| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
Following injection of green fluorescent protein positive (GFP^+) bone marrow (BM) cells into lethally irradiated wild-type mice, the organs of the recipient mice (BM transplantation [BMT] mice) were regenerated . The maintenance of epithelial structure and function is controlled stromal cells. In BMT mice, GFP^+ stromal cells were regenerated fairly rapidly indicating that BM-derived stromal cells play a pivotal role in epithelial renewal and are crucial for maintaining organ structure and function. BM-derived cells in the periphery possess a special “key” to return to the BM and then to migrate to various organs to become resident cells.
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