Basic and clinical research for surgical treatment of unilaterallaryngeal paralysis aiming at reinnervation of the laryngeal muscle

• Project/Area Number: 22390316
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Otorhinolaryngology
• Research Institution: Kumamoto University
• Principal Investigator: YUMOTO Eiji 熊本大学, 生命科学研究部, 教授 (40116992)
• Co-Investigator(Renkei-kenkyūsha): SANUKI Tetsuji 熊本大学, 医学部附属病院, 講師 (10335896) ; KUMAI Yoshihiko 熊本大学, 生命科学研究部, 助教 (00555774) ; MIYAMARU Satoru 熊本大学, 医学部附属病院, 助教 (10535636)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000); Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2010: ¥11,960,000 (Direct Cost: ¥9,200,000、Indirect Cost: ¥2,760,000)
• Keywords: 脳・神経 / 喉頭麻痺 / 反回神経 / 神経再支配 / 神経筋弁

Research Abstract

The nerve-muscle pedicle (NMP) flap implantation immediately aftertransection of the recurrent laryngeal nerve facilitated reinnervation of the denervatedthyroarytenoid muscle. Further, NMP implantation was effective in the recovery fromatrophic changes in long-term denervated thyroarytenoid muscle. The authors performedarytenoid adduction in 10 patients and NMP flap implantation combined with arytenoidadduction in 32 patients during research period. The latter patient group showedtime-dependent improvement of vocal function and most of them retrieved their own voicesbefore the onset of laryngeal paralysis.

Research Products

• [Journal Article] The impact of nimodipineadministration combined with nerve-musclepedicle implantation on long-termdenervated rat thyroarytenoid muscle (2013)
  • Author(s): Nishimoto K, Kumai Y, Sanuki T, MinodaR, Yumoto E
  • Journal Title: Laryngoscope Volume: 123 Pages: 952-959
  • Peer Reviewed
• [Journal Article] Recurrent laryngealnerve regeneration through a silicone tubeproduces reinnervation without vocal foldmobility in rats (2013)
  • Author(s): Kumai Y, Aoyama T, Nishimoto K, SanukiT, Minoda R, Yumoto E
  • Journal Title: Ann Otol Rhinol Laryngol Volume: 122 Pages: 49-53
  • Peer Reviewed
• [Journal Article] Glottal configuration inunilaterally paralyzed larynx and vocalfunction (2013)
  • Author(s): Yumoto E, Sanuki T, Minoda R, Kumai Y,Nishimoto K
  • Journal Title: Acta Otolaryngol Volume: 133 Pages: 187-193
  • Peer Reviewed
• [Journal Article] 陳旧性一側喉頭麻痺に対する披裂軟骨内転術と神経移行術の併用術の経時的効果 (2013)
  • Author(s): 兒玉成博、讃岐徹治、湯本英二
  • Journal Title: 音声言語医学 Volume: 54 Pages: 8-13
  • NAID: 10031143753
  • Peer Reviewed
• [Journal Article] 音声外科手術-声帯ポリープから喉頭麻痺まで (2013)
  • Author(s): 湯本英二
  • Journal Title: 日本耳鼻咽喉科学会会報 Volume: 116 Pages: 34-37
  • NAID: 10031145268
• [Journal Article] 神経再支配を目ざした音声外科 (2013)
  • Author(s): 湯本英二
  • Journal Title: 耳鼻咽喉科・頭頸部外科 Volume: 85 Pages: 98-106
• [Journal Article] Glottal configuration in unilaterally paralyzed larynx and vocal function (2013)
  • Author(s): Yumoto E
  • Journal Title: Acta Otolaryngol Volume: 133 Issue: 2 Pages: 187-193
  • DOI: 10.3109/00016489.2012.726741
  • Peer Reviewed
• [Journal Article] Recurrent laryngeal nerve regeneration through a silicone tube produces reinnervation without vocal fold mobility in rats (2013)
  • Author(s): Kumai Y
  • Journal Title: Ann Otol Rhinol Laryngol Volume: 122 Pages: 49-53
  • Peer Reviewed
