| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2014: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2010: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Outline of Final Research Achievements |
On aspect of gene therapy and cellular therapy: 1.Successful engraftment of GFP-positive cells in mouse retina in vivo, 2. Identification of candidate gene in a family of novel congenital anomaly of the optic disc and vitreous by exome analysis, 3. Identification of Pax6 mutations in 23 cases with congenital eye anomalies. On aspect of reproducing medicine: 1. Generation of iPS cells from infantile iris and retina tissue, 2. Generation of the self-induced eye primordium and retina tissue from human iPS cells, 3. Generation of photoreceptor-like cells of the retina from human skin by introduction of external genes, 4. Generation of self-induced retinal ganglion cells with functional axons from human iPS cells.
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