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Establishments of long term rehabilitation for the unilateral spatial neglect using the transcranial direct current stimulation.

Research Project

Project/Area Number 22500474
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionInternational University of Health and Welfare

Principal Investigator

GOTO YOSHINOBU  国際医療福祉大学, 保健医療学部, 教授 (30336028)

Co-Investigator(Renkei-kenkyūsha) YAMASAKI Takao  九州大学, 大学院医学研究院, 特任助教 (70404069)
KIRIMOTO Hikari  新潟医療福祉大学, 作業療法学科, 准教授 (40406260)
Project Period (FY) 2010-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords半側空間無視(USN) / 経頭蓋直流電流刺激(tDCS) / 事象関連電位 / 放射状運動視刺激(optic flow) / 長期リハビリテーション / 探索眼球運動 / 視覚系と前庭系の相反抑制 / 視覚情報処理 / 半側空間無視 / 経頭蓋直流電流刺激 / 運動視 / リハビリテーション
Research Abstract

It is well known that the higher-level dorsal stream integrates local motion signals from V1 into global motion. Coherent motion, especially radial optic flow (OF) stimulation, will be able to use for evaluating the global motion defects. On the other hand, the new technique, transcranial direct current stimuli (tDCS), will be established for activating the cortical neurons, selectively. In this study, we proposed the new rehabilitation method for USN to use both tDCS and OF visual stimulation. And we analyzed the long term effects of this method. In the results, the psychophysical recognition level of coherent motion and amplitude and latency of two major ERP components (N170 and P200) in USN patients were slightly recovered. Therefore, this combined rehabilitation approach may be useful for the recovering the cognitive functions of USN patients.

Report

(5 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (34 results)

All 2014 2013 2012 2011 2010 Other

All Journal Article (20 results) (of which Peer Reviewed: 16 results) Presentation (11 results) (of which Invited: 2 results) Book (3 results)

  • [Journal Article] 一側前庭神経領域への経頭蓋直流電流刺激が立位姿勢に及ぼす影響. -開閉眼による違い-2014

    • Author(s)
      岡真一郎、後藤純信、他3名
    • Journal Title

      理学療法科学

      Volume: 29

    • NAID

      130004432908

    • Related Report
      2013 Annual Research Report
  • [Journal Article] 運動イメージによる大脳皮質感覚運動関連領域の脳血流変化-巧緻運動と粗大運動の検討-2013

    • Author(s)
      池田拓郎, 佐々木聖馬, 岡真一郎, 後藤純信
    • Journal Title

      理学療法科学

      Volume: 28(2) Pages: 215-219

    • NAID

      10031171554

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 運動イメージによる大脳皮質感覚運動関連領域の脳血流変化-巧緻運動と粗大運動の検討-2013

    • Author(s)
      池田拓郎, 佐々木聖馬, 岡真一郎,後藤純信
    • Journal Title

      理学療法科学

      Volume: 28 Pages: 215-219

    • NAID

      10031171554

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 等輝度色フリッカー刺激を用いた視覚誘発電位の定量解析-正弦波パターンと矩形波パターンによる反応性の相違-2013

    • Author(s)
      後藤和彦、杉剛直、松田吉隆、後藤聡、福田裕樹、後藤純信、他2名
    • Journal Title

      臨床神経生理学

      Volume: 41 Pages: 1-6

    • NAID

      130005003300

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 脳波モデルを用いた視覚誘発電位と後頭部優位律動の振幅推定2012

    • Author(s)
      後藤和彦, 杉剛直, 松田吉隆, 後藤聡, 福田裕樹, 後藤純信, 山崎貴男, 飛松省三
    • Journal Title

      生体医工学

      Volume: 50(6) Pages: 599-606

    • NAID

      130004947545

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 視覚誘発電位記録状態の実時間評価システム2012

    • Author(s)
      後藤和彦, 杉剛直, 松田吉隆, 後藤聡, 福田裕樹, 後藤純信, 山崎貴男, 飛松省三
    • Journal Title

      生体医工学

      Volume: 50(5) Pages: 433-442

    • NAID

      130004494190

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] パーキンソン病患者に対する視覚的刺激による逆説性歩行訓練における効率的歩幅の検討2012

    • Author(s)
      山出宏一, 髙橋精一郎, 後藤純信
    • Journal Title

      理学療法科学

      Volume: 27(5) Pages: 529-533

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Selective impairment of optic flow perception in amnestic mild cognitive impairment : Evidence from event-related potentials2012

