oles of orexin neuron on the reward based spontaneous voluntary behavior
| Project/Area Number |
22500527
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Physical education
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
INOKAWA Hitoshi 京都府立医科大学, 医学研究科, 講師 (40285250)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 報酬 / 大脳基底核 / ドーパミン / オレキシン / アセチルコリン / 傍細胞記録 / 視床下部 / 黒質 |
|---|
| Research Abstract |
To understand the role of the striatum in value- and strategy-based decision-making and hypothalamic orexin neuron in reward based spontaneous ehavior, we recorded striatal and the orexin neurons in macaque monkeys and rats Large subsets of striatal neurons encoded positive and negative outcome feedbacks of individual decisions and actions. Juxtacellular recording was made in hypothalamic area and investigate orexin neuron by means of immunohistochemical method. This sample is presently being analyzed. These activity profiles as a heterogeneous representation of decision variables may underlie a part of the process for reinforcement- and strategy-based evaluation of selected actions in the striatum.
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Report
(4 results)
Research Products
(4 results)