• [Journal Article] 一側喉頭麻痺に対する披裂軟骨内転術と神経移行術の併用術の経時的効果 (2013)
  • Author(s): 兒玉成博
  • Journal Title: 音声言語医学 Volume: 54 Pages: 8-13
  • Peer Reviewed
• [Journal Article] 音声外科手術－声帯ポリープから喉頭麻痺まで (2013)
  • Author(s): 湯本英二
  • Journal Title: 日本耳鼻咽喉科学会会報 Volume: 116 Pages: 34-37
  • NAID: 10031145268
• [Journal Article] The Impact of Nimodipine Administration Combined with Nerve-Muscle Pedicle Implantation on Long-Term Denervated Rat Thyroarytenoid Muscle (2013)
  • Author(s): Nishimoto K
  • Journal Title: Laryngoscope Volume: 123 Issue: 4 Pages: 952-959
  • DOI: 10.1002/lary.23698
  • Peer Reviewed
• [Journal Article] Videolaryngoscopic assessmentof laryngeal edema after arytenoidadduction (2012)
  • Author(s): Narajos N, Toya Y, Kumai Y, Sanuki T,Yumoto E
  • Journal Title: Laryngoscope Volume: 122 Pages: 1104-1108
  • Peer Reviewed
• [Journal Article] Nerve-muscle pedicle implantation inthe denervated thyroarytenoid muscle ofaged rats (2012)
  • Author(s): Miyamaru S, Kumai Y, Minoda R, YumotoE
  • Journal Title: Acta Otolaryngol Volume: 132 Pages: 210-217
  • Peer Reviewed
• [Journal Article] Modulation of nerve fibers in the ratthyroarytenoid muscle following recurrentlaryngeal nerve injury (2012)
  • Author(s): Toya Y, Kumai Y, Minoda R, Yumoto E
  • Journal Title: Acta Otolaryngol Volume: 132 Pages: 305-313
  • Peer Reviewed
• [Journal Article] Nimodipine accelerates reinnervationof denervated rat thyroarytenoid musclefollowing nerve-muscle pedicleimplantation (2012)
  • Author(s): Nishimoto K, Kumai Y, Minoda R, YumotoE
  • Journal Title: Laryngoscope Volume: 122 Pages: 606-613
  • Peer Reviewed
• [Journal Article] Vocal outcome after arytenoidadduction and ansa cervicalis transfer (2012)
  • Author(s): Hassan MM, Yumoto E, Kumai Y, Sanuki T,Kodama N
  • Journal Title: Arch Otolaryngol Head Neck Surg Volume: 138 Pages: 60-65
  • Peer Reviewed
• [Journal Article] Videolaryngoscopic assessment of laryngeal edema after arytenoid adduction (2012)
  • Author(s): Narajos N
  • Journal Title: Laryngoscope Volume: 122 Issue: 5 Pages: 1104-1108
  • DOI: 10.1002/lary.23241
  • Peer Reviewed
• [Journal Article] Vocal outcome after arytenoid adduction and ansa cervicalis transfer (2012)
  • Author(s): Hassan MM
  • Journal Title: Arch Otolaryngol Head Neck Surg Volume: 138 Pages: 60-65
  • Peer Reviewed
• [Journal Article] Nimodipine accelerates reinnervation of denervated rat thyroarytenoid muscle following nerve-muscle pedicle implantation (2012)
  • Author(s): Nishimoto K
  • Journal Title: Laryngoscope Volume: 122 Issue: 3 Pages: 606-613
  • DOI: 10.1002/lary.22487
  • Peer Reviewed
• [Journal Article] Nerve-muscle pedicle implantation in the denervated thyroarytenoid muscle of aged rats (2012)
  • Author(s): Miyamaru S
  • Journal Title: Acta Otolaryngol Volume: 132 Issue: 2 Pages: 210-217
  • DOI: 10.3109/00016489.2011.630018
  • Peer Reviewed
• [Journal Article] Modulation of nerve fibers in the rat thyroarytenoid muscle following recurrent laryngeal nerve injury (2012)
  • Author(s): Toya Y
  • Journal Title: Acta Otolaryngol Volume: 132 Issue: 3 Pages: 305-313
  • DOI: 10.3109/00016489.2011.637176
  • Peer Reviewed
• [Journal Article] Arytenoid rotation andnerve-muscle pedicle transfer inparalytic dysphonia (2011)
