Development and establishment of the novel method for the objective diagnosis of Meniere's disease using advanced MRI techniques
| Project/Area Number |
22390233
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKASHIMA Tsutomu 名古屋大学, 大学院・医学系研究科, 教授 (30180277)
NIHASHI Takashi 名古屋大学, 医学部附属病院, 講師 (00426496)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥14,430,000 (Direct Cost: ¥11,100,000、Indirect Cost: ¥3,330,000)
Fiscal Year 2012: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2010: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
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| Keywords | 磁気共鳴医学 / 耳科学 / 高磁場 / 造影剤 / メニエール病 / 磁気共鳴画像 / 受信コイル / 内リンパ / 外リンパ / ガドリニウム造影剤 / 内リンパ永腫 / 内耳疾患 / めまい / 難聴 |
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| Research Abstract |
To develop less invasive and robust objective diagnostic method for Meniere’s disease, we developed various methods as follows; custom built dedicated four channel coil which has 2 times SNR compared to commercial coil. Optimal timing of imaging after iv-Gd was 3.5h-4.5h. We developed positive endolymph image (PEI). For the image processing, we developed a method to separately visualize bone, endolymph and perilymph on a single image. We subtractPEI from PPI, resulting in the HYDROPS image. We also developed HYDROPS2 image etc by the subtraction of T2 from PPI. Additionally, we succeeded the semi-quantification of endolymph size by iv-Gd.
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Report
(4 results)
Research Products
(122 results)
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[Journal Article] A perspective from magnetic resonance imaging findings of the inner ear: Relationships among cerebrospinal, ocular and inner ear fluids2012
Author(s)
Nakashima T, Sone M, Teranishi M, Yoshida T, Terasaki H, Kondo M, Yasuma T, Wakabayashi T, Nagatani T, Naganawa S
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Journal Title
Auris NasusLarynx
Volume: 39(4)
Pages: 345-55
Related Report
Peer Reviewed
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[Journal Article] Putaminal magnetic resonance imaging features at various magnetic field strengths in multiple system atrophy.2010
Author(s)
Watanabe H, Ito M, Fukatsu H, Senda J, Atsuta N, Kaga T, Kato S, Katsuno M, Tanaka F, Hirayama M, Naganawa S, Sobue G.
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Journal Title
Mov Disord
Volume: 15;25(12)
Pages: 1916-1923
Related Report
Peer Reviewed
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[Journal Article] Diagnostic value of SPIO-mediated breath-hold, black-blood, fluid-attenuated, inversion recovery (BH-BB-FLAIR) imaging in patients with hepatocellular carcinomas.2010
Author(s)
Matsushima M, Naganawa S, Ikeda M, Itoh S, Ogawa H, Komada T, Ishigaki S, Kawai H, Suzuki K, Satake H, Iwano S.
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Journal Title
Magn Reson Med Sci
Volume: 9
Pages: 49-58
Related Report
Peer Reviewed
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