Epidemiological study for identifying risk factors of esophageal adenocarcinoma in north China.
Project/Area Number |
22406021
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 海外学術 |
Research Field |
Public health/Health science
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Research Institution | Niigata University |
Principal Investigator |
AKAZAWA Kohei 新潟大学, 医歯学総合病院, 教授 (10175771)
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Co-Investigator(Kenkyū-buntansha) |
TERAJIMA Kenshi 新潟大学, 医歯学総合病院, 准教授 (00377160)
WAKAI Toshifumi 新潟大学, 医歯学系, 教授 (50372470)
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Project Period (FY) |
2010 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Fiscal Year 2012: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2011: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 疫学 / 国際保健学 / 健康管理 / 保健医療行政 / 地域保健 / 集団検診 / 医療情報学 / 食道扁平上皮癌 / 中国疫学調査 / リスク因子 / 窒素化合物 / ロジスティック回帰分析 / ホットスポット分析 / 食道癌 / 腺癌 / 条件付きロジスティック回帰分析 / マッチングデータ / 環境因子 / 喫煙 / 飲酒 / 扁平上皮癌 |
Research Abstract |
Purpose : A matched case-control study to clarify the risk factors of alcohol and tobacco intake on the development of esophageal adenocarcinoma was collected in Hebei Province of China. Multivariate conditional logistic regression analysis indicated that only alcohol consumption was a significant risk factor for esophageal adenocarcinoma. Additional analysis of the combination of amount and duration of alcohol consumption indicated that heavy drinkers (> 30 ml/day) had significantly higher ORs, irrespective of the duration of alcohol consumption. In conclusion, heavy alcohol consumption increases the risk for esophageal adenocarcinoma independent of the duration of such consumption.
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Report
(4 results)
Research Products
(10 results)
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[Journal Article] Association of Nitrogen Compounds in Drinking Water with Incidence of Esophageal Squamous Cell Carcinoma in Shexian, China2012
Author(s)
Zhang N, Yu C, Wen D, Chen J, Ling Y, Terajima K, Akazawa K, Shan B, Wang S
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Journal Title
The Tohoku Journal of Experimental Medicine
Volume: 226
Issue: 1
Pages: 11-17
DOI
NAID
ISSN
0040-8727, 1349-3329
Related Report
Peer Reviewed
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