| Budget Amount *help |
¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2012: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2010: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
|
|---|
| Research Abstract |
The objective was to reveal the importance of genetic and environmental factors involved in sleep bruxism. Twins were recruited from the Twin Mothers Club Japan through the Twin Research Center, Osaka University Graduate School of Medicine. Subjects consisted of 84 twins (42 twin pairs, mean age = 22.3± 6.8 yrs.). The total numbers of nocturnal electromyographic activities of the left temporal muscle were recorded with a portable automatic sleep bruxism analyzer. The recordings were carried out for three consecutive nights. The quantitative genetic statistics based on the structural equation modeling was carried out. The result of covariance structure analysis showed that the additive genetic effect was 0.42 and the unique environmental effect was 0.58. According to the result obtained from the present study genetic factors could be considered as a significant contributing factor for the initiation of sleep bruxism. However, the estimated environmental effect at 0.58 suggests the importance of individual evaluation of patients with sleep bruxism.
|
