| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
In the hippocampus, neurons (granule cells) exceptionally continue to be generated into adulthood. There are adult type neural stem cells that express glial fibrillary acidic protein (GFAP), unlike usual embryonic ones. In this study, we explored the developmental process of neural stem cells producing granule cells from embryonic to early postnatal stages using transgenic mice to visualize GFAP expressing cells. The present results demonstrate that these embryonic neural stem cells express GFAP from the beginning of granule cell production.
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