Budget Amount *help |
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2010: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
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Research Abstract |
A pilot study for an anti-adhesive membrane for thoracic surgeries especially for the pleural cavity surgery was performed. A biodegradable membrane made of gelatin or hyaluronic-acid containing a certain amount of glycerin was developed. In vivo and in vitro studies showed that the tested membranes were effective to prevent adhesion in the pleural cavity. The mechanism of these desirable results was as follows. The membranes contained glycerin, which gathered and dispersed abundant water. Together with this, growth factors are also dispersed, resulting in dilution of excessive growth factors at the wound sites.
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