Morphological classification and synaptic connectivity analysis of retinal neurons by three-dimensional reconstruction
| Project/Area Number |
22500317
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | Hyogo Medical University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2011: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2010: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | ニューロン / 網膜 / 神経回路 / シナプス / マウス / サル / 電子顕微鏡 / 神経科学 / 細胞・組織 |
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| Research Abstract |
(1) We analyzed the allocations of synaptic contacts in microcircuits from rods via rod bipolar to AII amacrine cells, the gap junctions between AII amacrine and ON cone bipolar cells, and the synaptic contacts from OFF bipolar to OFF ganglion cells in the mouse retina.We also made a map of 30 ganglion cells. (2) We made two maps of cones and rods in the fovea (Eccentricity: 0.25～0.45mm) and the peri-fovea (3.06～3.22mm) and discovered thedirect chemical synaptic pathway from rods to OFF cone bipolar cells in the monkey retina.
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Report
(4 results)
Research Products
(9 results)
