The toxic substances as a factor of causing the region of a high risk of cancer incidencein China.
Project/Area Number |
22401008
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 海外学術 |
Research Field |
Environmental impact assessment/Environmental policy
|
Research Institution | Prefectural University of Kumamoto |
Principal Investigator |
ARIZONO Koji 熊本県立大学, 環境共生学部, 教授 (70128148)
|
Co-Investigator(Kenkyū-buntansha) |
WATANABE Chiho 東京大学, 医学系研究科 (70220902)
ISHIBASHI Hiroshi 尚絅大学, 短期大学部 (90403857)
YOSHIDA Yoshitoku 名古屋大学, 医学研究科 (90506635)
ISHIBASHI Yasuhiro 熊本県立大学, 環境共生学部 (00212928)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2012: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
|
Keywords | 環境影響評価 / 環境政策 / 汚染 / 中国 / 癌村 / 水質汚染 / バイオアッセイ / リスク評価 / 遺伝毒性 / 一斉スクリーニング / データベース / イムノクロマト / 重金属類 / マイクロアレイ / 遺伝子発現 |
Research Abstract |
The environmental samples (living environment water considered to contain toxic substance) were collected from the region and several the provinces which have a high risk of cancer incidence, and were analyzed the concentration of various chemical substances based on the information on the industrial area in China. As a result, o,p’-DDT was detected. Therefore, the ecology impact evaluation was performed using the DNA microarray of medaka. On the other hand, environmental water and food (agricultural products and a marine product) contamination of metals study using ICP-MS and the immune-chromatography whichspecialized in cadmium were cooperated with China Hainan CDC. At the area which conducted metallic pollution investigation of the heavy metal (cadmium and lead). The local resident's health survey was performed with metal analysis. The lead pollution of the Hainan marine products was detected in 0.005-0.717mg/kg, and River contamination of cadmium was detected 0.100x10-3 - 0.648 mg/kg was detected.
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Report
(4 results)
Research Products
(63 results)
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[Journal Article] Development of a novel GC/MS database for the determination of additives for containers and packaging and its application to processed foods' analysis2013
Author(s)
Nakashima S, Ji H,Ishitobi S, Yamagami T, Asai K, K, Kadokami K, Musuga M, Kawamura Y, Koga M, Shinohara R , Ishibashi H, Tominaga N, Arizono K
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Journal Title
Japanese Journal of Food Chemistry
Volume: 12(1)
Pages: 42-51
Related Report
Peer Reviewed
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[Journal Article] Toxicological effects of glyphosate formulation in Japanese medaka(Oryzas Latipes)2012
Author(s)
Uchida M, Takumi, S, Tachikawa K, Yamauchi R, Goto Y, Matsusaki H,Nakamura H, Kagami Y, Kusano T, Arizono K
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Journal Title
The Journal of Toxicological. Sciences
Volume: Vol. 37 (2)
Pages: 245-254
Related Report
Peer Reviewed
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[Journal Article] Toxicological effects of glyphosate formulation in Japanese medaka (Oryzas Latipes)2012
Author(s)
Uchida M, Takumi, S, Tachikawa K, Yamaushi R, Goto Y, Matsusaki H, Nakamura H, Kagami Y, Kusano T, Arizono K
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Journal Title
The Journal of Toxicological. Sciences, Vol.2012
Volume: 37(2)
Pages: 245-254
Related Report
Peer Reviewed
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