Development of sentinel-lymphnode imaging system by ultrasonic tagging fluorescence imaging technique
Project/Area Number |
22500440
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Medical systems
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Research Institution | Tohoku Institute of Technology |
Principal Investigator |
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Project Period (FY) |
2010 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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Keywords | 画像診断システム / 生体光 / 蛍光 / 超音波 / 生体医用光学 / バイオフォトニクス |
Research Abstract |
Fluorescence imaging technique for detecting sentinel-lymphnodeshas been studied. A prototype of a probe-device using ultrasonic modulation of fluorescence, ‘ultrasonic tagging’, was designed and manufactured. Performance to detect a localized fluorophore located at the depth of 20mm in a biological tissue was achieved. To improve the sensitivity for clinical application, which determines fewer amounts of fluorescent molecules, the method to extract the small component of modulated signal has been developed.
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Report
(4 results)
Research Products
(20 results)
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[Journal Article] Circadian regulation of intracellular G-protein signalling mediates inter cellular synchrony and rhythmicity in the suprachiasmatic nucleus2011
Author(s)
M.Doi, A.Ishida, A.Miyake, M.Sato, R.Komatsu, F.Yamazaki, I.Kimura, S.Tsuchiya, H.Kori, K.Seo, Y.Yamaguchi, M.Matsuo, J-M.Fustin, R.Tanaka, Y.Santo, H.Yamada, Y.Takahashi, M.Araki, K.Nakao, S.Aizawa, M.Kobayashi, K.Obrietan, G.Tsujimoto, H.Okamura
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Journal Title
Nature communication
Volume: Vol.2 article#327
Issue: 1
Pages: 327-327
DOI
NAID
Related Report
Peer Reviewed
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