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Development of motor cortical network for elaborate motor control.

Research Project

Project/Area Number 22500309
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Nerve anatomy/Neuropathology
Research InstitutionKyoto University

Principal Investigator

MIYACHI Shigehiro  京都大学, 霊長類研究所, 准教授 (60392354)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords神経回路網 / サル / 発達 / 運動皮質 / 前頭葉皮質 / 運動制御 / 神経回路
Research Abstract

It has been known that electrical stimulation of the motor-related frontal cortical areas with long pulse trains (~500ms) elicit purposeful movements such as reaching-grasping and bringing hand to mouth in adult macaques. However, if expression of such complex movements by cortical stimulation is innate or developed by postnatal experiences is not clear. We found that such complex behaviors are elicited by cortical stimulation also in the infant macaques. In addition, neuronal input patterns were examined for ‘reaching’ and ‘hand-to-mouth’ areas.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (6 results)

All 2012 2011

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] Multisynaptic projections from the ventrolateral prefrontal cortex to the dorsal premotor cortex in macaques -anatomical substrate for conditional visuomotor behavior2012

    • Author(s)
      Takahara D, Inoue K, Hirata Y, Miyachi S, Nambu A, Takada M and Hoshi E
    • Journal Title

      Eur J Neurosci

      Volume: 36 Pages: 3365-75

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Origins of multisynaptic projections from the basal ganglia to rostrocaudally distinct sectors of the dorsal premotor area in macaques2011

    • Author(s)
      Saga Y, Hirata Y, Takahara D, Inoue K, Miyachi S, Nambu A, Tanji J, Takada M, Hoshi E
    • Journal Title

      Eur J Neurosci

      Volume: 33 Pages: 285-97

    • Related Report
      2012 Final Research Report
  • [Journal Article] Origins of multisynaptic projections from the basal ganglia to rostrocaudally distinct sectors of the dorsal premotor area in macaques2011

    • Author(s)
      Saga, Y., Hirata, Y., Takahara, D., Inoue, K., Miyachi, S., Nambu, A., Tanji, J., Takada, M., and Hoshi, E.
    • Journal Title

      Eur. J. Neurosci

      Volume: 33 Issue: 2 Pages: 285-97

    • DOI

      10.1111/j.1460-9568.2010.07492.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 幼若マカクサル外側前頭前野への皮質-皮質入力2011

    • Author(s)
      宮地 重弘、 平田 快洋、 檜垣 小百合、 黒田 呈子、 宮部 貴子、 高田 昌彦、 大石 高生
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] Differential activities of monkey lateral prefrontal neurons between decisions based on short-term and long-term menories2011

    • Author(s)
      M.NEJIME, M.INOUE, M.SARUWATARI, K.NAKAMURA, S.MIYACHI
    • Organizer
      41st Annual meeting, Society for Neuroscience
    • Place of Presentation
      Washington D.C.(USA)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 幼若マカクサル外側前頭前野への皮質-皮質入力2011

    • Author(s)
      宮地重弘
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜市
    • Related Report
      2011 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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