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Molecular epidemiology of livestock parasitic diseases in Myanmar and northern Thailand and isolation of anti-parasitic compounds from medicinal plants

Research Project

Project/Area Number 22405037
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Applied veterinary science
Research InstitutionHokkaido University

Principal Investigator

KATAKURA Ken  北海道大学, (連合)獣医学研究科, 教授 (10130155)

Co-Investigator(Kenkyū-buntansha) SAKURAI Tatsuya  東京慈恵会医科大学, 医学部, 講師 (60547777)
MIYAZAKI Satoshi  北海道大学, (連合)獣医学研究科, 博士研究員 (20547781)
KATO Hirotomo  北海道大学, (連合)獣医学研究科, 准教授 (00346579)
Co-Investigator(Renkei-kenkyūsha) MATSUURA Hideyuki  北海道大学, (連合)農学研究院, 准教授 (20344492)
ITAGAKI Tadashi  岩手大学, 農学部, 教授 (80203074)
SASAKI Hitoshi  酪農学園大学, 短期大学部, 教授 (60105252)
Project Period (FY) 2010-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2012: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2011: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Keywordsミャンマー / 寄生虫 / バベシア / タイレリア / トリパノソーマ / 衛生昆虫 / 疫学 / 薬用植物 / バベシア症 / タイレリア症 / バングラデシュ / トリパノソーマ症
Research Abstract

Epidemiological surveys of livestock parasites, including Babesia, Theileria, Trypanosoma, Toxoplasma, Neospora and Fasciola species, were conducted in Myanmar. The results revealed new insights of distribution, life cycle and evolution of these parasites. On the other hand, isolation and characterization of antitrypanosomal compounds from Myanmar medicinal plants was performed to utilize natural plant products for treatment and prophylaxis of parasitic disease. Results of this study will contribute to establishment of control strategies of parasitic diseases and development of animal husbandry in Myanmar.

Report

(5 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (44 results)

All 2014 2013 2012 2011 2010 Other

All Journal Article (18 results) (of which Peer Reviewed: 16 results) Presentation (17 results) (of which Invited: 5 results) Book (5 results) Remarks (4 results)

  • [Journal Article] Characteristics and molecular phylogeny of Fasciola flukes from Bangladesh, determined based on spermatogenesis and nuclear and mitochondrial DNA analyses2014

    • Author(s)
      Mohanta K, Ichikawa-Seki M, Shoriki T, Katakura K, Itagaki T
    • Journal Title

      Parasitol Res

      Volume: (in press) Issue: 7 Pages: 758-762

    • DOI

      10.1007/s00436-014-3898-5

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Molecular prevalence and genetic diversity of bovine Theileria orientalis in Myanmar2014

    • Author(s)
      Bawm S, Shimizu K, Hirota J, Tosa Y, Htun LL, Maw NN, Thein M, Kato H, Sakurai T, Katakura K
    • Journal Title

      Parasitol Int

      Volume: (in press) Issue: 4 Pages: 640-645

    • DOI

      10.1016/j.parint.2014.04.009

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Genetic diversity of Leishmania donovanl/Infantum complex in China through microsatellite analvsis.2014

    • Author(s)
      Alam, et al.
    • Journal Title

      Infection Genetics and Evolution

      Volume: 22 Pages: 112-119

    • DOI

      10.1016/j.meegid.2014.01.019

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Molecular prevalence and genetic diversity of bovine Theileria orientalis in Myanmar2014

    • Author(s)
      Bawm S, Shimizu K, Hirota J, Tosa Y, Htun LL, Maw NN, Thein M, Kato H, Sakurai T, Katakura K
    • Journal Title

      Parasitol Int

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characteristics and molecular phylogeny of Fasciola flukes from Bangladesh2014

    • Author(s)
      Mohanta K, Ichikawa-Seki M, Shoriki T, Katakura K, Itagaki T
    • Journal Title

      Parasitol Res

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Morphological and Molecular Characterization of <i>Explanatum Explanatum</i> from Cattle and Buffaloes in Myanmar2013

    • Author(s)
      Ichikawa. M., Kondoh, D., Bawn, S., Maw, N. N., Htun, L. L., Thein, M., Gyi, A., Sunn, K., Katakura, K. and Itagaki, T.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 75 Issue: 3 Pages: 309-314

