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Mechanistic analysis of mitral regurgitation by mitral valve complex digital imaging using three-dimensional echocardiography

Research Project

Project/Area Number 22500447
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical systems
Research InstitutionKawasaki Medical School

Principal Investigator

HAYASHIDA Akihiro  川崎医科大学, 医学部, 講師 (90435032)

Co-Investigator(Kenkyū-buntansha) YOSHIDA Kiyoshi  川崎医科大学, 医学部, 教授 (60322583)
NEISHI Yoji  川崎医科大学, 医学部, 講師 (80319946)
OKURA Hiroyuki  川崎医科大学, 医学部, 准教授 (30425136)
Co-Investigator(Renkei-kenkyūsha) OGASAWARA Yashuo  川崎医科大学, 医学部, 准教授 (10152365)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords三次元心エコー図法 / 心臓超音波 / 僧帽弁逆流 / 経食道心エコー図法 / 三次元心エコー図
Research Abstract

The aim of the study was to explore the mechanism of functional mitral regurgitation(FMR) in patients with dilated and depressed left ventricle by three-dimensional transesophageal echocardiography. In the group of more than moderate FMR, the positional relationship of the mitral valve complex, mitral annulus, and papillary muscle revealed diversity. The tethering and the tenting length have been considered to be the most important predictor of FMR; however, there was no difference in the magnitude of the tenting and tethering length, we found mitral valve annulus systolic dilatation to be the powerful predictor of FMR.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (30 results)

All 2013 2012 2011 2010 Other

All Journal Article (16 results) (of which Peer Reviewed: 2 results) Presentation (8 results) Book (5 results) Remarks (1 results)

  • [Journal Article] 【循環器疾患患者の外来管理】診断・管理指標2013

    • Author(s)
      林田晃寛
    • Journal Title

      心エコー. 循環器内科

      Volume: 73(3) Pages: 275-80

    • URL

      http://search.jamas.or.jp/link/ui/N318220005

    • Related Report
      2012 Final Research Report
  • [Journal Article] 心不全と僧帽弁閉鎖不全症最近の診断と治 療を含めて2012

    • Author(s)
      林田晃寛, 吉田清
    • Journal Title

      CIRCULATION Up-to-Date

      Volume: 7(5) Pages: 473-79

    • URL

      http://search.jamas.or.jp/link/ui/M925300004

    • Related Report
      2012 Final Research Report
  • [Journal Article] 【慢性心不全の非薬物療法】診るFunctionalMRの診かた2012

    • Author(s)
      林田晃寛.
    • Journal Title

      Heart View

      Volume: 16(5) Pages: 456-60

    • URL

      http://search.jamas.or.jp/link/ui/2012209600

    • Related Report
      2012 Final Research Report
  • [Journal Article] Influence of chronic tethering of the mitral valve on mitral leaflet size and coaptation in functional mitral regurgitation2012

    • Author(s)
      Saito K
    • Journal Title

      JACC Cardiovasc Imaging

      Volume: 5(4) Issue: 4 Pages: 337-45

    • DOI

      10.1016/j.jcmg.2011.10.004

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Normal values of real-time 3-dimensional echocardiographic parameters in a healthy Japanese population: the JAMP-3D Study2012

    • Author(s)
      Fukuda S
    • Journal Title

      Circ J

      Volume: 76(5) Pages: 1177-81

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 心不全と僧帽弁閉鎖不全症 最近の診断と治療を含めて2012

    • Author(s)
      林田晃寛
    • Journal Title

      CIRCULATION Up-to-Date

      Volume: 7 Pages: 473-479

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 【慢性心不全の非薬物療法】 診る Functional MRの診かた.2012

    • Author(s)
      林田晃寛
    • Journal Title

      Heart View

      Volume: 16 Pages: 456-460

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 【内科 疾患インスト ラクションガイド 何をどう説明するか】循環器疾患心臓弁膜症2011

    • Author(s)
      林田晃寛, 吉田清
    • Journal Title

      Medicina

      Volume: 48(11) Pages: 72-74

    • URL

      http://search.jamas.or.jp/link/ui/2012029970

    • Related Report
      2012 Final Research Report
  • [Journal Article] 【心不全診療-予防と治療の最前線】症状と身体所見から心不全を診る2011

    • Author(s)
      林田晃寛,吉田清
    • Journal Title

      日本医師会雑誌

      Volume: 140(4) Pages: 735-38

    • URL

      http://search.jamas.or.jp/link/ui/2011254400

    • Related Report
      2012 Final Research Report
  • [Journal Article] 【心臓血管手術における心血管エコー検査の役割】心臓血管手術僧帽弁形成術僧帽弁逸脱症2011