  • Author(s): Hassan MM, Yumoto E, Baraka A, SanukiT, Kodama N
  • Journal Title: Laryngoscope Volume: 121 Pages: 1018-1022
  • Peer Reviewed
• [Journal Article] 披裂軟骨内転術と併用術式の発声機能評価 (2011)
  • Author(s): 兒玉成博、讃岐徹治、東家 完、湯本英二
  • Journal Title: 音声言語医学 Volume: 52 Pages: 149-157
  • NAID: 10028169964
  • Peer Reviewed
• [Journal Article] Arytenoid Rotation and Nerve-Muscle Pedicle Transfer in Paralytic Dysphonia (2011)
  • Author(s): Hassan MM
  • Journal Title: Laryngoscope Volume: 121 Issue: 5 Pages: 1018-1022
  • DOI: 10.1002/lary.21657
  • Peer Reviewed
• [Journal Article] The role of immediate recurrent laryngealnerve reconstruction for thyroid cancersurgery (2010)
  • Author(s): Sanuki T, Yumoto E, Minoda R, Kodama N
  • Journal Title: J Oncol Volume: 2010 Pages: 846235-846235
  • Peer Reviewed
• [Journal Article] Effects of nerve-musclepedicle on immobile rat vocal folds in thepresence of partial innervation (2010)
  • Author(s): Aoyama T, Kumai Y, Yumoto E, Ito T,Miyamaru S
  • Journal Title: Ann OtolRhinol Laryngol Volume: 119 Pages: 823-829
  • Peer Reviewed
• [Journal Article] Nerve-muscle pedicle flapimplantation combined with arytenoidadduction (2010)
  • Author(s): Yumoto E, Sanuki T, Toya Y, Kodama N,Kumai Y
  • Journal Title: Arch Otolaryngol Head Neck Surg Volume: 136 Pages: 965-969
  • Peer Reviewed
• [Journal Article] 披裂軟骨内転術後の咽喉頭腫脹 (2010)
  • Author(s): 東家 完、湯本英二、讃岐徹治、熊井良彦、西本康兵
  • Journal Title: 音声言語医学 Volume: 51 Pages: 335-340
  • NAID: 10026596867
  • Peer Reviewed
• [Journal Article] 披裂軟骨脱臼の 2 症例 (2010)
  • Author(s): 青山 猛、讃岐徹治、増田聖子、湯本英二
  • Journal Title: 音声言語医学 Volume: 51 Pages: 149-155
  • NAID: 10026252079
  • Peer Reviewed
• [Journal Article] Effects of type II thyroplasty on adductorspasmodic dysphonia (2010)
  • Author(s): Sanuki T, Yumoto E, Minoda R, Kodama N
  • Journal Title: Otolaryngol HeadNeck Surg Volume: 142 Pages: 540-546
  • Peer Reviewed
• [Journal Article] 外来で行う瘢痕声帯に対するステロイド局所注射 (2010)
  • Author(s): 讃岐徹治、熊井良彦、東家 完、西本康兵、兒玉成博、湯本英二
  • Journal Title: 喉 頭 Volume: 22 Pages: 61-66
  • NAID: 10027844317
  • Peer Reviewed
• [Journal Article] Effects of type II thyroplasty on adductor spasmodic dysphonia (2010)
  • Author(s): Sanuki T
  • Journal Title: Otolaryngology-head and neck surgery Volume: 142(4) Pages: 540-546
  • Peer Reviewed
• [Journal Article] 披裂軟骨脱臼の2症例 (2010)
  • Author(s): 青山猛
  • Journal Title: 音声言語医学 Volume: 51 Pages: 149-155
  • Peer Reviewed
• [Journal Article] Nerve-Muscle Pedicle Flap Implantation Combined With Arytenoid Adduction (2010)
  • Author(s): Yumoto E
  • Journal Title: Arch Otolaryngol Head Neck Surg Volume: 136(10) Pages: 965-969
  • Peer Reviewed
• [Journal Article] Effects of Nerve-Muscle Pedicle on Immobile Rat Vocal Folds in the Presence of Partial Innervation (2010)
  • Author(s): Aoyama T
  • Journal Title: Ann Otol Rhinol Laryngol Volume: 119(12) Pages: 823-829
  • Peer Reviewed
• [Journal Article] 外来で行う瘢痕声帯に対するステロイド局所注射 (2010)
  • Author(s): 讃岐徹治
  • Journal Title: 喉頭 Volume: 22(2) Pages: 61-66
  • NAID: 10027844317
  • Peer Reviewed
• [Presentation] 喉頭形成術 (2013)
  • Author(s): 讃岐徹治
  • Organizer: 第25回日本喉頭科学会総会・学術講演会(招待講演)
  • Place of Presentation: 横浜、メルパルク横浜
  • Year and Date: 2013-03-07
• [Presentation] 側反回神経合併切除症例に対する一期的神経再建術の治療効果 (2013)