    • DOI

      10.1292/jvms.12-0389

    • NAID

      130001879620

    • ISSN
      0916-7250, 1347-7439
    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] PCR-Based Detection of <i>Leishmania donovani</i> DNA in a Stray Dog from a Visceral Leishmaniasis Endemic Focus in Bangladesh2013

    • Author(s)
      Alam, et al.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 75 Issue: 1 Pages: 75-78

    • DOI

      10.1292/jvms.12-0134

    • NAID

      130001879680

    • ISSN
      0916-7250, 1347-7439
    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] リーシュマニア症の分子疫学:南・東アジアを中心として2013

    • Author(s)
      片倉 賢
    • Journal Title

      獣医寄生虫学会誌

      Volume: 11 Pages: 61-70

    • Related Report
      2013 Annual Research Report
  • [Journal Article] 原虫・寄生虫検査に強くなろう III線虫類、条虫類2013

    • Author(s)
      片倉 賢
    • Journal Title

      臨床と微生物

      Volume: 40 Pages: 347-352

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Isolation of antitrypanosomal compounds from Vitis repens, a medicinal plant of Myanmar2012

    • Author(s)
      Nyunt KS, Elkateeb A, Tosa Y, Nabeta K, Katakura K, Matsuura H
    • Journal Title

      Nat Prod Commun

      Volume: 7 Pages: 609-610

    • URL

      http://www.naturalproduct.us/

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Antitrypanosomal activities of acetylated bruceines A and C ; a structure-activity relationship study2012

    • Author(s)
      Elkhateeb A, et al
    • Journal Title

      Journal of Natural Medicines

      Volume: 66 Issue: 1 Pages: 233-240

    • DOI

      10.1007/s11418-011-0571-5

    • Related Report
      2013 Final Research Report 2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of CD4+ Foxp3+ regulatory T cells in persistence of Leishmania donovani in the liver of alymphoplastic aly/aly mice2012

    • Author(s)
      Tiwananthagorn S, Iwabuchi K, Ato M, Sakurai T, Kato H, Katakura K
    • Journal Title

      PLoS Negl Trop Dis

      Volume: 6 Issue: 8 Pages: 1798-1798

    • DOI

      10.1371/journal.pntd.0001798

    • NAID

      120004756399

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Isolation of antitrypanosomal compounds from Vitis repens, a medicinal plant of Myanmar.2012

    • Author(s)
      Nyunt KS
    • Journal Title

      Natural Product Communications

      Volume: 7 Pages: 609-610

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of Fasciola spp.in Myanmar on the basis of spermatogenesis status and nuclear and mitochondrial DNA markers2011

    • Author(s)
      Ichikawa M, Bawn S, Maw NN, Htun LL, Thein M, Gyi A, Sunn K, Katakura K, Itagaki T
    • Journal Title

      Parasitology International

      Volume: 60 Issue: 4 Pages: 474-479

    • DOI

      10.1016/j.parint.2011.08.007

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Imported leishmaniasis in dogs, US military bases, Japan2010

    • Author(s)
      Kawamura Y, Yoshikawa I, Katakura K
    • Journal Title

      Emerg Infect Dis

      Volume: 16 Issue: 12 Pages: 2017-2019

    • DOI

      10.3201/eid1612.100389

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Myanmar Medicinal Plant Extracts for Antitrypanosomal and Cytotoxic Activities2010

    • Author(s)
      Bawm S, Tiwananthagorn S, Lin KS, Hirota J, Irie T, Htun LL, Maw NN, Myaing TT, Phay N, Miyazaki S, Sakurai T, Oku Y, Matsuura H, Katakura K
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 72 Issue: 4 Pages: 525-528

    • DOI

      10.1292/jvms.09-0508

    • NAID

      130000149957

    • ISSN
      0916-7250, 1347-7439
    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Imported leishmaniasis in dogs, US military bases, Japan2010

    • Author(s)
      Kawamura Y
    • Journal Title

      Emerging and Infectious Diseases

      Volume: 60 Pages: 2017-2019

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Myanmar medicinal plant extracts for antitrypanosomal and cytotoxic activities.2010

