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The clinical investigation towards the rehabilitation effect on Parkinson's disease

Research Project

Project/Area Number 22500478
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionJuntendo University

Principal Investigator

HATORI Kozo  順天堂大学, 医学部, 講師 (20286735)

Co-Investigator(Kenkyū-buntansha) NAGAOKA Masanori  順天堂大学, 医学部, 教授 (10138258)
AKAI Masami  国立障害者リハビリテーションセンター, 病院長(研究所併任) (80143452)
SUZUKI Yasushi  国立障害者リハビリテーションセンター, 耳鼻咽喉科, 医長 (30615977)
HATTORI Nobutaka  順天堂大学, 医学部, 教授 (80218510)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsパーキンソン病 / 嚥下障害 / 舌骨 / 嚥下造影検査 / 動作緩慢 / リハビリテ-ション / パ-キンソン病 / 舌骨運動 / リハビリテーション / 嚥下造影 / 舌骨動態 / 無動
Research Abstract

The clinical investigation towards the rehabilitation effect on Parkinson’s disease from the points of view of the swallowing disorders The aim of this study is to evaluate the objective effectiveness of rehabilitation approach in patients with Parkinson’s disease (PD). The diverse effect of rehabilitation on PD was reported in different ways. To evaluate the rehabilitation effects on PDcorrectly encounter considerable difficulty because of the recent clinical progressregarding non ‐ motor symptoms (non ‐ motor parkinsonism), such as depression, fatigability. Non ‐ motor parkinsonism widely affect the effectiveness of the rehabilitation on PD. Non ‐ motor parkinsonism is recognized as primary symptoms antecedent motor symptoms, such as rigidity or bradykinesia. On the basis of this background, we targeted the swallowing disorders in PD because we assumed non‐motor parkinsonism with little regard to swallowing, especially to pharyngeal swallowing. We studied the pharyngeal swallowing focused on hyoid movement in PD with videofluorograph (VF) compared to normal control subjects (NC). PD result in hypokinetic hyoid displacement and hyoid dynamics on pharyngeal swallowing showed narrow amplitude totally compared with NC. Pharyngeal swallowing is the reflex movement subsequent to voluntary triggering of this swallowing process. We consider this process of swallowing will provide us to evaluate the swallowing movement without taking into account the non‐motor parkinsonism. Bradykinesia consists of both narrow amplitude and slowness of movement. Our approachwill provide the useful information about the possibility of the objective finding as to swallowing on PD. The case accumulation was needed to elucidate the swallowing abnormality in PD.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (12 results)

All 2013 2012 2011 2010

All Journal Article (9 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] 特集:パーキンソン病診療の最前線. パーキンソン病の最新のリハビリテーション2012

    • Author(s)
      羽鳥浩三、長岡正範
    • Journal Title

      Modern Physician

      Volume: Vol.32、No.2 Pages: 213-216

    • Related Report
      2012 Final Research Report
  • [Journal Article] Q24パ-キンソン病のリハビリテ-ションの効果は?ここを押さえる!2012

    • Author(s)
      林明人、羽鳥浩三、長岡正範
    • Journal Title

      パ-キンソン病診療、 jmed

      Volume: 23巻 Pages: 118-123

    • Related Report
      2012 Final Research Report
  • [Journal Article] パ-キンソン病診療の最前線. パ-キンソン病の最新のリハビリテ-ション2012

    • Author(s)
      羽鳥浩三
    • Journal Title

      Modern Physician(モダンフィジシャン)

      Volume: 32

    • Related Report
      2012 Annual Research Report
  • [Journal Article] パ-キンソン病のリハビリテ-ションの効果は?ここを押さえる!パ-キンソン病診療2012

    • Author(s)
      林明人
    • Journal Title

      jmed

      Volume: 23

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Effect of vibration stimulation on dysbasia of spastic paraplegia in neuromyelitis optica: a possible example of neuronal plasticity2012

    • Author(s)
      Lin HN
    • Journal Title

      BMJ Case Rep.

      Volume: bcr2012006793. Pages: bcr2012006793-bcr2012006793

    • DOI

      10.1136/bcr-2012-006793

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] パーキンソン病診療の最前線.パーキンソン病の最新のリハビリテーション2012

    • Author(s)
      羽鳥浩三、長岡正範
    • Journal Title

      Modern Physician

      Volume: 32 Pages: 213-216

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 《パーキンソン病を治療する》 パーキンソン病のリハビリテーション2011

    • Author(s)
      羽鳥浩三、長岡正範
    • Journal Title

      内科

      Volume: 107巻 Pages: 849-853

    • Related Report
      2012 Final Research Report
  • [Journal Article] 《パーキンソン病を治療する》パーキンソン病のリハビリテーション2011

    • Author(s)
      羽鳥浩三、長岡正範
    • Journal Title

      内科

      Volume: 107 Pages: 849-853

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Juvenile Muscular Atrophy of a Unilateral Upper Extremity (Hirayama Disease) in a Patient with CHARGE Syndrome2010

    • Author(s)
      Yagihashi, T., Hatori, K., Ishii, K Torii, C., Momoshima, S., Takahashi, T., Kosaki, K.
    • Journal Title

      Molecular Syndromology

      Volume: 1 Pages: 91-94

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] パ-キンソン病(PD)の咽頭期嚥下に関する臨床的検討-舌骨運動解析とPDの運動障害についての考察-2013

    • Author(s)
      羽鳥浩三
    • Organizer
      第36回日本嚥下医学会学術集会
    • Place of Presentation
      みやこめっせ(京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] パーキンソン病の嚥下に関する臨床的検討2011

    • Author(s)
      羽鳥浩三、鈴木康司、石橋郁子、林康子、寺門厚彦、服部信孝、赤居正美、長岡正範
    • Organizer
      第48回日本リハビリテーション医学会学術集会
    • Place of Presentation
      千葉(幕張メッセ)
    • Year and Date
      2011-11-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 痙性対麻痺の歩行障害に振動刺激が有効であったNeuromyelitis opticaの一例2010

    • Author(s)
      林欣霓、林康子、長岡正範、寺門厚彦、羽鳥浩三、高梨雅史、牧雄介
    • Organizer
      第40回日本運動障害研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-24
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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