  • Author(s): 熊井良彦
  • Organizer: 第25回日本喉頭科学会総会・学術講演会
  • Place of Presentation: 横浜、メルパルク横浜
  • Year and Date: 2013-03-07
• [Presentation] 神経筋弁移植術後発声機能と正常声との比較 (2013)
  • Author(s): 兒玉成博
  • Organizer: 25回日本喉頭科学会総会・学術講演会
  • Place of Presentation: 横浜、メルパルク横浜
  • Year and Date: 2013-03-07
• [Presentation] 音声外科手術-とくに披裂軟骨内転術と神経筋弁移植術 (2013)
  • Author(s): 湯本英二
  • Organizer: 第23回日本頭頸部外科学会総会 ・ 学術講演会 (招待講演)
  • Place of Presentation: 鹿児島、城山観光ホテル
  • Year and Date: 2013-01-24
• [Presentation] 音声外科手術-とくに披裂軟骨内転術と神経筋弁移植術 (2013)
  • Author(s): 湯本英二
  • Organizer: 第23回日本頭頸部外科学会総会・学術講演会
  • Place of Presentation: 鹿児島、城山観光ホテル
  • Invited
• [Presentation] 神経筋弁移植術後発声機能と正常声との比較 (2013)
  • Author(s): 兒玉成博
  • Organizer: 第25回日本喉頭科学会総会・学術講演会
  • Place of Presentation: 横浜、メルパルク横浜
• [Presentation] 一側反回神経合併切除症例に対する一期的神経再建術の治療効果 (2013)
  • Author(s): 熊井良彦
  • Organizer: 第25回日本喉頭科学会総会・学術講演会
  • Place of Presentation: 横浜、メルパルク横浜
• [Presentation] 喉頭形成術 (2013)
  • Author(s): 讃岐徹治
  • Organizer: 第25回日本喉頭科学会総会・学術講演会
  • Place of Presentation: 横浜、メルパルク横浜
  • Invited
• [Presentation] Novel strategy for treatmentof severely breathy Dysphonia due tounilateral vocal fold paralysis (2012)
  • Author(s): Yumoto E
  • Organizer: The 8thEast Asian Conference on Phonosurgery
  • Place of Presentation: 済州島、韓国、RamadaPlazaHotell
  • Year and Date: 2012-12-01
• [Presentation] Vocal outcome of the immediatereconstruction of the recurrent laryngealnerve (2012)
  • Author(s): Kumai Y
  • Organizer: The 8th East Asian Conference onPhonosurgery
  • Place of Presentation: 済州島、韓国、Ramada Plaza Hotel
  • Year and Date: 2012-12-01
• [Presentation] Paradoxical movement ofrat vocal fold following recurrentlaryngeal nerve injury (2012)
  • Author(s): Nishimoto K
  • Organizer: The 8th East AsianConference on Phonosurgery
  • Place of Presentation: 済州島、韓国、Ramada Plaza Hotel
  • Year and Date: 2012-12-01
• [Presentation] The modulation of satellitecells in rat thyroarytenoid muscle afterthe transection and immediate anastomosisof recurrent laryngeal nerve (2012)
  • Author(s): Kodama H
  • Organizer: The 8th EastAsian Conference on Phonosurgery
  • Place of Presentation: 済州島、韓国、RamadaPlazaHotel
  • Year and Date: 2012-12-01
• [Presentation] 一側喉頭麻痺に対する喉頭枠組み手術 (2012)
  • Author(s): 讃岐徹治
  • Organizer: 第64回日本気管食道科学会総会・学術講演会(招待講演)
  • Place of Presentation: 東京、ホテル日航東京
  • Year and Date: 2012-11-08
• [Presentation] 一側性喉頭麻痺の診断と治療の流れ (2012)
  • Author(s): 熊井良彦
  • Organizer: 第64回日本気管食道科学会総会・学術講演会(招待講演)
  • Place of Presentation: 東京、ホテル日航東京
  • Year and Date: 2012-11-08
• [Presentation] ラットを用いた反回神経傷害後の共同運動モデルの作製 (2012)
  • Author(s): 西本康兵
  • Organizer: 第64回日本気管食道科学会総会 ・ 学術講演会
  • Place of Presentation: 東京、ホテル日航東京
  • Year and Date: 2012-11-08
• [Presentation] 脱神経後の反回神経切断・縫合処置による甲状披裂筋内の筋衛星細胞の動態 (2012)
  • Author(s): 児玉晴香
  • Organizer: 第64回日本気管食道科学会総会・学術講演会
  • Place of Presentation: 東京、ホテル日航東京
  • Year and Date: 2012-11-08
• [Presentation] 一側喉頭麻痺に対する披裂軟骨内転術と神経筋弁移植術の併用術の効果 (2012)
  • Author(s): 兒玉成博
  • Organizer: 第57回日本音声言語医学会総会・学術講演会
  • Place of Presentation: 大阪、大阪国際交流センター
  • Year and Date: 2012-10-19
• [Presentation] 一側喉頭麻痺における健側声帯過内転と発声機能 (2012)
  • Author(s): 湯本英二
  • Organizer: 第57回日本音声言語医学会総会 ・ 学術講演会
  • Place of Presentation: 大阪、大阪国際交流センター