    • Author(s)
      Yamasaki T, Goto Y, Ohyagi Y, Monji A, Munetsuna S, Minohara M, Minohara K, Kira J, Kanba S, Tobimatsu S
    • Journal Title

      J Alzheimer's Dis

      Volume: 28(3) Pages: 695-708

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 視覚誘発電位と視覚誘発脳磁場2012

    • Author(s)
      後藤純信, 萩原綱一, 池田拓郎, 飛松省三
    • Journal Title

      臨床神経生理学

      Volume: 40 (1) Pages: 8-18

    • NAID

      10031159657

    • Related Report
      2013 Final Research Report
  • [Journal Article] Selective impairment of optic flow perception in amnestic mild cognitive impairment: Evidence from event-related potentials.2012

    • Author(s)
      Yamasaki T, Goto Y,他8名
    • Journal Title

      J Alzheimer’s Dis

      Volume: 28 Pages: 695-708

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 統合失調症患者の判断難易度に依存しない視覚情報処理機能-探索眼球運動を指標とした検討-2011

    • Author(s)
      早坂友成, 中山広宣, 後藤純信, 森田喜一郎
    • Journal Title

      臨床神経生理学

      Volume: 39(3) Pages: 131-140

    • NAID

      10029428834

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transcranial direct current stimulation over the motor association cortex induces plastic changes in the ipsilateral primary motor and somatosensory cortices2011

    • Author(s)
      Kirimoto H, Ogata K, Onishi H, Oyama M, Goto Y, Tobimatsu S
    • Journal Title

      Clin Neurophysiol

      Volume: 112(4) Pages: 777-783

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural responses in the occipital cortex to unrecognizable faces2011

    • Author(s)
      Mistudo T, Kamio Y, Goto Y, Nakashima T, Tobimatsu S
    • Journal Title

      Clin Neurophysiol

      Volume: 112(4) Pages: 708-718

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 半側空間失認の病態生理2011

    • Author(s)
      後藤純信, 吉田健, 山崎貴男, 中山広宣
    • Journal Title

      認知神経科学

      Volume: 13 (1) Pages: 74-81

    • Related Report
      2013 Final Research Report
  • [Journal Article] Electrophysiological evidence for selective impairment of optic flow perception in autism spectrum disorder2011

    • Author(s)
      Yamasaki T, Fujita T, Ogata K, Goto Y, 他3名
    • Journal Title

      Res Autism Spectrum Disorders

      Volume: 5巻1号 Pages: 400-407

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 暗算負荷による視覚誘発脳磁界の変化2011

    • Author(s)
      水野健太郎, 岡本剛, 池田拓郎, 後藤純信
    • Journal Title

      臨床神経生理学

      Volume: 39巻4号 Pages: 181-191

    • NAID

      10029428976

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 半側空間失認の病態生理2011

    • Author(s)
      後藤純信、吉田健、山崎貴男、中山広宣
    • Journal Title

      認知神経科学

      Volume: 13巻1号 Pages: 74-81

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 探索眼球運動を指標とした脳血管障害者の視覚情報処理機能2010

    • Author(s)
      吉田健, 後藤純信, 中山広宣, 森田喜一郎
    • Journal Title

      臨床神経生理学

      Volume: 38(6) Pages: 371-378

    • NAID

      10029428402

    • Related Report
      2013 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Innovation for Visual Stimuli : From the Retina to Primary Visual Cortex.2010

    • Author(s)
      Goto Y, Yamasaki T, Tobimatsu S
    • Journal Title

      2010 IEEE (CME2010) International Conference on Complex Medical Engineering

      Volume: 1巻1号 Pages: 142-146

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 一側前庭神経領域への経頭蓋直流電流刺激が立位姿勢に及ぼす影響, -開閉眼による違い-

    • Author(s)
      岡真一郎, 後藤純信, 矢倉千昭, 曽田武史, 田原弘幸
    • Journal Title

      理学療法科学

      Volume: (印刷中)

    • NAID

      130004432908

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] Exploratory Eye Movements in Patients with Neurological and Psych iatric Diseases2014

    • Author(s)
      Goto Y
    • Organizer
      14th International Meeting of Physical Therapy Science
    • Place of Presentation
      International Universi ty of Health and Welfare, Ohtawara, Tochigi,Japan
    • Year and Date
      2014-02-08
    • Related Report
      2013 Final Research Report
  • [Presentation] Exploratory Eye Movements in Patients with Neurological and Psychiatric Diseases.2014

