典  放送大学, 教養学部, 准教授 (20509525)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
Fiscal Year 2012: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2011: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2010: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
Keywords手腕振動症候群 / 病態 / 診断 / ガイドライン
Research Abstract

The diagnostic system for hand-arm vibration syndrome is different among countries. The system being used in Japan was established nearly 40 years ago; it needs to be revised according to the new and recent scientific knowledge in this and relevant fields. The aim of this study is to propose a new diagnostic system through the working group activities of the Research Society for Vibration Syndrome together with several investigations to update the findings on the pathogenesis of hand-arm vibration syndrome by analyzing blood samples collected during an epidemiological study conducted 25 years ago, and diagnostic test procedures using newly developed equipments. The working group meetings were held 7 times during these three years to discuss the results of subgroup activity. The findings were re-discussed at the meetings of the Research Society for Vibration Syndrome and reported at several scientific meetings both inside and outside of Japan. As the result, a new diagnostic guideline for hand-arm vibration syndrome 2013 has been established. It is being submitted to scientific journals and posted at the homepage of the Research Society for Vibration Syndrome; print versions are under preparation for distribution.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (32 results)

All 2013 2012 2011 2010

All Journal Article (22 results) (of which Peer Reviewed: 15 results) Presentation (10 results)

  • [Journal Article] Effects of whole-body vibration on postural balance and proprioception in healthy young and elderly subjects: a randomized cross-over study2013

    • Author(s)
      Hiroshige K
    • Journal Title

      Journal of Sports Medicine and Physical Fitness

      Volume: 印刷中

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 振動暴露作業者の健康管理における新しい診断体系の確立に関する研究2012

    • Author(s)
      原田規章、榊原久孝、黒沢洋一、石竹達也、樋端規邦、佐藤修二、久米行則、
    • Journal Title

      産業医学ジャーナル

      Volume: 35(5) Pages: 58-62

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 全身振動の職業的曝露と健康の関連性-主に背腰部症状について2012

    • Author(s)
      西山勝夫、原田規章、辻村裕次、石竹達也、榊原久孝、松本泰尚
    • Journal Title

      産業衛生学誌

      Volume: 54 (4) Pages: 121-140

    • NAID

      10030495788

    • Related Report
      2012 Final Research Report
  • [Journal Article] Effects of whole-body vibration on postural balance and proprioception in healthy young and elderly subjects: a randomized cross-over study2012

    • Author(s)
      Hiroshige K, Mahbub MH, Harada N
    • Journal Title

      Journal of Sports Medicine and Physical Fitness

    • Related Report
      2012 Final Research Report
  • [Journal Article] Diagnostic accuracy of quantitative tests to assess upper limb musculoskeletal disorders and impaired dexterity in HAVS: a systematic review2012

    • Author(s)
      Mahbub MH, Kurozawa Y, Ishitake T, Kume Y, Miyashita K, Sakakibara H, Sato S, Toibana N, Harada N
    • Journal Title

      Proceedings of the 47th UK Conference on Human Responses to Vibration, Southampton, UK

      Pages: 107-114

    • Related Report
      2012 Final Research Report
  • [Journal Article] Neuromuscular responses to acute whole body vibration in healthy young men2012

    • Author(s)
      Hiroshige K, Mahbub MH, Harada N
    • Journal Title

      The Bulletin of the Yamaguchi Medical School

      Volume: 59(1-2) Pages: 15-24

    • NAID

      120004680896

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 振動暴露作業者の健康管理における新しい診断体系の確立に関する研究2012

    • Author(s)
      原田規章
    • Journal Title

      産業医学ジャーナル

      Volume: 35巻 5号 Pages: 58-62

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 全身振動の職業的曝露と健康の関連性―主に背腰部症状について2012

    • Author(s)
      西山勝夫
    • Journal Title

      日本産業衛生学雑誌

      Volume: 54巻 4号 Pages: 121-140

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Diagnostic accuracy of quantitative tests to assess upper limb musculoskeletal disorders and impaired dexterity in HAVS: a systematic review2012

    • Author(s)
      Mahbub MH
    • Journal Title

      Proceedings of the 47th UK Conference on Human Responses to Vibration, Southampton, UK

      Volume: ─ Pages: 107-114

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Neuromuscular responses to acute whole body vibration in healthy young men2012