  • Year and Date: 2012-10-19
• [Presentation] 喉頭筋電図による一側喉頭麻痺に対する神経再建術の術前後評価. (2012)
  • Author(s): 讃岐徹治
  • Organizer: 第57回日本音声言語医学会総会・学術講演会
  • Place of Presentation: 大阪、大阪国際交流センター
  • Year and Date: 2012-10-19
• [Presentation] Reinnervation surgeries fortreatment of severely breathy dysphoniadue to unilateral vocal fold paralysis (2012)
  • Author(s): Yumoto E
  • Organizer: 2012 Meeting of the CollegiumOto-Rhinolaryngologicum Amicitiae Sacrum
  • Place of Presentation: Rome、 イタリア、 Hotel Parco deiPrincipi
  • Year and Date: 2012-08-29
• [Presentation] Ca チャンネル拮抗剤が甲状披裂筋の神経再支配に及ぼす効果 (2012)
  • Author(s): 西本康兵
  • Organizer: 第27回日本耳鼻咽喉科学会九州連合地方部会学術講演会
  • Place of Presentation: 宮崎、シーガイアコンベンションセンター
  • Year and Date: 2012-07-15
• [Presentation] Alignment and Thickness ofthe Vocal Fold After ImmediateReconstruction of the Recurrent LaryngealNerve (2012)
  • Author(s): Yumoto E
  • Organizer: 2012 Meeting of the AmericanBroncho-Esophagological Association(COSM)
  • Place of Presentation: San Diego 、 米 国 、Manchester Grand Hyatt
  • Year and Date: 2012-04-18
• [Presentation] Animal Model for RecurrentLaryngeal Nerve Synkinetic Reinnervationwith Immobile Vocal Fold Using SiliconTube (2012)
  • Author(s): Kumai Y
  • Organizer: 2012 Meeting of the AmericanBroncho-Esophagological Association(COSM)
  • Place of Presentation: San Diego 、 米 国 、Manchester Grand Hyatt
  • Year and Date: 2012-04-18
• [Presentation] The Impact of NimodipineAdministration Combined with Nerve-MusclePedicle Implantation on Long-TermDenervated Rat Thyroarytenoid Muscle (2012)
  • Author(s): Nishimoto K
  • Organizer: 2012 Meeting of the AmericanBroncho-Esophagological Association(COSM)
  • Place of Presentation: San Diego 、 米 国 、Manchester Grand Hyatt
  • Year and Date: 2012-04-18
• [Presentation] 臨床例に即した声帯固定を呈するラット反回神経麻痺モデル (2012)
  • Author(s): 熊井良彦
  • Organizer: 第24回日本喉頭科学会総会 ・ 学術講演会
  • Place of Presentation: 金沢、金沢市文化ホール、金沢ニューグランドホテル
  • Year and Date: 2012-03-08
• [Presentation] 陳旧性一側喉頭麻痺に対する神経再建術後発声機能の経時的評価 (2012)
  • Author(s): 兒玉 成博
  • Organizer: 第24回日本喉頭科学会総会・学術講演会
  • Place of Presentation: 金沢、金沢市文化ホール、金沢ニューグランドホテル
  • Year and Date: 2012-03-08
• [Presentation] Alignment and Thickness of the Vocal Fold After Immediate Reconstruction of the Recurrent Laryngeal Nerve (2012)
  • Author(s): Yumoto E
  • Organizer: 2012 Meeting of the American Broncho-Esophagological Association(COSM)
  • Place of Presentation: San Diego、米国、Manchester Grand Hyatt
• [Presentation] Animal Model for Recurrent Laryngeal Nerve Synkinetic Reinnervation with Immobile Vocal Fold Using Silicon Tube (2012)
  • Author(s): Kumai Y
  • Organizer: 2012 Meeting of the American Broncho-Esophagological Association(COSM)
  • Place of Presentation: San Diego、米国、Manchester Grand Hyatt
• [Presentation] The Impact of Nimodipine Administration Combined with Nerve-Muscle Pedicle Implantation on Long-Term Denervated Rat Thyroarytenoid Muscle (2012)
  • Author(s): Nishimoto K
  • Organizer: 2012 Meeting of the American Broncho-Esophagological Association(COSM)
  • Place of Presentation: San Diego、米国、Manchester Grand Hyatt
• [Presentation] Caチャンネル拮抗剤が甲状披裂筋の神経再支配に及ぼす効果 (2012)
  • Author(s): 西本康兵
  • Organizer: 第27回九州連合地方部会学術講演会