    • Author(s)
      林田晃寛.
    • Journal Title

      心エコー

      Volume: 12(10) Pages: 894-905

    • URL

      http://search.jamas.or.jp/link/ui/2011335267

    • Related Report
      2012 Final Research Report
  • [Journal Article] 【心臓弁膜症の今日的課題】無症候性重症僧帽弁逆流患者の適正な手術時期2011

    • Author(s)
      林田晃寛.
    • Journal Title

      医学のあゆみ

      Volume: 236(9) Pages: 823-25

    • URL

      http://search.jamas.or.jp/link/ui/L224040001

    • Related Report
      2012 Final Research Report
  • [Journal Article] 心臓血管手術僧帽弁形成術僧帽弁逸脱症2011

    • Author(s)
      林田晃寛
    • Journal Title

      心エコー

      Volume: 12 Pages: 894-905

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 症状と身体所見から心不全を診る2011

    • Author(s)
      林田晃寛
    • Journal Title

      日本医師会雑誌

      Volume: 140 Pages: 735-738

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 循環器疾患心臓弁膜症2011

    • Author(s)
      林田晃寛
    • Journal Title

      Medicina

      Volume: 48 Pages: 72-74

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 無症候性重症僧帽弁逆流患者の適正な手術時期2011

    • Author(s)
      林田晃寛
    • Journal Title

      医学のあゆみ

      Volume: 236巻 Pages: 823-825

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 3D経食道心エコー図による僧帽弁逸脱の定量評価2010

    • Author(s)
      斎藤顕、林田晃寛
    • Journal Title

      Heart View

      Volume: 14巻 Pages: 15-21

    • Related Report
      2010 Annual Research Report
  • [Presentation] 3DEchocardiography2013

    • Author(s)
      林田晃寛
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 弁膜症の身体所見2012

    • Author(s)
      林田晃寛
    • Organizer
      日本心臓病学会第60回学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2012-09-15
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] 大動脈弁狭窄症の重症度評価・弁口面積と圧較差がくい違ったら?2012

    • Author(s)
      林田晃寛
    • Organizer
      日本超音波医学会第85回学術集会
    • Place of Presentation
      東京
    • Year and Date
      2012-05-26
    • Related Report
      2012 Final Research Report
  • [Presentation] 機能性僧帽弁逆流の手術タイミング2012

    • Author(s)
      林田晃寛
    • Organizer
      第23回日本心エコー図学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2012-04-20
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] 三次元心エコー図による僧帽弁疾患の診断2011

    • Author(s)
      林田晃寛
    • Organizer
      日本心臓病学会第59回学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2011-09-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 三次元心エコー図による僧帽弁疾患の診断2011

    • Author(s)
      林田晃寛
    • Organizer
      日本心臓病学会
    • Place of Presentation
      ポートピアホテル(神戸)(招待講演)
    • Year and Date
      2011-09-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 3次元超音波診断の最前線 三次元心エコー図法による弁膜症の定量評価2010

    • Author(s)
      林田晃寛
    • Organizer
      第83回日本超音波医学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Year and Date
      2010-05-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 大動脈弁狭窄の重症度評価 弁口面積と圧較差がくい違ったら?

    • Author(s)
      林田晃寛
    • Organizer
      日本超音波医学会第85回学術集会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Book] 今日の循環器疾患治療指針2013

    • Author(s)
      林田晃寛
    • Total Pages
      4
    • Publisher
      医学書院
    • Related Report
      2012 Annual Research Report
  • [Book] 循環器専門医に必要な検査必須知識2013

    • Author(s)
      林田晃寛
    • Total Pages
      5
    • Publisher
      MEDICAL VIEW
    • Related Report
      2012 Annual Research Report
  • [Book] 実線3D心エコー図法2012

    • Author(s)
      林田晃寛
    • Total Pages
      14
    • Publisher
      南江堂
    • Related Report
      2012 Annual Research Report
  • [Book] 実践3D心エコー図法2011

    • Author(s)
      吉田清
    • Publisher
      南江堂
    • Related Report
      2011 Annual Research Report
  • [Book] 循環器臨床サピア8 心不全の急性期対応2010

    • Author(s)
      林田晃寛、吉田清
    • Total Pages
      6
    • Publisher
      中山書店
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://d.hatena.ne.jp/Cardiology/

    • Related Report
      2012 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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