    • Author(s)
      Hiroshige K
    • Journal Title

      The Bulletin of the Yamaguchi Medical School

      Volume: 59 1-2 Pages: 15-24

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Review of different quantification methods for the diagnosis of digital vascular abnormalities in hand-arm vibration syndrome2011

    • Author(s)
      Mahbub MH, Harada N
    • Journal Title

      Journal of Occupational Health

      Volume: 53(4) Pages: 241-249

    • NAID

      10029139601

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] New standard criteria for cold provocation test with hand immersion for cases of HAVS in Japan2011

    • Author(s)
      Ishitake T, Sato S, Kume Y, Nagase T, Sakakibara H, Toibana N, Kurozawa Y, Miyashita K, Mahbub MH, Harada N
    • Journal Title

      Canadian Acoustics

      Volume: 39(2) Pages: 30-31

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of cold immersion tests with water at 12°C and 10°C for 5 min in diagnosing vibration-induced white finger2011

    • Author(s)
      Mahbub MH, Ishitake T, Kurozawa Y, Toibana N, Harada N
    • Journal Title

      Canadian Acoustics

      Volume: 39(2) Pages: 74-75

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Guidelines of the Japanese research society for vibration syndrome to diagnose hand-arm vibration syndrome2011

    • Author(s)
      Harada N, Hirata M , Ishitake T, Kume Y, Kurozawa Y, Miyashita K, Sakakibara H, Sato S, Toibana N, Mahbub MH
    • Journal Title

      Canadian Acoustic

      Volume: 39(2) Pages: 76-77

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Diagnostic performance of cold provocation test with hands immersion in water at 10°C for 5 min evaluated in vibration-induced white finger patients and matched controls2011

    • Author(s)
      Mahbub MH, Ishitake T, Kurozawa Y, Toibana N, Ide F, Ohnari H, Tanigawa K, Takahashi Y, Harada N
    • Journal Title

      Int Arch Occup Environ Health

      Volume: 84(7) Pages: 805-811

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Vibrotactile perception at glabrous and nonglabrous skin of fingers: repeatability of measurements and changes induced by acute vibration exposure2011

    • Author(s)
      Mahbub M, Ohnari H, Tanigawa K, Hiroshige K, Takahashi Y, Togari T, Harada N
    • Journal Title

      Journal of Occupational Health

      Volume: 53(1) Pages: 10-15

    • NAID

      10027417137

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of cold immersion tests with water at 12℃ and 10℃ for 5 min in diagnosing vibration-induced white finger2011

    • Author(s)
      Mahbub MH, Ishitake T, Kurozawa Y, Toibana N, Harada N
    • Journal Title

      Canadian Acoustics

      Volume: 39(2) Pages: 74-75

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Guidelines of the Japanese research society for vibration syndrome to diagnose hand-arm vibration syndrome2011

    • Author(s)
      Harada N, Hirata M, Ishitake T, Kume Y, Kurozawa Y, Miyashita K, Sakakibara H, Sato S, Toibana N
    • Journal Title

      Canadian Acoustics

      Volume: 39(2) Pages: 76-77

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diagnostic performance of cold provocation test with hands immersion in water at 10℃ for 5 min evaluated in vibration-induced white finger patients and matched controls2011

    • Author(s)
      Mahbub MH, Ishitake T, Kurozawa Y, Toibana N, Ide F, Ohnari H, Tanigawa K, Takahashi Y, Harada N
    • Journal Title

      Int Arch Occup Environ Health

      Volume: 84(7) Pages: 805-8011

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Vibrotactile perception at glabrous and nonglabrous skin of fingers : repeatability of measurements and changes induced by acute vibration exposure2011

    • Author(s)
      Mahbub M, Ohnari H, Tanigawa K, Hiroshige K, Takahashi Y, Togari T, Harada N
    • Journal Title

      J Occup Health

      Volume: 53(1) Pages: 10-15

    • NAID

      10027417137

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Assessing the diagnostic accuracy of cold provocation test with hands immersion in water at 10°C for 5 min in diagnosing vibration-induced white finger2010

    • Author(s)
      Mahbub MH, Ishitake T, Kurozawa Y, Toibana N, Ide F, Takahashi Y, Harada N
    • Journal Title