  • Place of Presentation: 宮崎、シーガイアコンベンションセンター
• [Presentation] Reinnervation surgeries for treatment of severely breathy dysphonia due to unilateral vocal fold paralysis (2012)
  • Author(s): Yumoto E
  • Organizer: 2012 Meeting of the Collegium Oto-Rhinolaryngologicum Amicitiae Sacrum
  • Place of Presentation: Rome、イタリア、Hotel Parco dei Principi
• [Presentation] 一側喉頭麻痺における健側声帯過内転と発声機能 (2012)
  • Author(s): 湯本英二
  • Organizer: 第57回日本音声言語医学会総会・学術講演会
  • Place of Presentation: 大阪、大阪国際交流センター
• [Presentation] 喉頭筋電図による一側喉頭麻痺に対する神経再建術の術前後評価 (2012)
  • Author(s): 讃岐徹治
  • Organizer: 第57回日本音声言語医学会総会・学術講演会
  • Place of Presentation: 大阪、大阪国際交流センター
• [Presentation] 一側喉頭麻痺に対する喉頭枠組み手術 (2012)
  • Author(s): 讃岐徹治
  • Organizer: 第64回日本気管食道科学会総会・学術講演会
  • Place of Presentation: 東京、ホテル日航東京
  • Invited
• [Presentation] 一側性喉頭麻痺の診断と治療の流れ (2012)
  • Author(s): 熊井良彦
  • Organizer: 第64回日本気管食道科学会総会・学術講演会
  • Place of Presentation: 東京、ホテル日航東京
  • Invited
• [Presentation] ラットを用いた反回神経傷害後の共同運動モデルの作製 (2012)
  • Author(s): 西本康兵
  • Organizer: 第64回日本気管食道科学会総会・学術講演会
  • Place of Presentation: 東京、ホテル日航東京
• [Presentation] Novel strategy for treatment of severely breathy Dysphonia due to unilateral vocal fold paralysis (2012)
  • Author(s): Yumoto E
  • Organizer: The 8th East Asian Conference on Phonosurgery
  • Place of Presentation: 済州島、韓国、Ramada Plaza Hotel
• [Presentation] Vocal outcome of the immediate reconstruction of the recurrent laryngeal nerve (2012)
  • Author(s): Kumai Y
  • Organizer: The 8th East Asian Conference on Phonosurgery
  • Place of Presentation: 済州島、韓国、Ramada Plaza Hotel
• [Presentation] Paradoxical movement of rat vocal fold following recurrent laryngeal nerve injury (2012)
  • Author(s): Nishimoto K
  • Organizer: The 8th East Asian Conference on Phonosurgery
  • Place of Presentation: 済州島、韓国、Ramada Plaza Hotel
• [Presentation] The modulation of satellite cells in rat thyroarytenoid muscle after the transection and immediate anastomosis of recurrent laryngeal nerve (2012)
  • Author(s): Kodama H
  • Organizer: The 8th East Asian Conference on Phonosurgery
  • Place of Presentation: 済州島、韓国、Ramada Plaza Hotel
• [Presentation] 陳旧性一側喉頭麻庫に対する神経再建術後発声機能の経時的評価 (2012)
  • Author(s): 見玉成博
  • Organizer: 第24回日本喉頭科学会総会・学術講演会
  • Place of Presentation: 金沢市文化ホール、金沢ニューグランドホテル(石川県)
• [Presentation] 臨床例に即した声帯固定を呈するフット反回神経過麻庫モデル (2012)
  • Author(s): 熊井良彦
  • Organizer: 第24回日本喉頭科学会総会・学術講演会
  • Place of Presentation: 金沢市分化ホール、金沢ニューグランドホテル(石川県)
• [Presentation] Nimodipine AcceleratesRe-innervation of Denervated RatThyroarytenoid Muscle FollowingNerve-Muscle Pedicle Implantation (2011)
  • Author(s): Nishimoto K
  • Organizer: 11thTaiwan Japan Otolaryngology Head & NeckConference
  • Place of Presentation: 神戸、ANAクラウンプラザホテル神戸
  • Year and Date: 2011-12-08
• [Presentation] 反回神経傷害後の甲状披裂筋内における神経再生・再支配 (2011)
  • Author(s): 東家 完
  • Organizer: 第63回日本気管食道科学会総会・学術講演会
  • Place of Presentation: 名古屋、名古屋東急ホテル
  • Year and Date: 2011-11-10
• [Presentation] 一側喉頭麻痺に対する神経再建術後発声機能の解析 (2011)
  • Author(s): 兒玉 成博
  • Organizer: 第56回日本音声言語医学会総会 ・ 学術講演会
  • Place of Presentation: 東京、ホテルグランドヒル市ヶ谷
  • Year and Date: 2011-10-06
• [Presentation] 反回神経傷害後の甲状披裂筋内における神経再生・再支配について (2011)
  • Author(s): 東家完
  • Organizer: 第29回頭頸部自律神経研究会
  • Place of Presentation: ホテルグランヴィア大阪(大阪府)
