Basic study on optical coherence tomography to monitor viability in brain
| Project/Area Number |
22500401
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Yamagata University |
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Principal Investigator |
SATO Manabu 山形大学, 大学院・理工学研究科, 教授 (50226007)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIDATE Izumi 東京農工大学, 大学院生物システム応用科学府, 准教授 (70375319)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 生体情報 / 計測 / 脳組織活性 / OCT / 組織温度 / ATP / 脳 / 組織活性 / 拡散光反射 / 分光計測 |
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| Research Abstract |
Relation between brain viability and OCT signal has been investigated. Keeping the tissue temperature after overdose of anesthetizer, the OCT signal has increased before cardiac arrest (CA). For periodical changes of temperature, the negative correlation relation between OCT signal and temperature was shown. There is no influence of anesthetizers for increase of OCT signal. Under the diffuse reflection measurement, the relative increase of 1.2μm light was measured through CA to show the reduction of CcO. In defuse optical measurements from 0.5μm to 0.9μm using slices of brain, the increase of absorption coefficient and the decrease of scattering coefficient were measured. Further researches are necessary for applications.
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Report
(4 results)
Research Products
(36 results)
