Research Project
Grant-in-Aid for Scientific Research (B)
Trastuzumab, a humanized antibody targeting HER2, exhibits remarkable therapeutic efficacy against HER2-positive breast and gastric cancers. We found that exogenous HER2-extracellular domain (ECD) expression had no apparent effect on the signaling pathway, but strongly enhanced antibody-dependent cellular cytotoxicity (ADCC) activity in low HER2-expressing or trastuzumab-resistant human cancer cells.
All 2013 2012 2011 2010
All Journal Article (30 results) (of which Peer Reviewed: 30 results) Presentation (16 results) (of which Invited: 1 results) Book (1 results)
PLoS One
Volume: (inpress)
120005232484
Cancer Chemother. Pharmacol
Volume: 71 Pages: 937-943
Int. J. Cancer
Volume: 132 Pages: 2705-2713
Dual programmed cell death pathways induced by p53 transactivation overcome resistance to oncolytic adenovirus in human osteosarcoma cells.
Volume: 12 Pages: 314-325
120005324798
Gene Ther.
Volume: 20 Pages: 112-118
Molecular Cancer Therapeutics
Volume: 12 Issue: 3 Pages: 314-325
10.1158/1535-7163.mct-12-0869
Eur. J. Cancer
Volume: 48 Pages: 2282-2291
Volume: 131 Pages: 2939-2950
130004505785
Cancer Immuno. Immunother.
Volume: 61 Pages: 1905-1916
120005232490
Cancer Gene Ther.
Volume: 19 Pages: 767-772
Cancer Immunology, Immunotherapy
Volume: 61 Issue: 11 Pages: 1905-1916
10.1007/s00262-012-1249-x
European Journal of Cancer
Volume: (Epub ahead of print) Issue: 14 Pages: 2282-2291
10.1016/j.ejca.2011.12.020
International Journal of Cancer
Volume: (Epub ahead of print) Issue: 12 Pages: 2939-2950
10.1002/ijc.27589
Cancer Gene Therapy
Volume: 19 Issue: 11 Pages: 767-772
10.1038/cgt.2012.57
Gene Therapy
Volume: (Epub ahead of print) Issue: 1 Pages: 112-118
10.1038/gt.2011.213
Clin. Cancer Res.
Volume: 17 Pages: 1828-1838
130004505755
Volume: 17 Pages: 2807-2818
Cancer Sci.
Volume: 102 Pages: 1344-1349
10029295354
Cell Cycle
Volume: 10 Pages: 2737-2741
Expert Opinion on Biological Therapy
Volume: 11 Issue: 2 Pages: 145-155
10.1517/14712598.2011.542749
Clinical Cancer Research
Volume: 17 Issue: 7 Pages: 1828-1838
10.1158/1078-0432.ccr-10-2066
Expert Review of Anticancer Therapy
Volume: 11 Issue: 4 Pages: 525-532
10.1586/era.10.200
Mol. Ther.
Volume: 18 Pages: 429-34
Oncogene
Volume: 29 Pages: 1145-1154
Ann. Surg.
Volume: 251 Pages: 1079-1086
Mol. Cancer Ther.
Volume: 9 Pages: 1884-1893
Cancer Res.
Volume: 70 Pages: 9339-9348
Annals of Surgery
Molecular Cancer Terapeutics
Cancer Research