  • Year and Date: 2011-08-27
• [Presentation] 反回神経傷害後の甲状披裂筋内における神経再生・再支配について (2011)
  • Author(s): 東家 完
  • Organizer: 第29回頭頸部自律神経研究会
  • Place of Presentation: 大阪、ホテル グランヴィア大阪
  • Year and Date: 2011-08-17
• [Presentation] 神経障害部位と甲状披裂筋内における神経再生・再支配 (2011)
  • Author(s): 東家 完
  • Organizer: 第26回日本耳鼻咽喉科学会九州連合地方部会学術講演会
  • Place of Presentation: 福岡、萃香園ホテル
  • Year and Date: 2011-07-10
• [Presentation] 神経障害部位と甲状披裂筋内における神経再生・再支配 (2011)
  • Author(s): 東家完
  • Organizer: 第26回九州連合地方部会学術講演会
  • Place of Presentation: 萃香園ホテル(福岡県)
  • Year and Date: 2011-07-10
• [Presentation] Nerve Fibers in LaryngealMuscle Following Injury on Nerve. AmericanAcademy of Otolaryngology-Head and NeckSurgery Foundation (AAO-HNSF) (2011)
  • Author(s): Toya Y
  • Organizer: 2011 AnnualMeeting &OTO EXPO
  • Place of Presentation: サンフランシスコ、米国、Moscone Center
• [Presentation] A New Classification ofLaryngeal Synkinesis. American Academy ofOtolaryngology-Head and Neck SurgeryFoundation (AAO-HNSF) (2011)
  • Author(s): Yumoto E
  • Organizer: 2011 Annual Meeting&OTO EXPO
  • Place of Presentation: サンフランシスコ、米国、Moscone Center
• [Presentation] Nerve-Muscle Pedicle FlapImplantation Combined with ArytenoidAdduction. Nerve-Muscle Pedicle FlapImplantation Combined with ArytenoidAdduction (2011)
  • Author(s): Yumoto E
  • Organizer: 2011 Meeting of the CollegiumOto-Rhinolaryngologicum Amicitiae Sacrum
  • Place of Presentation: ブルージュ、 ベルギー、 Oude SintJan Hospital
• [Presentation] Subjective and ObjectiveVoice Outcomes Following ArytenoidAdduction Plus Nerve-Muscle PedicleTransfer Compared with Simple Vocal FoldMedialization in Paraslytic Dysphonia (2011)
  • Author(s): Mohammed M
  • Organizer: The 7th East Asian Conference onPhonosurgery
  • Place of Presentation: 東京、学術総合センター
• [Presentation] Nerve-Muscle Pedicle Flap Implantation Combined with Arytenoid Adduction (2011)
  • Author(s): Yumoto Eiji
  • Organizer: Collegium Oto-Ehino-Laryngologicum Amicitiae Sacrum
  • Place of Presentation: Oude Sint Jan Hospital(ブルージュ,ベルギー)
• [Presentation] A New Classification of Laryngeal Synkinesis (2011)
  • Author(s): Yumoto Eiji
  • Organizer: American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO
  • Place of Presentation: Moscone Center(サンフランシスコ,米国)
• [Presentation] Nerve Fibers in Laryngeal Muscle Following Injury on Nerve (2011)
  • Author(s): Toya Yutaka
  • Organizer: American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO
  • Place of Presentation: Moscone Center(サンフランシスコ,米国)
• [Presentation] 一側喉頭麻庫に対する神経再建術後発声機能の解析 (2011)
  • Author(s): 見玉成博
  • Organizer: 第56回日本音声言語医学会総会・学術講演会
  • Place of Presentation: ホテルグランドヒル市ヶ谷(東京都)
• [Presentation] 反回神経傷害後の甲状披裂筋内における神経再生・再支配 (2011)
  • Author(s): 東家完
  • Organizer: 第63回日本気管食道科学会総会・学術講演会
  • Place of Presentation: 名古屋東急ホテル(愛知県)
• [Presentation] Nimodipine Accelerates Re-innervation of Denervated Rat Thyroarytenoid Muscle Following Nerve-Muscle Pedicle Implantation (2011)
  • Author(s): Nishimoto Kohei
  • Organizer: 11th Taiwan Japan Otolaryngology Head & Neck Conference
  • Place of Presentation: ANAクラウンプラザホテル神戸(兵庫県)
• [Presentation] Effects of TypeIIThyroplastyin Patients with Adductor SpasmodicDysphonia;Acoustic and AerodynamicFindings (2010)
  • Author(s): Sanuki T.