    • Author(s)
      Bawn S
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 72 Pages: 525-528

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Studies on antitrypanosomal activity of Myanmar medicinal plants2014

    • Author(s)
      Nyunt K, Elkhateeb A, Katakura K, Matsuura H
    • Organizer
      日本農芸化学学会2014年度大会
    • Place of Presentation
      明治大学生田キャンパス(川崎市)
    • Year and Date
      2014-03-29
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular epidemiological studies on livestock parasites in Myanmar2014

    • Author(s)
      Katakura K
    • Organizer
      First International Conference and the 13^<th> Annual Meeting of Myanmar Veterinary Association
    • Place of Presentation
      Yangon, Myanmar
    • Year and Date
      2014-02-02
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Molecular epidemiological studies on livestock parasites in Myanmar.2014

    • Author(s)
      Katakura K
    • Organizer
      First International Conference and the 13th Annual Meeting of Myanmar Veterinary Association
    • Place of Presentation
      Convention Center, Yangon (ミャンマー)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Studies on antitrypanosomal activity of Myanmar medicinal plants2014

    • Author(s)
      Nyunt K, Elkhateeb A, Katakura K, Matsuura H
    • Organizer
      日本農芸化学学会2014年度大会
    • Place of Presentation
      明治大学生田キャンパス(川崎市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] バングラデシュにおけるイヌのバベシア感染について2013

    • Author(s)
      寺尾将司、Alam M Z、Akter S、中尾 亮、櫻井達也、加藤大智、片倉 賢
    • Organizer
      第156回日本獣医学会学術集会
    • Place of Presentation
      岐阜大学(岐阜市)
    • Year and Date
      2013-09-21
    • Related Report
      2013 Final Research Report
  • [Presentation] ミャンマー産ネズミ亜科4種の分子系統学的把握2013

    • Author(s)
      鈴木 仁、Saw Bawn、片倉 賢
    • Organizer
      第29回日本霊長類学会・日本哺乳類学会2013年度合同大会
    • Place of Presentation
      岡山理科大学(岡山市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] バングラデシュにおけるイヌのバベシア感染について2013

    • Author(s)
      寺尾将司、Alam M Z、Akter S、中尾 亮、櫻井達也、加藤大智、片倉 賢
    • Organizer
      第156回日本獣医学会学術集会
    • Place of Presentation
      岐阜大学(岐阜市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Serological and molecular evidence of Leishmania parasite in dogs of visceral leishmaniasis endemic areas in Bangladesh2013

    • Author(s)
      Alam M Z, Akter S, Yasin Md G, 中尾 亮、櫻井達也、加藤大智、片倉 賢
    • Organizer
      第155回日本獣医学会学術集会
    • Place of Presentation
      東京大学(東京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] バングラデシュの内臓リーシュマニア症流行地における野犬の調査2013

    • Author(s)
      アラム・モハマド・ザハンギル、アクター・シリン、 ヤジン・エムディ・ゴラム、中尾 亮、櫻井達也、加藤大智、片倉 賢
    • Organizer
      第82回日本寄生虫学会大会
    • Place of Presentation
      東京医科歯科大学(東京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ミャンマー連邦におけるウシのピロプラズマ病の疫学調査2012

    • Author(s)
      櫻井達也、土佐祐輔、清水耕平、廣田淳一、近 朋之、加藤大智、片倉 賢
    • Organizer
      第154回日本獣医学会学術集会
    • Place of Presentation
      岩手大学(盛岡市)
    • Year and Date
      2012-09-16
    • Related Report
      2013 Final Research Report
  • [Presentation] ミャンマーとタイ北部における家畜寄生虫症の分子疫学と抗寄生虫薬用植物の探索2012

    • Author(s)
      片倉 賢
    • Organizer
      平成24年度海外学術調査フォーラム
    • Place of Presentation
      東京外国語大学アジア・アフリカ言語文化研究所(府中市)
    • Year and Date
      2012-06-30
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Isolation of antitrypanosomal compounds from Myanmar medicinal plants2012

