| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
In the olfactory system, odor information is represented as a topographic map of neural activities across glomeruli in the olfactory bulb (OB). However, it remains largely unknown how this odor map is transferred to higher brain centers. In the present study, I combined genetic single-neuron labeling and image registration techniques to address this issue in zebrafish. I found that 1) individual OB neurons send axons to multiple forebrain regions, and that 2) each target region receives either non-selective or biased projections from the OB with respect to glomerular classes. These results suggest that different forebrain regions sample distinct combinations of glomerular inputs and create various forms of olfactory representations.
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