  • Organizer: The 7th East Asian Conference onPhonosurgery
  • Place of Presentation: 東京、学術総合センター
• [Presentation] Adipose derived stem cell forvocal fold regeneration (2010)
  • Author(s): Kumai Y
  • Organizer: The 4th WorldVoice Congress
  • Place of Presentation: ソウル、韓国、COEX Convention Center
• [Presentation] Myelin Sheath Break down In RatIntrinsic Laryngeal Muscle FollowingRecurrent Laryngeal Nerve Injury (2010)
  • Author(s): Toya Y
  • Organizer: The 4thWorld Voice Congress
  • Place of Presentation: ソウル、韓国、COEX Convention Center
• [Presentation] Management of InsufficientAirway due to Midline Fixation of theBilateral Vocal Folds (2010)
  • Author(s): Yumoto E
  • Organizer: The 4th World VoiceCongress
  • Place of Presentation: ソウル、韓国、COEXConvention Center
• [Presentation] Three-Dimensional Behaviorof the Unilaterally Paralyzed Larynx (2010)
  • Author(s): Yumoto E
  • Organizer: The 4th World Voice Congress
  • Place of Presentation: ソウル、韓国、COEX Convention Center
• [Presentation] Respiratory Function AfterThyroplastic Surgeries (2010)
  • Author(s): Miyamaru S
  • Organizer: The 28th WorldCongress of the International Associationof Logopedics abd Phoniatrics
  • Place of Presentation: アテネ、ギリシア
• [Presentation] Laryngeal Reinnervation-NewHorizons in Treatment of Vocal FoldParalysis (2010)
  • Author(s): Yumoto E
  • Organizer: The 28th World Congress of theInternational Association of Logopedicsabd Phoniatrics
  • Place of Presentation: アテネ、ギリシア
• [Presentation] Effects of Nerve-MusclePedicle on the Rat Immobile Vocal Fold inthe Presence of Recurrent Laryngeal NerveReinnervation (2010)
  • Author(s): Aoyama T
  • Organizer: 2010 Meeting of theAmerican Bronchoesophageal Society
  • Place of Presentation: ラスベガス、米国
• [Presentation] Intubation vs UnspecifiedLaryngeal Granulomas:49 Cases ofRetrospective Analysis (2010)
  • Author(s): Kumai Y
  • Organizer: 2010 Meeting ofthe American Bronchoesophageal Society
  • Place of Presentation: ラスベガス、米国
• [Presentation] Intubation vs Unspecified Laryngeal Granulomas : 49 Cases of Retrospective Analysis (2010)
  • Author(s): Kumai Y
  • Organizer: 2010 Meeting of the American Bronchoesophageal Society
  • Place of Presentation: PALIS LAS VEGASラスベガス(米国)
• [Presentation] Effects of Nerve-Muscle Pedicle on the Rat Immobile Vocal Fold in the Presence of Recurrent Laryngeal Nerve Reinnervation (2010)
  • Author(s): Aoyama T
  • Organizer: 2010 Meeting of the American Bronchoesophageal Society
  • Place of Presentation: PALIS LAS VEGASラスベガス(米国)
• [Presentation] Laryngeal Reinnervation-New Horizons in Treatment of Vocal Fold Paralysis (2010)
  • Author(s): Yumoto E
  • Organizer: 28^<th> World Congress of the International Association of Logopedics abd Phoniatrics
  • Place of Presentation: Athenaeum Intercontinental Hotelアテネ(ギリシア)
• [Presentation] Respiratory Function After Thyroplastic Surgeries (2010)
  • Author(s): Miyamaru S
  • Organizer: 28^<th> World Congress of the International Association of Logopedics abd Phoniatrics
  • Place of Presentation: Athenaeum Intercontinental Hotelアテネ(ギリシア)
• [Presentation] Three-Dimensional Behavior of the Unilaterally Paralyzed Larynx (2010)
  • Author(s): Yumoto E
  • Organizer: 4th World Voice Congress
  • Place of Presentation: COEXソウル(韓国)
• [Presentation] Management of Insufficient Airway due to Midline Fixation of the Bilateral Vocal Folds (2010)
  • Author(s): Yumoto E
  • Organizer: 4th World Voice Congress
  • Place of Presentation: COEXソウル(韓国)
• [Presentation] Myelin Sheath Break down In Rat Intrinsic Laryngeal Muscle Following Recurrent Laryngeal Nerve Injury (2010)
  • Author(s): Toya Y
  • Organizer: 4th World Voice Congress
  • Place of Presentation: COEXソウル(韓国)
• [Presentation] Adipose derived stem cell for vocal fold regeneration (2010)
  • Author(s): Kumai Y
  • Organizer: 4th World Voice Congress
  • Place of Presentation: COEXソウル(韓国)
• [Presentation] Subjective and Objective Voice Outcomes Following Arytenoid Adducation Plus Nerve-Muscle Pedicle Transfer Compared with Simple Vocal Fold (2010)
  • Author(s): Mohammed M
  • Organizer: The 7th East Asian Conference on Phonosurgery
  • Place of Presentation: 学術総合センター東京
• [Presentation] Effects of Type II Thyroplasty in Patients with Adductor Spasmodic Dysphonia ; Acoustic and Aerodynamic Findings (2010)
  • Author(s): Sanuki T
  • Organizer: The 7th East Asian Conference on Phonosurgery
  • Place of Presentation: 学術総合センター東京