    • Author(s)
      Goto Y
    • Organizer
      14th International Meeting of Physical Therapy Science.
    • Place of Presentation
      International University of Health and Welfare, Ohtawara, Tochigi,Japan.
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Innovation for brain science-innovation for visual stimuli : from the retina to high visual pass- way2013

    • Author(s)
      Goto Y
    • Organizer
      12th International Meeting of Physical Therapy Science
    • Place of Presentation
      Eulji University, Seongnam-si, Gyeonggi-do, Korea
    • Year and Date
      2013-07-20
    • Related Report
      2013 Final Research Report
  • [Presentation] Innovation for Brain Science-Innovation for Visual Stimuli: From the Retina to High Visual Passway.2013

    • Author(s)
      Goto Y
    • Organizer
      12th International Meeting of Physical Therapy Science in Korea.
    • Place of Presentation
      Eulji University, Seongnam-si, Gyeonggi-do, Korea.
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 半側空間無視(USN)患者における無視症状と視空間認知機能との関連性について-探索眼球運動(EEMs)と運動視刺激を用いた事象関連電位(ERPs)での検討2012

    • Author(s)
      吉田健, 後藤純信, 他2名
    • Organizer
      第17回認知神経科学会学術集会
    • Place of Presentation
      東京大学先端知ビル武田ホール
    • Year and Date
      2012-09-30
    • Related Report
      2013 Final Research Report
  • [Presentation] 半側空間無視(USN)患者における無視症状と視空間認知機能との関連性について-探索眼球運動(EEMs)と運動視刺激を用いた事象関連電位(ERPs)での検討2012

    • Author(s)
      吉田健、後藤純信、他2名
    • Organizer
      第17回認知神経科学会学術集会
    • Place of Presentation
      東京大学先端知ビル武田ホール
    • Related Report
      2012 Annual Research Report
  • [Presentation] 健常人における左右前庭機能の違い:経頭蓋直流電流刺激を用いた研究2011

    • Author(s)
      岡真一郎, 後藤純信
    • Organizer
      第41回日本臨床神経生理学会学術大会
    • Place of Presentation
      静岡市(グランシップ)
    • Year and Date
      2011-11-12
    • Related Report
      2013 Final Research Report
  • [Presentation] 健常人における左右前庭機能の違い:経頭蓋直流電流刺激を用いた研究2011

    • Author(s)
      岡真一郎, 後藤純信
    • Organizer
      第41回日本臨床神経生理学会学術大会
    • Place of Presentation
      グランシップ(静岡県)
    • Year and Date
      2011-11-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] 半側空間無視の病態生理2010

    • Author(s)
      後藤純信
    • Organizer
      第15回認知神経科学会学術大会
    • Place of Presentation
      松江市(松江テルサ)
    • Year and Date
      2010-07-17
    • Related Report
      2013 Final Research Report
  • [Presentation] 半側空間無視の病態生理2010

    • Author(s)
      後藤純信
    • Organizer
      第15回認知神経科学会
    • Place of Presentation
      松江テルサ(島根県)
    • Year and Date
      2010-07-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Visual evoked magnetic fields to 4 Hz repetitive pattern-reversal stimulation.

    • Author(s)
      Ikeda T, Goto Y, Tobimatsu S
    • Organizer
      18th International Coference on Biomagnetism
    • Place of Presentation
      de la Rochefoucauld d’Estissac, Paris,France
    • Related Report
      2012 Annual Research Report
  • [Book] 視覚誘発電位(VEP):基礎.日本臨床神経生理学会認定委員会編.モノグラフ脳機能計測法を基礎から学ぶ人のために2013

    • Author(s)
      後藤純信, 飛松省三
    • Publisher
      一般社団法人日本臨床神経生理学会発行,一般社団法人学会誌刊行センター製作
    • Related Report
      2013 Final Research Report
  • [Book] Chapter 14: Topography estimation of visual evoked potentials using a combination of mathematical models. In : Wu J (ed.).Biomedical Engineering and Cognitive Neuroscience for Healthcare : Interdisciplinary Applications2013

    • Author(s)
      Sugi T, Goto K, Goto S, Goto Y, Yamasaki T, Tobimatsu S
    • Publisher
      Medical Information Science Reference (IGI Global)
    • Related Report
      2013 Final Research Report
  • [Book] モノグラフ 脳機能計測法を基礎から学ぶ人のために.2013

    • Author(s)
      後藤純信、飛松省三
    • Publisher
      一般社団法人日本臨床神経生理学会発行, 一般社団法人学会誌刊行センター製作
    • Related Report
      2013 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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