| Project/Area Number |
22500433
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
HACHIYA Hiroyuki 東京工業大学, 大学院・理工学研究科, 教授 (90156349)
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| Co-Investigator(Kenkyū-buntansha) |
HIRATA Shinnosuke 東京工業大学, 理工学研究科, 助教 (80550970)
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| Co-Investigator(Renkei-kenkyūsha) |
YAMAGUCHI Tadashi 千葉大学, フロンティアメディカル工学研究開発センター, 准教授 (40334172)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 超音波医科学 / 組織鑑別診断 / びまん性肝疾患 / レイリー分布 / スペックル / 医用超音波 / 定量診断 / 肝炎 / 肝臓疾患 |
|---|
| Research Abstract |
In this study, we developed a new quantitative diagnosis technique to estimate degree of fibrosis of the hepatitis liver using a model that expresses the amplitude distribution of the ultrasonic echo from a fibrotic liver tissue. In the model, the amplitude distribution is composed by three kinds of Rayleigh distribution corresponding to normal, fibrosis, nodule tissues. Using computer simulation, the tissue phantom, the clinical data, it was shown that the new quantitative technique is valid for the quantitative diagnosis of liver hepatitis.
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