      Proceedings of the 18th Japan Conference on Human Response to Vibration

      Pages: 1-7

    • Related Report
      2012 Final Research Report
  • [Journal Article] Assessing the diagnostic accuracy of cold provocation test with hands immersion in water at 10℃ for 5 min in diagnosing vibration-induced white finger2010

    • Author(s)
      Mahbub MH, Ishitake T, Kurozawa Y, Toibana N, Ide F, Takahashi Y, Harada N
    • Journal Title

      Proceedings of the 18th Japan Conference on Human Response to Vibration

      Pages: 1-7

    • Related Report
      2010 Annual Research Report
  • [Presentation] 振動障害患者における温度・温痛覚閾値検査の有効性2012

    • Author(s)
      石竹達也、佐藤修二、星子美智子
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Year and Date
      2012-06-01
    • Related Report
      2012 Final Research Report
  • [Presentation] 手腕振動症候群の筋骨格系傷害を評価するうえでの種々の臨床試験の診断的精度:システマティックレビュー2012

    • Author(s)
      Mahbub Hossain、黒沢洋一、石竹達也、久米行則、宮下和久、榊原久孝、佐藤修二、樋端規邦、原田規章
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Year and Date
      2012-06-01
    • Related Report
      2012 Final Research Report
  • [Presentation] 手腕振動症候群の筋骨格系傷害を評価するうえでの種々の臨床試験の診断的精度:システマティックレビュー2012

    • Author(s)
      Mahbub Hossain
    • Organizer
      日本産業衛生学会
    • Place of Presentation
      名古屋市(名古屋国際会議場)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effects of vibration exposure from grasping a vibrating handle on finger thermotactile perception in healthy subjects2011

    • Author(s)
      Shuichiro Ohata, Hossain Mahbub, Tatsuo Sakamoto, Meng Han, Noriaki Harada
    • Organizer
      第55回中国四国合同産業衛生学会
    • Place of Presentation
      高知市総合あんしんセンター、高知市
    • Year and Date
      2011-12-11
    • Related Report
      2012 Final Research Report
  • [Presentation] 振動障害における手指温冷覚閾値検査法の検討2011

    • Author(s)
      佐藤修二、星子美智子、石竹達也
    • Organizer
      第84回日本産業衛生学会
    • Place of Presentation
      東京都立産業貿易センター、東京
    • Year and Date
      2011-05-18
    • Related Report
      2012 Final Research Report
  • [Presentation] 振動障害患者における手指温冷覚閾値2011

    • Author(s)
      石竹達也
    • Organizer
      第84回日本産業衛生学会
    • Place of Presentation
      東京都立産業貿易センター、東京
    • Year and Date
      2011-05-18
    • Related Report
      2012 Final Research Report
  • [Presentation] シンポジウム:振動障害による健康障害予防の新しい展開とその評価 35年を経た改定と国内外の動向振動障害研究会における新しい診断体系の検討2010

    • Author(s)
      石竹達也
    • Organizer
      第83回日本産業衛生学会
    • Place of Presentation
      福井県国際交流会館、福井市
    • Year and Date
      2010-05-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 振動障害における手指温冷感覚閾値検査法の検討2010

    • Author(s)
      佐藤修二、安藤英雄、星子美智子、石竹達也
    • Organizer
      第83回日本産業衛生学会
    • Place of Presentation
      フェニックスプラザ、福井市
    • Year and Date
      2010-05-26
    • Related Report
      2012 Final Research Report
  • [Presentation] 手指掌側および背側における振動感覚閾値:測定再現性と急性振動暴露による変動2010

    • Author(s)
      マハブブホセイン、大成博音、谷川和子、廣滋恵一、高橋幸雄、戸ヶ里泰典、原田規章
    • Organizer
      第83回日本産業衛生学会
    • Place of Presentation
      フェニックスプラザ、福井市
    • Year and Date
      2010-05-26
    • Related Report
      2012 Final Research Report
  • [Presentation] Vibrotactile perception at palmar and dorsal skin of fingers : repeatability of measurements and changes induced by acute vibration exposure2010

    • Author(s)
      M.H.Mahbub
    • Organizer
      第83回日本産業衛生学会
    • Place of Presentation
      フェニックス・プラザ、福井県国際交流会館(福井県)
    • Year and Date
      2010-05-26
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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