    • Author(s)
      Nyunt KS, Elkateeb A, Tosa Y, Nabeta K, Katakura K, Matsuura H
    • Organizer
      日本農芸化学学会2012年度大会
    • Place of Presentation
      京都女子大学(京都市)
    • Year and Date
      2012-03-23
    • Related Report
      2013 Final Research Report
  • [Presentation] ミャンマーとタイ北部における家畜寄生虫症の分子疫学と抗寄生虫薬用植物の探索2012

    • Author(s)
      片倉 賢
    • Organizer
      平成24年度海外学術調査フォーラム
    • Place of Presentation
      東京外国語大学アジア・アフリカ言語文化研究所(府中市)
    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Invited
  • [Presentation] ミャンマー連邦におけるウシのピロプラズマ病の疫学調査2012

    • Author(s)
      櫻井達也、土佐祐輔、清水耕平、廣田淳一、近 朋之、加藤大智、片倉 賢
    • Organizer
      第154回日本獣医学会学術集会
    • Place of Presentation
      岩手大学(盛岡市)
    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
  • [Presentation] アジアに分布する肝蛭の系統関係の解明 : タイ産およびミャンマー産肝蛭の分子学的解析2011

    • Author(s)
      市川まどか、Pannigan C、Bawm S、Maw NN、Htun LL、Prusert S、片倉 賢、板垣匡
    • Organizer
      第80回日本寄生虫学会大会
    • Place of Presentation
      東京慈恵会医科大学(東京都)
    • Year and Date
      2011-07-18
    • Related Report
      2013 Final Research Report
  • [Presentation] イントロダクション : 寄生虫病の国内統計、日本獣医寄生虫学会の活動等2011

    • Author(s)
      片倉 賢
    • Organizer
      平成22年度日本獣医師会 獣医学術大会年次大会 獣産公シンポジウム
    • Place of Presentation
      長良川国際会議場(岐阜市)
    • Year and Date
      2011-02-11
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] わが国の寄生虫病の現状と研究展開:寄生虫病の国内統計、獣医寄生虫学会の活動等について2011

    • Author(s)
      片倉賢
    • Organizer
      平成22年度同本獣医師会獣医学術学会年次大会シンポジウム
    • Place of Presentation
      岐阜市、長良川国際会議場 招待講演
    • Year and Date
      2011-02-11
    • Related Report
      2010 Annual Research Report
  • [Book] 獣医公衆衛生学II(アメリカトリパノソーマ症、アフリカトリパノソーマ症、リーシュマニア症、ジアルジア症) (獣医公衆衛生学教育研修協議会編)2014

    • Author(s)
      片倉賢, 他
    • Total Pages
      331
    • Publisher
      文永堂
    • Related Report
      2013 Final Research Report
  • [Book] 獣医公衆衛生学II2014

    • Author(s)
      片倉 賢 (丸山総一、杉山誠編集責任者、獣医公衆衛生学教育研修協議会編)
    • Total Pages
      331
    • Publisher
      文永堂
    • Related Report
      2013 Annual Research Report
  • [Book] 改訂版 人獣共通感染症(リーシュマニア症) (木村哲,喜田宏編)2011

    • Author(s)
      片倉 賢, 他
    • Total Pages
      551
    • Publisher
      医薬ジャーナル社
    • Related Report
      2013 Final Research Report
  • [Book] 改訂版 人獣共通感染症2011

    • Author(s)
      片倉 賢
    • Total Pages
      551
    • Publisher
      リーシュマニア症
    • Related Report
      2011 Annual Research Report
  • [Book] 改訂版 人獣共通感染症2011

    • Author(s)
      片倉賢(共著)
    • Publisher
      医薬ジャーナル社
    • Related Report
      2010 Annual Research Report
  • [Remarks] 研究室ホームページ

    • URL

      http://www.vetmed.hokudai.ac.jp/parasitology01.html

    • Related Report
      2013 Final Research Report
  • [Remarks] 北海道大学大学院獣医学研究科・獣医学部・寄生虫学教室

    • URL

      http://www.vetmed.hokudai.ac.jp/gsexaminationnew/detail/animal/parasitology/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 北海道大学大学院獣医学研究科・獣医学部 寄生虫学教室

    • URL

      http://www.vetmed.hokudai.ac.jp/gsexaminationnew/detail/animal/parasitology/

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.vetmed.hokudai.ac.jp/parasitology01.html

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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